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Cell and Molecular Biology Graduate Group


 

Developmental Genetics

 

The following GGR laboratories are interested in developmental genetics

Michael Atchison
Control of Gene Expression, development, and oncogenesis.
Gerd Blobel

hematopoiesis, gene expression, transcription factors, chromatin

Douglas Epstein
Regulation of Sonic hedgehog signaling in development and disease
Joshua R. Friedman
Liver development, biliary disease
Thomas Jongens
Modeling Fragile X Mental Retardation in Drosophila; Germ Cell Specification
Thomas Kadesch
notch signaling and the transcriptional regulation of cell differentiation and transformation
Eric Moss Developmental timing, microRNA function, post-transcriptional regulation of gene expression, developmental genetics of C. elegans.
Kazuko Nishikura
RNA metabolism/processing. RNA editing, RNAi mechanism, apoptosis, cell cycle regulation.
Mortimer Poncz Role of platelets in thrombus development
Nancy Spinner
Human Genetics, Notch signaling in human disease, Alagille syndrome, human disease gene identifcation by mapping deletions.
Eileen M. Shore
Genetic diseases of bone formation and development; Molecular and cell biology of bone formation and osteoblast differentiation; Transcriptional activation and regulation of bone morphogenetic protein and GNAS1 target genes.
Doris Stoffers
Transcription factors and signal transduction; Embryonic development and adult regeneration of the endocrine pancreas; Relationship of defects in these pathways to the pathophysiology of diabetes mellitus, a disease caused by a deficiency in the production or action of insulin.
Meera Sundaram
Regulation and targets of Ras/ERK signaling in C. elegans
Doris Wagner
Molecular mechanisms controling developmental transitions in response to environmental and endogenous cues.
Mitchell Weiss
Developmental Hematopoiesis concentrating on red blood cell and megakaryocyte lineages.
Kenneth Zaret
Mammalian gene regulation, cell differentiation, chromatin structure.
Jumin Zhou Mechanism of epigenetic inheritance, long-range transcription activation, insulator and anti-insulators.

Other CAMB laboratories (with research related to GGR) interested in developmental genetics.

Greg Bashaw Signaling mechanisms that function during attractive and repulsive axon guidance.
E. Bryan Crenshaw Analysis of the role of developmental regulatory factors during mouse embryogenesis.
Steve DiNardo Stem Cell Function; developmental patterning.
Jonathan Epstein Transcriptional regulation of cardiac development and function using mouse models.
Amin Ghabrial How cells make and shape tubular organs
Michael Granato Axonal guidance and motor behavior regulation in the zebrafish.
Greg Guild Shaping Drosophila cells with the actin cytoskeleton.
Volker Haase The role of oxygen, the VHL tumor suppressor and HIF in cell growth and apoptosis, angiogenesis and extracelluar matrix formation/fibrosis; Kidney cancer and ischemic cell injury; Podocyte biology, von Hippel-Lindau disease (VHL); Conditional gene targeting technology and transgenesis; Embryonic stem (ES) cells; Mouse model systems.
Olena Jacenko Molecular mechanisms of skeletal development and blood cell differentiation.
Brian Keith How cells and tissues adapt to oxygen deprivation (hypoxia) by modifying gene expression.
Catherine Lee May Transcriptional regulation of pancreas and gastrointestinal development and function using mouse models.
Sarah Millar Intercellular signals regulating the development of hair follicles, teeth and mammary glands and postnatal hair growth.
Ed Morrisey Lung development, cardiac development, vascular development, Wnt signaling, regulation of gene transcription, GATA factors, forkhead factors.
Mary Mullins BMP signal transduction; molecular mechanisms of cell specification establishment of the vertebrate body plan via maternal control mechanisms.
Michael Pack Genetic analysis of vertebrate digestive organ development using the zebrafish.
Micahel Parmacek Transcriptional programs that regulate cardiovascular development.
Scott Poethig Regulation of developmental timing and organ polarity in plants.
Richard Schultz Egg activation and gene expression in mouse embryos.
Celeste Simon Hematopoiesis, angiogenesis, tumorigenesis, and cellular responses to oxygen deprivation.
Ben Stanger Organogenesis, Stem Cells, Pancreatic Cancer, Regulation of Organ Size.
Eric Weinberg Pattern formation, neural development, ear development in the zebrafish embryo.

 

 

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