Cancer Genetics and Signal Transduction
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The following GGR laboratories are interested in cancer genetics and signal transduction
Gerd Blobel |
hematopoiesis, gene expression, transcription factors, chromatin |
Douglas Epstein |
Regulation of Sonic hedgehog signaling in development and disease |
Russ Carstens
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Study of the molecular mechanisms of alternative splicing. |
Donna L. George |
Our research interests are focused broadly on the molecular pathways governing cellular growth control and their disruption during the initiation and progression of human cancers. |
Doris Stoffers
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Transcription factors and signal transduction; Embryonic development and adult regeneration of the endocrine pancreas; Relationship of defects in these pathways to the pathophysiology of diabetes mellitus, a disease caused by a deficiency in the production or action of insulin. |
Doris Wagner
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Molecular mechanisms controling developmental transitions in response to environmental and endogenous cues. |
Meera Sundaram
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Regulation and targets of Ras/ERK signaling in C. elegans |
Mitchell Weiss
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Developmental Hematopoiesis concentrating on red blood cell and megakaryocyte lineages. |
Other CAMB laboratories (with research related to GGR) interested in cancer genetics and signal transduction.
| Craig Bassing |
Elucidation of molecular mechanisms which regulate the initiation and proper repair of DNA double strand breaks during chromosomal V(D)J recombination. |
| Eric Brown |
Role of DNA damage responses in preserving genome integrity and preventing cancer. |
| Garrett Brodeur |
Molecular biology and genetics of childhood cancer, especially neuroblastoma. |
| Lewis Chodosh |
Genetically engineered mouse models for breast cancer; Cancer stem cells; Molecular therapeutics; Genomics; Non-invasive imaging. |
| Tom Curran |
The molecular basis of normal and neoplastic growth formation of the brain to uncover new approaches for the treatment of pediatric brain tumors. |
| Brian Keith |
How cells and tissues adapt to oxygen deprivation (hypoxia) by modifying gene expression. |
| Warren Pear |
Processes that control normal development and malignant transformation. |
| Anil Rustgi |
Oncogenes, tumor suppressor genes, molecular genetics of GI cancers (colon, pancreatic, upper GI). |
| Celeste Simon |
Hematopoiesis, angiogenesis, tumorigenesis, and cellular responses to oxygen deprivation. |
| Ben Stanger |
Organogenesis, Stem Cells, Pancreatic Cancer, Regulation of Organ Size. |
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