The following GGR laboratories are interested in bioinformatics and genomics.
The molecular basis of synaptic plasticity, learning and memory; the molecular basis of sleep/wake regulation.
|Roberto Bonasio||Molecular mechanisms of epigenetic memory
|Christopher Brown||We are currently focused on massively parallelizing assays that interrogate non-coding DNA function and applying these approaches to the fine-mapping of the causal variants underlying human disease.|
||Genetic dissection of complex behaviors in mice; Functional genomics|
||Study of the molecular mechanisms of alternative splicing.|
|Alice Chen-Plotkin||I am interested in neurogenerative diseases; my research approach uses genomic-scale screens to identify leads for downstream mechanistic follow-up in cell culture systems.|
|Struan Grant||My current work continues to primarily investigate disease genomics, with a specific focus on pediatrics|
|Hakon Hakonarson||Genetics of common and rare human diseases, using high-throughput sequencing and genotyping approaches.|
||Using modern genetic approaches (expression profiling, gene targeting, tissue-specific and inducible gene ablation) to understand the molecular mechanisms of organogenesis and physiology of the liver, pancreas and gastrointestinal tract.|
|John Murray||Combinatorial control of transcription and cell fate specification, C. elegans development, cellular resolution live imaging|
|Doris Stoffers||Transcription factors and signal transduction; Embryonic development and adult regeneration of the endocrine pancreas; Relationship of defects in these pathways to the pathophysiology of diabetes mellitus, a disease caused by a deficiency in the production or action of insulin.|
|Benjamin Voight||Using statistical genetics, population genetics, and computational biology toward understanding the biological underpinnings and evolutionary history of human phenotypes|
||Molecular mechanisms controling developmental transitions in response to environmental and endogenous cues.|
||Developmental Hematopoiesis concentrating on red blood cell and megakaryocyte lineages.|
|Jeremy Wilusz||Regulation of noncoding RNA biogenesis and function|
|Kenneth Zaret||Mammalian gene regulation, cell differentiation, chromatin structure.|
|Zhaolan (Joe) Zhou||Epigenetic Control of Experience-dependent Gene Expression in Brain Development and Disease|
Other CAMB laboratories (with research related to GGR) interested in bioinformatics and genomics.
|Frederic Bushman||Virology, HIV, Poxviruses, DNA modifying enzymes, Lateral DNA transfer.|
|Sara Cherry||Genetic and mechanistic studies of viral-host interactions.|
|David Roos||Molecular parasitology, host-pathogen interactions, drug targets & resistance mechanisms, evolution of eukaryotic cells & organellar function, genome databases & database mining, comparative genomics, computational biology, Toxoplasma gondii, Plasmodium falciparum.|
|Jun Zhu||Quorum Sensing, Bacterial pathogenesis, Biofilms, Vibrio cholerae.|
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