Cell & Molecular Biology Graduate Group

CAMB Home » GGR Program » Epigenetics and Chromatin

Epigenetics and Chromatin

The following GGR laboratories are interested in epigenetics and chromatin

(Edwin) Ted Abel
The molecular basis of synaptic plasticity, learning and memory; the molecular basis of sleep/wake regulation.
Michael Atchison
Control of Gene Expression, development, and oncogenesis.
Shelley Berger
Chromatin structure and function in gene regulation; post-translational modifications of transcription factors and histones; genetic, biochemical and structural analysis of chromatin in S. cerevisiae and human cells; role of interrelated factor/histone modifications in cancer and viral infection.
Gerd Blobel

Hematopoiesis, gene expression, transcription factors, chromatin

Roberto Bonasio Molecular mechanisms of epigenetic memory
Noncoding RNAs
Chromatin biochemistry
Christopher Brown We are currently focused on massively parallelizing assays that interrogate non-coding DNA function and applying these approaches to the fine-mapping of the causal variants underlying human disease.
Maya Capelson *Nuclear structure and its role in gene regulation
*Spatial organization of the genome
*Epigenetic memory of gene expression states
Jennifer Cremins  
Hua-Ying Fan Chromatin structure regulation by ATP-dependent chromatin remodelers and its impact on disease; Mechanisms of transcription memory.
Susan Janicki
Live cell analysis of epigenetic regulatory mechanisms.
Klaus Kaestner
Using modern genetic approaches (expression profiling, gene targeting, tissue-specific and inducible gene ablation) to understand the molecular mechanisms of organogenesis and physiology of the liver, pancreas and gastrointestinal tract.
Brett Kaufman
The role of mitochondrial chromatin organization in gene expression, resistance to damage, and genome transmission.
Mitchell Lazar
Regulation of gene expression and metabolism by nuclear hormone receptors.
Stephen Liebhaber
Roles of chromatin structure and epigenetic controls in eucaryotic gene activation; Roles of mRNA-protein interactions in control of eucarytic mRNA stability and expression.
John Murray Combinatorial control of transcription and cell fate specification, C. elegans development, cellular resolution live imaging
John R. Pehrson
Role of histone variants in regulating chromatin structure and function
Eileen M. Shore
Genetic diseases of bone formation and development; Molecular and cell biology of bone formation and osteoblast differentiation; Transcriptional activation and regulation of bone morphogenetic protein and GNAS1 target genes.
Doris Stoffers
Transcription factors and signal transduction; Embryonic development and adult regeneration of the endocrine pancreas; Relationship of defects in these pathways to the pathophysiology of diabetes mellitus, a disease caused by a deficiency in the production or action of insulin.
Doris Wagner
Molecular mechanisms controling developmental transitions in response to environmental and endogenous cues.
Kenneth Zaret
Mammalian gene regulation, cell differentiation, chromatin structure.
Zhaolan Zhou Epigenetic Control of Genome Function in Brain Development and Disease

Other CAMB laboratories (with research related to GGR) interested in epigenetics and chromatin

Marisa Bartolomei Genomic imprinting and X inactivation in mice.
Jonathan Epstein Transcriptional regulation of cardiac development and function using mouse models.
Peter Klein Early vertebrate development, Wnt signal transduction, neuropharmacology of lithium action
John McLaughlin genomic imprinting, somatic cell reprogramming, embryonic stem cells
Steve Reiner Transcriptional control of lymphocyte differentiation.
Gene silencing, chromatin structure and DNA methylation.
Richard Schultz Egg activation and gene expression in mouse embryos.

back to the GGR program page