|
The following GGR laboratories work with C.
elegans
| Eric
Moss |
Developmental timing, microRNA
function, post-transcriptional regulation of gene expression,
developmental genetics of C. elegans. |
| David
Raizen |
The regulation and purpose
of sleep-like behavior in C. elegans. |
| Meera
Sundaram |
Regulation
and targets of Ras/ERK signaling in C. elegans |
Other CAMB laboratories (with research related
to GGR) that work with C. elegans.
|
Todd Lamitina |
Molecular mechanisms
of environmental stress sensing and signaling. |
The following GGR laboratories work with drosophila
| Michael
Atchison
|
Control of Gene Expression, development, and oncogenesis.
|
Thomas
Jongens
|
Modeling Fragile X Mental
Retardation in Drosophila; Germ Cell Specification |
Amita
Sehgal
|
Molecular basis of behavior |
| Jumin
Zhou |
Mechanism of epigenetic inheritance,
long-range transcription activation, insulator and anti-insulators. |
Other CAMB laboratories (with research related
to GGR) that work with drosophila
Greg
Bashaw |
Signaling mechanisms
that function during attractive and repulsive axon guidance.
|
Morris
Birnbaum
|
The regulation of growth and
metabolism. |
| Sara
Cherry |
Genetic and mechanistic studies
of viral-host interactions. |
| Steve
Dinardo |
Stem cell function; developmental
patterning. |
| Amin Ghabrial |
How cells make and shape tubular
organs |
| Greg
Guild |
Shaping Drosophila cells with
the actin cytoskeleton. |
The following GGR laboratories work with mice
(Edwin)
Ted Abel
|
The molecular
basis of synaptic plasticity, learning and memory; the
molecular basis of sleep/wake regulation. |
Michael
Atchison
|
Control of Gene Expression,
development, and oncogenesis. |
| Edward
S. Brodkin |
Genetic analysis of social
behaviors (aggressive and affiliative behaviors) and related
brain phenotypes in mouse models relevant to autism and
schizophrenia. |
Douglas
Epstein
|
Regulation of Sonic hedgehog
signaling in development and disease |
Nancy
Cooke
|
The role of chromatin structure
in eukaryotic gene regulation. |
David
L. Gasser
|
Genes that affect the immune
response |
Joshua
R. Friedman
|
Liver development, biliary
disease |
Jonathan
P. Katz
|
Functional analysis of gastrointestinal
development, proliferation, and differentiation. |
Frank
Lee
|
Molecular mechanisms of the
hypoxic response. |
Nina
Luning Prak
|
mobile DNA, rearrangement
of immunoglobulin genes, regulation of L1 retrotransposition |
Kazuko
Nishikura
|
RNA metabolism/processing.
RNA editing, RNAi mechanism, apoptosis, cell cycle regulation. |
John
R. Pehrson
|
Role of histone variants in
regulating chromatin structure and function |
Eric
Pierce
|
Molecular bases of inherited
retinal degenerations. |
| Mortimer
Poncz |
Role of platelets in thrombus
development |
J.
Eric Russell
|
Control and function of human
embryonic globin genes. |
Doris
Stoffers
|
Transcription factors and
signal transduction; Embryonic development and adult regeneration
of the endocrine pancreas; Relationship of defects in
these pathways to the pathophysiology of diabetes mellitus,
a disease caused by a deficiency in the production or
action of insulin. |
Mitchell
Weiss
|
Developmental Hematopoiesis
concentrating on red blood cell and megakaryocyte lineages. |
Kenneth
Zaret
|
Mammalian gene regulation,
cell differentiation, chromatin structure. |
Other CAMB laboratories (with research related
to GGR) that work with mice
| Marisa
Bartolomei |
Genomic imprinting
and X inactivation in mice. |
| Eric
Brown |
Role of DNA damage responses
in preserving genome integrity and preventing cancer. |
| Lewis
Chodosh |
Genetically engineered mouse
models for breast cancer; Cancer stem cells; Molecular
therapeutics; Genomics; Non-invasive imaging. |
| E.
Bryan Crenshaw |
Analysis of the role of developmental
regulatory factors during mouse embryogenesis. |
| Tom
Curran |
The molecular basis of normal
and neoplastic growth formation of the brain to uncover
new approaches for the treatment of pediatric brain tumors. |
| Jonathan
Epstein |
Transcriptional regulation
of cardiac development and function using mouse models. |
| Xianxin
Hua |
The critical role of the tumor
suppressor Menin in regulation of cell proliferation,
apoptosis, and genome stability.
