The following laboratories are interested in
muscle, cell motility and cytoskeletal
| Charles
Abrams
|
Phospholipid
signaling in platelet and T-cells. |
Stephen
M. Baylor
|
Excitation-contraction coupling;
intracellular calcium signaling. |
Erfei
Bi
|
Development of cell polarity
and control of cytokinesis in budding yeast. |
Janis
Burkhardt
|
Regulation and function of
the T cell cytoskeleton. |
Samuel
Chacko
|
Pathobiology of smooth muscle,
signal transduction, myosin, thin filament-associated
protein caldesmon, smooth muscle cell differentiation,
translational research. |
Christopher
S. Chen
|
Regulation of angiogenesis,
cancer growth, and stem cell differentiation by adhesive
and mechanical cues; Mechanochemical signal transduction;
Cadherin and integrin signaling; Rho GTPases and cytoskeletal
processes; Cell and tissue engineering. |
Janis
Burkhardt
|
Regulation and function of
the T cell cytoskeleton. |
Peter
Davies
|
Biomechanics in Vascular
Biology/Pathology, Hemodynamics and Atherosclerosis,
Vascular Cell Communication, Cytoskeletal and membrane
biophysics. |
Horace
M. DeLisser
|
Endothelial Cell Adhesion
and Motility. |
Dennis
Discher
|
Cell and nuclear membrane
structure-function; Adhesion mechanisms and responses
of cells; Phagocyte recognition processes; Membrane skeleton
and cytoskeleton; Diseases ranging from muscular dystrophy
to anemias to athersclerosis; Drug delivery. |
| Clara Franzini-Armstrong |
|
Yale
Goldman
|
Relating the structural changes
to enzymatic reactions and mechanical steps of the energy
transduction mechanism by mapping the real-time domain
motions of the motor proteins and ribosomal elongation
factors. |
Wei
Guo
|
The molecular basis for polarized
exocytosis and how exocytosis contributes to polarized
cell growth and morphogenesis. |
Erika
L. Holzbaur
|
Microtubule-based motility. |
Paul
Janmey
|
Cytoskeleton, phosphoinositide
signalling, cell mechanics. |
Anna
S. Kashina
|
Protein modifications, mouse
genetics, cancer, cytoskeleton, cardiovascular development,
angiogenesis. |
Frank
Luca
|
Yeast and mammalian cell cycle
regulation; Cytokinesis.
Daughter cell-specific gene expression; Polarized growth
Mitotic Exit Network (MEN); Regulation of Ace2-dependent
transcription and Morphogenesis (RAM). |
John
Murray
|
Cell biology, structural biology,
cytoskeleton, motility, cell division |
Jordan
S. Orange
|
Directed secretion at the
cytolytic immunological synapse; Role of NF-kB activation
in cytolytic function |
Michael
Ostap
|
Molecular mechanisms of cell
motility. |
Tatyana
Svitkina
|
Roles of the cytoskeleton
in cell motility. |
Phong
Tran
|
The cytoskeleton and cellular
pattern formation. |
John
W. Weisel
|
Intermolecular and cellular
interactions in blood clotting, fibrinolysis, and atherosclerosis
studied by molecular biophysical methods. |
Tim
J. Yen
|
Understanding the structure
and function of kinetochores as a means to elucidate mechanisms
of chromosome alignment and mitotic checkpoint control. |
