Yair Argon
|
Functions of molecular chaperones in the immune system - modulation of antigen receptors expression and of peptide presentation. |
Erfei Bi
|
Development of cell polarity and control of cytokinesis in budding yeast. |
Morris Birnbaum
|
The regulation of growth and metabolism. |
Christopher Burd
|
ARF GTPases, Rab GTPases, endocytosis, secretion, phosphatidylinositol kinase signaling. |
Margaret Chou
|
Mechanisms of malignant transformation; signaling by small GTPases; regulation of vesicular trafficking; ubiquitination. |
Andy Dancis
|
Iron transport into mitochondria, Heme sythesis, Fe-S cluster biogenesis, Yeast genetics, and Sideroblastic anemia |
Carol Deutsch
|
Function and assembly of potassium channels in human T lymphocytes. |
Robert Doms
|
HIV; Emerging viral pathogens; Cell biology of Alzheimer's disease. |
J. Kevin Foskett
|
Ion channels, calcium signaling, cystic fibrosis. |
Yale Goldman
|
Relating the structural changes to enzymatic reactions and mechanical steps of the energy transduction mechanism by mapping the real-time domain motions of the motor proteins and ribosomal elongation factors. |
Wei Guo
|
The molecular basis for polarized exocytosis and how exocytosis contributes to polarized cell growth and morphogenesis. |
Erika L. Holzbaur
|
Microtubule-based motility. |
Paul Janmey
|
Cytoskeleton, phosphoinositide signalling, cell mechanics. |
Anna S. Kashina
|
Protein modifications, mouse genetics, cancer, cytoskeleton, cardiovascular development, angiogenesis. |
Mark Lemmon
|
Signaling by growth factor receptor tyrosine kinases, and inositol phospholipid signaling - biochemical, cellular, and structural biological studies. |
Joshua Lipschutz
|
The exocyst complex - as it relates to protein synthesis and trafficking, kidney development (especially cystogenesis and tubulogenesis), and kidney diseases of abnormal synthesis and polarity such as autosomal dominant polycystic kidney disease. |
Frank Luca
|
Yeast and mammalian cell cycle regulation; Cytokinesis.
Daughter cell-specific gene expression; Polarized growth
Mitotic Exit Network (MEN); Regulation of Ace2-dependent transcription and Morphogenesis (RAM). |
Michael S. Marks
|
Regulation and diseases of intracellular protein transport and organelle biogenesis. |
Jordan S. Orange
|
Directed secretion at the cytolytic immunological synapse; Role of NF-kB activation in cytolytic function |
Michael Ostap
|
Molecular mechanisms of cell motility. |
Mechthild Pohlschroder
|
Prokaryotic protein translocation across hydrophobic membranes. |
X. Long Zheng
|
Biosynthesis and Structure-Function of ADAMTS13 Metalloprotease. |
