Nonhuman Primate Core Services
- Nonhuman Primate Pilot Grant Program
- Regulatory oversight and assistance in acquiring nonhuman primates
- Consultation on study design for nonhuman primate studies
- Routine veterinary care and husbandry
- Perform aspects of HIV-related research studies using nonhuman primates
- Clinical Laboratory Services
- Anatomic Pathology
A complete gross and histological examination is performed on each animal that dies of spontaneous or experimental causes. Blood, bile, intestinal contents, and cerebrospinal fluid are collected for routine analysis and bacterial and/or viral culture, and then archived. A complete set of tissues are preserved in 10% neutral buffered formalin for routine histology. Additional tissues are collected for cryopreservation in OCT (for immunohistochemistry) or wrapped in foil (DNA/RNA isolation or culture) according to a standard necropsy checklist.
The Histology Laboratory has extensive experience with preparing tissue for histological examination and staining these tissues with a variety of histochemical, immunohistochemical, and immunofluorescence stains as well as in situ hybridization for SIV/SHIV. This includes double label immunohistochemistry and immunohistochemistry combined with in situ hybridization.
- Confocal microscopy and image analysis
- Flow cytometry and immunology
- Viral characterization, isolation and production
Core Services Contact:
Andrew A. Lackner, D.V.M., Ph.D.