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Penn Center for AIDS Research

Viral / Molecular Core Virology Services

Core Services Main Page | Virology | Molecular | Sequencing | SGA Services | Intergrated vDNA | Other

Ordering Information:
Order Virology Support services through the Path BioResource at Penn. Instructions for the Path BioResource can be found here on the CFAR website or on the Path BioResource site itself.

Core Service Contact:
Farida Shaheen, Ph.D.
Technical Director, Viral and Molecular Core
Tel: 215-898-5180
Fax: 215-573-4446
Email: farida@mail.med.upenn.edu

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HIV-1 viral isolate repository

The Viral/Molecular Core maintains a Virus Repository with high quality stocks of HIV-1 prototype and primary isolates of various phenotypes, including drug resistant viruses and accessory gene mutants. Viruses are grown in permissive cells, titered by p24 antigen content, verified by V3 sequence fingerprinting and confirmed mycoplasma-free by PCR. They are available in 0.5 ml aliquots. We frequently add new viruses to the repository, so if there is an isolate you would like to use and do not find here, please

 

As an added convenience for Penn CFAR members, we have stocks of frequently-used UNAIDS/NIH AIDS Repository isolates, and a blanket MTA in place so individual investigators do not need to complete paperwork and MTA individually.

The viruses available include:

Prototype HIV-1 Strains   Primary HIV-1 Isolates
X4/T-tropic
R5/M-tropic
R5X4/Dual-tropic
  T-tropic or X4/SI
M-tropic or R5
Neonatal Isolates
Dual-Tropic Primary Isolates
Drug-Resistant Isolates
Transmitted Founder Isolates
Chronic Control Isolates
     
HIV-1 mutant viruses   SIV/SHIV Strains

Ordering Information:
Order Virology Support services through the Path BioResource at Penn. Instructions for the Path BioResource can be found here on the CFAR website or on the Path BioResource site itself.

Fees:
HIV-1 primary M-tropic $16.50 per vial
HIV-1 primary T or dual-tropic $16.50 per vial
HIV-1 prototype M-tropic $16.50 per vial
HIV-1 prototype T- or dual-tropic $15.50 per vial
HIV-1 mutants $16.50 per vial
SIV/SHIV $20.00 per vial