The following laboratories are interested in signal transduction.
| Yair Argon |
Functions of molecular chaperones in the immune system - modulation of antigen receptors expression and of peptide presentation. |
| Richard Assoian |
Signal transduction and cell cycle control. |
| Kendra Bence | Mouse models of obesity/diabetes, neuronal control of energy balance, protein tyrosine phosphatases, signal transduction. |
| Morris Birnbaum |
The regulation of growth and metabolism. |
| Lawrence F. Brass |
Mechanisms of thrombosis. |
| Janis Burkhardt |
Regulation and function of the T cell cytoskeleton. |
| Margaret Chou |
Mechanisms of malignant transformation; signaling by small GTPases; regulation of vesicular trafficking; ubiquitination. |
| Dennis Discher |
Cell and nuclear membrane structure-function; Adhesion mechanisms and responses of cells; Phagocyte recognition processes; Membrane skeleton and cytoskeleton; Diseases ranging from muscular dystrophy to anemias to athersclerosis; Drug delivery. |
| J. Kevin Foskett |
Ion channels, calcium signaling, cystic fibrosis. |
| Paul Janmey | Cytoskeleton, phosphoinositide signalling, cell mechanics. |
| Gary Koretzky |
Role of adaptor proteins in immune cell develoment and function; Signals leading to T cell activation and termination of T cell responses; In vitro and in vivo function of mast cells and neutrophils; Signals leading to specification of blood vessels and lymphatics. |
| Mark Kahn | Signaling pathways in angiogenesis and hemostasis. |
| Jake Kushner |
Cell cycle, transcriptional regulation of development, adult beta-cell replication. |
| Michael Lampson | Mitotic kinase signaling, chromosome segregation in mitosis and meiosis, kinetochore function. |
| Mark Lemmon |
Signaling by growth factor receptor tyrosine kinases, and inositol phospholipid signaling - biochemical, cellular, and structural biological studies. |
| Judith Meinkoth |
Signal transduction, proliferation, differentiation, apoptosis. |
| Jordan S. Orange |
Directed secretion at the cytolytic immunological synapse; Role of NF-kB activation in cytolytic function |
| Rebecca Wells |
TGF-ß receptor biology; Hepatic stellate cell function in liver fibrosis. |
| Bryan A. Wolf |
Signaling mechanisms of insulin secretion; Cytokines and diabetes. |
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