Signal transduction mediated by transforming growth factor
beta (TGF-b). |
| Olena
Jacenko |
Molecular mechanisms of skeletal
development and blood cell differentiation. |
| Brad
Johnson |
Molecular biology of aging,
Werner syndrome, telomeres, recombination. |
| Anna
Kashina |
Protein modifications, mouse
genetics, cancer, cytoskeleton, cardiovascular development,
angiogenesis. |
| Catherine
Lee May |
Transcriptional regulation
of pancreas and gastrointestinal development and function
using mouse models. |
| Sarah
Millar |
Intercellular signals regulating
the development of hair follicles, teeth and mammary glands
and postnatal hair growth. |
| Ed
Morrisey |
Lung development, cardiac
development, vascular development, Wnt signaling, regulation
of gene transcription, GATA factors, forkhead factors. |
| Michael
Parmacek |
Transcriptional programs that
regulate cardiovascular development. |
| Daniel
Rader |
Genetic regulation of lipid
and lipoprotein metabolism and molecular relationship
to atherosclerosis. |
| Susan
Ross |
Genetic approaches to the
study of host-virus interactions. |
| Anil
Rustgi |
Oncogenes, tumor suppressor
genes, molecular genetics of GI cancers (colon, pancreatic,
upper GI). |
| Richard
Schultz |
Egg activation and gene expression
in mouse embryos. |
| Celeste
Simon |
Hematopoiesis, angiogenesis,
tumorigenesis, and cellular responses to oxygen deprivation. |
| Ben
Stanger |
Organogenesis, Stem Cells,
Pancreatic Cancer, Regulation of Organ Size. |
The following GGR laboratories work with plants
Doris Wagner
|
Molecular
mechanisms controling developmental transitions in response
to environmental and endogenous cues. |
Other CAMB laboratories (with research related
to GGR) that work with plants
| Scott
Poethig |
Regulation of
developmental timing and organ polarity in plants. |
The following GGR laboratories work with S.
cerevisiae
Shelley
Berger
|
Chromatin
structure and function in gene regulation; post-translational
modifications of transcription factors and histones;
genetic, biochemical and structural analysis of chromatin
in S. cerevisiae and human cells; role of interrelated
factor/histone modifications in cancer and viral infection. |
| Aaron
D. Gitler |
Genetic and cellular mechanisms
of neurodegeneration |
Hillary
Nelson
|
Regulation of the heat shock
transcription factor |
Other CAMB laboratories (with research related
to GGR) that work with S. cerevisiae
| Erfei
Bi |
Development of
cell polarity and control of cytokinesis in budding yeast. |
| Chris
Burd |
ARF GTPases, Rab GTPases,
endocytosis, secretion, phosphatidylinositol kinase signaling. |
| Andrew
Dancis |
Iron transport into mitochondria,
Heme sythesis, Fe-S cluster biogenesis, Yeast genetics,
and Sideroblastic anemia |
| Wei
Guo |
The molecular basis for polarized
exocytosis and how exocytosis contributes to polarized
cell growth and morphogenesis. |
| Brad
Johnson |
Molecular biology of aging,
Werner syndrome, telomeres, recombination. |
| Frank
Luca |
Yeast and mammalian cell cycle
regulation; Cytokinesis.
Daughter cell-specific gene expression; Polarized growth
Mitotic Exit Network (MEN); Regulation of Ace2-dependent
transcription and Morphogenesis (RAM). |
The following GGR laboratories work with zebrafish
Other CAMB laboratories (with research related
to GGR) that work with zebrafish
| Jonathan
Epstein |
Transcriptional regulation
of cardiac development and function using mouse models |
| Michael
Granato |
Axonal guidance
and motor behavior regulation in the zebrafish. |
| Dan
Kessler |
* Establishment and organization
of the primary germ layers
* Formation and function of the Spemann organizer in axial
development
* Signaling and transcriptional networks in the vertebrate
gastrula |
| Ed
Morrisey |
lung development, cardiac
development, vascular development, Wnt signaling, regulation
of gene transcription, GATA factors, forkhead factors |
| Mary
Mullins |
BMP signal transduction; molecular
mechanisms of cell specification establishment of the
vertebrate body plan via maternal control mechanisms. |
| Michael
Pack |
Genetic analysis of vertebrate
digestive organ development using the zebrafish. |
| Jonathan Raper |
developmental neurobiology,
especially axon guidance |
| Eric
Weinberg |
Pattern formation, neural
development, ear development in the zebrafish embryo. |
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