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Postdoc Research Symposium

The Biomedical Postdoctoral Council (BPC) and the Office of Biomedical Postdoctoral Programs (BPP) are pleased to announce:

The 7th Annual Postdoctoral Research Symposium
October 24, 2008
BRB II/III Auditorium and Lobby
421 Curie Boulevard, Philadelphia, PA 19104

Abstract Submission Deadline: August 29, 2008
Online Abstract Submission Form

The symposium includes the following events:

This is a great way to practice your presentation skills as well as a FREE educational opportunity for all postdocs organized by the Biomedical Postdoctoral Council (BPC) and Office of Biomedical Postdoctoral Programs (BPP). All accepted abstracts will be published in the Symposium handbook. We look forward to reviewing your abstracts!

Rules and guidelines for abstract submission
Information for Poster Sessions
Information for Oral Sessions
Awards
Keynote Lecture
Contact

I. Rules and Guidelines for abstract submission

Abstract Submission Deadline: August 29, 2008

To submit your abstract please complete the abstract submission form.

Due to space and time limitations, the abstracts will be used to select posters and oral presentations for the symposium. We will also be compiling an abstract book directly from the submissions so please make sure that you adhere to the following guidelines.

 

The following is an example of an abstract that was previously chosen for poster presentation:

                                                 Sample Abstract

Myofibrillogenesis in the First Cardiomyocytes Formed from Isolated Quail Precardiac Mesoderm

Aiping Du (1), Jean M. Sanger (1), Kersti K. Linask (2) and Joseph W. Sanger (1)

(1) Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-6058; (2) Department of Cell Biology, UMDNJ-SOM, Stratford, NJ 08084-1156

The de novo assembly of myofibrils in the first cardiomyocytes was investigated in explants of precardiac mesoderm isolated from quail embryos to address a controversy about different models of myofibrillogenesis. The sequential expression of sarcomeric components was visualized in immunostained explants. In stage 6 explants, cultured for ten hours, ectoderm, endoderm and the precardiac mesoderm display arrays of stress fibers with alternating bands of non-muscle alpha-actinin and nonmuscle-myosinIIB. With increasing time in culture precardiac mesoderm acquired sarcomeric isoforms of alpha-actinin, muscle myosin II and titin. The localization of these proteins supports the model of myofibrillogenesis in which assembly begins with premyofibrils and progresses through nascent myofibrils to mature myofibrils. Fibrils with bands of muscle-specific alpha-actinin alternating with bands of nonmuscle-myosinIIB were present in premyofibrils. In older cultures, fibrils with bands of nonmuscle-myosinIIB and overlapping concentrations of muscle myosin II, nascent myofibrils, were found. The fibrils with non-muscle myosin, premyofibrils and nascent myofibrils, were significantly diminished when the explants became contractile and A-bands of muscle myosin II were detected. In dividing cells, actin, sarcomeric-alpha-actinin, and nonmuscle-myosinIIB were concentrated in the cleavage furrows, while titin and muscle myosin II were not. Inhibition of the assembly of nonmuscle-myosinIIB filaments by ML-7 lead to an inhibition in the assembly of mature myofibrils, that was reversible upon removal of ML-7. These results provide evidence that the premyofibril model of myofibrillogenesis that was originally based on the study of embryonic and adult cardiomyocytes in culture can account for myofibrils formed de novo in the first cardiomyocytes.

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II. Information for Poster Sessions

General Information for all Poster Session Presenters:

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III. Information for Oral Sessions

General Instructions for all Oral Session Presenters

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IV. Awards

Prizes will be awarded to the top presentation in each oral session and the top poster in each poster section. Judges decisions are final and binding. Awards will be presented at the end of the day following the Keynote Lecture.

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V. Keynote Lecture

Our keynote lecturer is Robert Sapolsky, Ph.D., John A. and Cynthia Fry Gunn Professor, Department of Biological Sciences, Stanford University, Departments of Neurology and Neurological Sciences, and of Neurosurgery, Stanford University School of Medicine.

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VI. Contact

If you have any questions regarding abstract submission, general participation or any other issues please contact the Office of Biomedical Postdoctoral Programs at postdoc@mail.med.upenn.edu or 215-573-4332.