Christine Guthrie is Professor of Biochemistry at the University of California at San Francisco and an American Cancer Society Research Professor of Molecular Genetics. Born in Brooklyn, New York and educated at the University of Michigan (BS in Zoology) and the University of Wisconsin (Ph.D. in Genetics), she joined the faculty at UCSF in 1973. The hallmark of her research is the use of genetics to understand molecular mechanisms regulating gene expression.

In recognition of her pioneering use of Saccharomyces cerevisiae to understand the spliceosome, Christine received the 2011 ASBMB-Merck Award. She is a member of the National Academy of Sciences and the American Academy of Arts and Sciences. Christine has long believed that the best science happens in a nurturing environment and received the Women in Cell Biology Senior Career Recognition Award of the American Society for Cell Biology in honor of this practice.