The following laboratories are interested in muscle, cell motility and cytoskeletal.
Regulation of cell proliferation and differentiation by the extracellular matrix, the actin cytoskeleton, and integrins
|Stephen M. Baylor
||Excitation-contraction coupling; intracellular calcium signaling.|
||Development of cell polarity and control of cytokinesis in budding yeast.|
||Regulation and function of the T cell cytoskeleton.|
||Pathobiology of smooth muscle, signal transduction, myosin, thin filament-associated protein caldesmon, smooth muscle cell differentiation, translational research.|
|Christopher S. Chen
||Regulation of angiogenesis, cancer growth, and stem cell differentiation by adhesive and mechanical cues; Mechanochemical signal transduction; Cadherin and integrin signaling; Rho GTPases and cytoskeletal processes; Cell and tissue engineering.|
Biomechanics in Vascular Biology/Pathology, Hemodynamics and Atherosclerosis, Vascular Cell Communication, Cytoskeletal and membrane biophysics.
|Horace M. DeLisser
||Endothelial Cell Adhesion and Motility.|
||Cell and nuclear membrane structure-function; Adhesion mechanisms and responses of cells; Phagocyte recognition processes; Membrane skeleton and cytoskeleton; Diseases ranging from muscular dystrophy to anemias to athersclerosis; Drug delivery.|
||Relating the structural changes to enzymatic reactions and mechanical steps of the energy transduction mechanism by mapping the real-time domain motions of the motor proteins and ribosomal elongation factors.|
||The molecular basis for polarized exocytosis and how exocytosis contributes to polarized cell growth and morphogenesis.|
|Erika L. Holzbaur
||Cytoskeleton, phosphoinositide signalling, cell mechanics.|
|Anna S. Kashina
||Protein modifications, mouse genetics, cancer, cytoskeleton, cardiovascular development, angiogenesis.|
||Yeast and mammalian cell cycle regulation; Cytokinesis.
Daughter cell-specific gene expression; Polarized growth
Mitotic Exit Network (MEN); Regulation of Ace2-dependent transcription and Morphogenesis (RAM).
||Cell biology, structural biology, cytoskeleton, motility, cell division|
||Molecular mechanisms of cell motility.|
|Benjamin Prosser||Mechano-signaling in heart|
||Roles of the cytoskeleton in cell motility.|
||The cytoskeleton and cellular pattern formation.|
|John W. Weisel
||Intermolecular and cellular interactions in blood clotting, fibrinolysis, and atherosclerosis studied by molecular biophysical methods.|