Genetics of Diabetes and Metabolism
The following GGR laboratories are interested in genetics of diabetes and metabolism
Klaus Kaestner
|
Using modern genetic approaches (expression profiling, gene targeting, tissue-specific and inducible gene ablation) to understand the molecular mechanisms of organogenesis and physiology of the liver, pancreas and gastrointestinal tract. |
Mitchell Lazar
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Regulation of gene expression and metabolism by nuclear hormone receptors. |
Doris Stoffers
|
Transcription factors and signal transduction; Embryonic development and adult regeneration of the endocrine pancreas; Relationship of defects in these pathways to the pathophysiology of diabetes mellitus, a disease caused by a deficiency in the production or action of insulin. |
Other CAMB laboratories (with research related to GGR) interested in genetics of diabetes and metabolism
| Rex Ahima |
Neuroendocrine regulation of body weight and glucose. |
| Morris Birnbaum |
The regulation of growth and metabolism |
| Xianxin Hua |
Elucidating the critical role of the tumor suppressor Menin in regulation of cell proliferation, leukemia and diabetes; investigating signal transduction and epigenetics co-regulated by transforming growth factor beta (TGF-ß) and Menin. |
| Jake Kushner |
molecular regulation of cell cycle, adult beta- cell replication. |
| Catherine Lee May |
Transcriptional regulation of pancreas and gastrointestinal development and function using mouse models |
| Michael Pack |
* Development of the vertebrate digestive system
* Biology and physiology of digestive epithelia and cancers
* High throughput small molecule drug screens |
| Daniel Rader |
Genetic regulation of lipid and lipoprotein metabolism and molecular relationship to atherosclerosis. |
| Bryan Wolf |
Signaling mechanisms of insulin secretion. Cytokines and diabetes. |
back to the GGR program page |
