Center for Brain Injury and Repair
University of Pennsylvania

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John Q. Trojanowski, M.D., Ph.D.

John Q. Trojanowski, MD, PhD

Professor of Pathology and Laboratory Medicine

William Maul Measey-Truman G. Schnabel Jr., M.D. Professor of Geriatric Medicine and Gerontology

Director, Institute on Aging

Director, Alzheimer’s Disease Core Center

Director, NINDS Morris K. Udall Parkinson's Disease Research Center of

Co-director, Center for Neurodegenerative Disease Research and Marian S. Ware Alzheimer Drug Discovery Program

Dr. Trojanowski obtained his M.D./Ph.D. in 1976 from Tufts University in Boston. After a medicine internship at Mt. Auburn Hospital and Harvard Medical School, he began pathology/neuropathology training at Massachusetts General Hospital and Harvard Medical School (1977-1979), and completed his training at the University of Pennsylvania School of Medicine in 1980 where he was appointed assistant professor of Pathology and Laboratory Medicine (1/1/1981), and rose to the rank of tenured full professor (6/1/1990). Dr. Trojanowski held or currently holds major leadership positions at the University of Pennsylvania including: Director of a National Institute of Aging (NIA) Alzheimer’s Disease Core Center (1991-present), Principal Investigator of a NIA Program Project Grant on Alzheimer’s (AD) and Parkinson’s (PD) disease (1990-2010), Director of Medical Pathology (1988-2002), Interim Director (2001-2002) and Director (2002-present) of the Institute on Aging, founding Co-Director (1992-present) of the Center for Neurodegenerative Disease Research, Director, National Institute of Neurological Disorders and Stroke (NINDS) Morris K. Udall Parkinson’s Disease (PD) Research Center of Excellence (2007-present), the first William Maul Measey-Truman G. Schnabel, Jr., M.D., Professor of Geriatric Medicine and Gerontology (2003-present) and Co-director of the Marian S. Ware Alzheimer Drug Discovery Program (2004-present). For >20 years, Dr. Trojanowski has conducted research on AD, PD, amyotrophic lateral sclerosis, dementia with Lewy bodies (DLB), frontotemporal lobar degeneration (FTLD) and other aging related nervous system disorders. Most of his >700 publications focus on the pathobiology of neurodegenerative disorders, especially the role of abnormal protein aggregates (misfolded proteins) in these diseases. The major goal of his research now is to translate understanding on mechanisms of aging related neurodegenerative diseases into meaningful diagnostics and interventions to treat or prevent these disorders. Dr. Trojanowski has received awards for his research including: a MERIT Award (1986-1994) from the National Institutes of Health (NIH), the Metropolitan Life Foundation Promising Investigator Award For Alzheimer’s Disease Research (1991), membership in the American Society of Clinical Investigation (1991), an Established Investigator Award from the National Alliance for Research on Schizophrenia and Depression (1994), the Metropolitan Life Foundation Award For Alzheimer’s Disease Research (1996), the Potamkin Prize For Research In Pick’s, Alzheimer’s And Related Diseases (1998), the first Pioneer Award from the Alzheimer’s Association (1998-2003), ISI Highly Cited Researcher (among the top 5 most highly cited neuroscientists from 1997 to 2007), the Stanley Cohen Biomedical Research Award of the University of Pennsylvania (2000), membership in the Association of American Physicians (2000), the 2004 Irving Wright Award of Distinction of the American Federation for Aging Research, the 2005 Rous-Whipple Award of the American Society for Investigative Pathology and the 24th Annual Robert J. and Claire Pasarow Foundation Award in Neuropsychiatry Research. He was elected President of the American Association of Neuropathologists (1997-1998). Dr. Trojanowski was elected to the Institute of Medicine (2002) and he has served or continues to serve on local and national aging research committees including: NIA Neuroscience, Behavior and Sociology of Aging Study Section (1987-1991), National Advisory Council on Aging (NACA) of the NIA (1994-1998), NACA Working Group Chair (1996-1998), Medical and Scientific Advisory Board of the National Alzheimer’s Association (1994-1997) as well as of the Southeastern Pennsylvania Chapter of the Alzheimer’s Association (1992-present), NIA Board of Scientific Counselors (1998-2002), Scientific Advisory Boards of the Paul Beeson Physician Faculty Scholars In Aging Award (1998-2002), the Alliance for Aging Research (2002-present) and the Association of Frontotemporal Dementia (2003-present), and the Organizing Committee of the International Conferences On Progress In Alzheimer’s And Parkinson’s Disease (2001-2010). To help the public understand what is needed to cure and/or prevent disorders like AD, Dr. Trojanowski led an effort to prepare an educational film on healthy brain aging and AD (“Alzheimer’s Disease-Facing the Facts”) that airs on >80% of PBS outlets throughout 2009. This film has won a 2008 CINE “Golden Eagle Award” and a 2009 Emmy Award for short documentary films.

Hospital of the University of Pennsylvania's Department of Pathology and Laboratory Medicine
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