Cell & Molecular Biology Graduate Group

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Post-Transcriptional Gene Regulation

The following GGR laboratories are interested in post-transcriptional gene regulation

Michael Atchison
Control of Gene Expression, development, and oncogenesis.
Russ Carstens Study of the molecular mechanisms of alternative splicing.
Gideon Dreyfuss
RNA-binding proteins, nuclear transport of proteins and mRNAs, RNA processing, neurodegenerative disease, high throughput approaches to drug discovery.
Brian Gregory RNA silencing, RNA degradation, RNA stability, microRNAs, small RNAs
Thomas Jongens
Modeling Fragile X Mental Retardation in Drosophila; Germ Cell Specification
Brett Kaufman
The role of mitochondrial chromatin organization in gene expression, resistance to damage, and genome transmission.
Mitchell Lazar
Regulation of gene expression and metabolism by nuclear hormone receptors.
Stephen Liebhaber
Roles of chromatin structure and epigenetic controls in eucaryotic gene activation; Roles of mRNA-protein interactions in control of eucarytic mRNA stability and expression.
Frank Lee
Molecular mechanisms of the hypoxic response
Kristin Lynch Mechanisms and consequences of alternative pre-mRNA splicing, in particular how splicing patterns change in T cells during an immune response to alter cellular function.
Zissimos Mourelatos
MicroRNAs, RNA interference.
John Murray Combinatorial control of transcription and cell fate specification, C. elegans development, cellular resolution live imaging
Doris Stoffers
Transcription factors and signal transduction; Embryonic development and adult regeneration of the endocrine pancreas; Relationship of defects in these pathways to the pathophysiology of diabetes mellitus, a disease caused by a deficiency in the production or action of insulin.
Kazuko Nishikura
RNA metabolism/processing. RNA editing, RNAi mechanism, apoptosis, cell cycle regulation.
J. Eric Russell Control and function of human embryonic globin genes.
Zhaolan (Joe) Zhou Epigenetic Control of Experience-dependent Gene Expression in Brain Development and Disease

Other CAMB laboratories (with research related to GGR) interested in post-transcriptional gene regulation

Constantinos Koumenis
Tumor hypoxia, Unfolded Protein Response, translational regulation of gene expression.

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