CNDR In Press and Publications
CNDR is focused on improving the understanding, diagnosis and treatment of late-life neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease, Amyotrophic Lateral Sclerosis, Pick’s disease, Lewy body dementia, and related diseases and has established an internationally recognized research program focused on these disorders.
Here is a sampling of some of CNDR's recent mentions in the press regarding research and findings.
Here is a selection of recent publications based on research conducted at CNDR.
Recent Research Mentions
| 2008 | 2007 | 2006 | 2005 |
From 2008:
- News Release from Penn Medicine, June 16, 2008
Lou Gehrig’s Disease Protein Found Throughout Brain, Suggesting Effects Beyond Motor Neurons, Find Penn Researchers - News Release from Penn Medicine, May 16, 2008
Dismantling Alzheimer’s Disease: Penn Researchers Discover How Small Molecule Can Take Apart Disease-Associated Protein Fibers - News Release from Penn Medicine, April 7, 2008:
More Genes for Lou Gehrig’s Disease Identified, According to Penn Researchers
From 2007:
- From the Philadelphia Inquirer, September 4, 2007
Costly error in health research by Tom Avril - Lee, Trojanowski, and coworkers identify a mutant protein in patients diagnosed with Lou Gerhig's disease that has little to do with the vast majority of human cases prompting scientists to rethink their research. - From Newsday.com, May 9, 2007
Piece of ALS puzzle eyed - Scientists say protein may be key to fatal motor neuron disease by Jamie Talan - News release from Penn Medicine, May 4, 2007
New data suggests current approach to drug discovery for Lou Gehrig's disease be re-examined - Penn researchers find two forms of the disease biochemically different. - New release from Penn Medicine, April 11, 2007
Stop and go: Proteins important in Alzheimer’s, Parkinson’s Disease travel in the slow lane - University of Pennsylvania Health System's news release of the paper "Rapid and Intermittent Cotransport of Slow Component-b Proteins" written by Dr. Subhojit Roy, Matthew Winton, Mark Black, John Trojanowski, and Virginia Lee published in the Journal of Neuroscience, March 21, 2007 - From the Palm Beach Daily News, March 5, 2007
"Experts: What helps heart also aids brain" by David Rogers
Drs. John Trojanowski and Virginia Lee are quoted in the article highlighting a link between high cholesterol and dementia.
From 2006:
- From The Philadelphia Inquirer, October 6, 2006
"Key link discovered in dementia, ALS" by Tom Avril
Reaction to article in October 6, 2006 Science "Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis" detailing the breakthrough by Penn researchers in indentifying the abnormal accumulation of same protein in both amyotrophic lateral sclerosis (Lou Gehrig's disease) and frontotemporal dementia. Science (2006) 314:130-133
Download the article - "Neurodegenerative Diseases: New Concepts of Pathogenesis and Their Therapeutic Implications" by Daniel M. Skovronsky, Virginia M.-Y. Lee, and John Q. Trojanowski. From Annual Review of Pathology: Mechanisms of Disease (2006) 1:151-170. download a pdf file
From 2005:
- "7 Ways to Save a Brain": download an article from Newsweek magazine (June 27, 2005) on new therapies to slow the progress of Alzheimer's Disease
- Vitamin E and Alzheimer's Disease: download an article from January 5, 2005; download response.