News in Neurodegenerative Disease Research
Read on for more on the latest research news from the CNDR lab, news from the Center for Neurodegenerative Disease Research (CNDR), general news in neurodegenerative disease research, and for information on upcoming events of interest.
CNDR in the News
- Drs. John Trojanowski and Virginia Lee to Speak at PennNYC Event: Untangling Alzheimer’s: A Key to Healthy Aging on May 22nd. More information...
- CNDR Study Shows Potential Alzheimer's Disease Drug Slows Damage and Symptoms in Animal Model. More information and interview...
- IOA Fellows Drs. Trojanowski, Lee, and Schellenberg Presenting at Brain Degenerations and Emerging Mental Health Challenges in Sub-Saharan Africa, February 1-3. More information...
- Drs. Virginia Lee & John Trojanowski on the Protein Road Map to Alzheimer's. Sciencewatch Interview...
- CNDR Research Questions Role of A-Beta Molecules in Alzheimer's Pathology. More information...
- CNDR Forms Informatics Partnership with Johnson & Johnson to Improve Alzheimer's Disease Monitoring. More information...
- Penn-Led Alzheimer's Disease Consortium Identifies New Genes for Alzheimer's Risk. More information...
- Research at CNDR Shows Malfunctioning Gene Associated with ALS Leads to Nerve-Cell Death in Mice. More information...
- Untangling Alzheimer's - The Pennsylvania Gazette Looks at the Research in Alzheimer's Disease and Other Neurodegenerative Diseases from Virginia Lee, John Trojanowski, and Others at Penn. More information...
- Penn Medicine Blog: The On-Going Saga of a Disease Protein. How Discoveries Unfold and the Story of TDP-43. More information...
- Drs. Lee and Trojanowski interviewed on Fox 29 about their Alzheimer's research efforts.
- Alzheimer's Disease Neuroimaging Initiative, with Biomarker Core at Penn, Enters Next Phase of Research. NIA press release...
- Blood test for Alzheimer's, developed largely at Penn, cited as #3 on TIME’s Top 10 Medical Breakthroughs of 2010. More information...
- Penn’s research in Alzheimer’s diagnostics was ranked #10 in Discover Magazine’s list of the top stories of 2010. More information...
- Initial Analysis of ADNI Plasma Proteome Data Suggests Possible Protein Signatures for Alzheimer's. More information...
- Penn Researchers Develop First Blood Test to Determine Cognitive Impairment in Parkinson's Disease. More information...
- Alzheimer's test developed largely at Penn, under the leadership of Drs. Shaw and Trojanowski, proves effective. Penn Medicine press release...
- ADVANCE interview with Dr. Les Shaw: AD Biomarker in Lab Medicine and Aging. More information...
- Drs. Lee and Trojanowski featured in New York Times' article, "Taking an Alternative Path in Fighting the Disease." Click here to read the article...
- Alzheimer Research Forum presents "Of mice and men: bridging the translational disconnect in CNS drug discovery," featuring Hugo Geerts, from In Silico Biosciences and Consultant to the Marian S. Ware Alzheimer Program at CNDR, as well as Kurt Brunden, PhD, Scientific Director, Marian S. Ware AD and Benaroya PD Drug Discovery Programs and Steven Arnold, MD, Associate Director of the IOA and Director of the Penn Memory Center. More information...
- CNDR and AstraZeneca Working Together to Find New Therapies for Alzheimer’s Disease. More information...
- Penn Researchers Find New Risk Factor for Second-Most-Common Form of Early-Onset Dementia - Examining brain tissue from over 500 individuals in 11 countries, researchers found a new risk factor for the second-most-common cause of early-onset dementia after Alzheimer’s disease.
- Alex Crowe, Research Specialist; Kurt R. Brunden, PhD, Director of Drug Discovery at Penn’s Center for Neurodegenerative Disease Research (CNDR); Virginia M.-Y. Lee, PhD, and John Q. Trojanowski,CNDR Co-Directors, and their colleagues at the National Institutes of Health (NIH) Chemical Genomics Center (NCGC) have discovered a new class of compounds for potentional Alzheimer's disease drug. For more information, click here.
- "Alzheimer’s Disease: Facing the Facts," a documentary initiated at CNDR, wins a 2009 Emmy for Documentary Program. More information...
- Philadelphia philanthropists John O. Haas and Dr. Janet Haas support pilot studies in Alzheimer’s disease drug discovery. More information...
Virginia M.-Y. Lee, PhD, MBA, Director of CNDR, received a 2009 Lifetime Achievement Award from the Alzheimer's Association at its International Conference on Alzheimer's Disease. Dr. Lee was recognized for her work determining the genesis and roles of various normal and abnormal brain proteins. For more information on this year's ICAD, click on the logo above. - John Q. Trojanowski, MD, PhD, Director of the Institute on Aging, Steve Arnold, MD, Director of the Alzheimer's Disease Center, and Melissa Livney, Psyc.D., clinical psychologist at the Alzheimer's Disease Center, were featured on WHYY’s Radio Times with Marty Moss-Coane discussing Alzheimer’s disease. More information...
- National coverage of "New Test Can Detect Early Alzheimer's" (Reuters). For the official Penn press release, click here.
- More Genes For Lou Gehrig's Disease Identified - Mutations have been found in a disease protein called TDP-43 that is implicated in two neurodegenerative disorders: amyotrophic lateral sclerosis (ALS), also called Lou Gehrig's disease, and certain types of frontotemporal dementia (FTD)
Dr. John Trojanowski was interviewed in February 2008 for SAGE Crossroads about the biomarkers of aging and the key to advancing longevity science. Click here to connect with the interview - marked #36.- Rapid Response: Read the response from Dr. Steven Arnold, Associate Director of the Penn Alzheimer's Disease Center and Penn Memory Center, to a newly published case report in the Journal of Neuroinflammation describing a novel treatment for Alzheimer’s disease, Perispinal Etanercept. (January 2008)
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CNDR's Dr. Virginia Lee poses with the newly inagurated mayor of Philadelphia, Michael Nutter, on January 17, 2008 after ceremonies to lay a wreath on the grave of Benjamin Franklin, part of the Celebration of Benjamin Franklin, Founder ceremonies and in honor of Franklin's birthday.
- On January 17, a 2008 Benjamin Franklin Founder award was given to Dr. Virginia Lee for exemplifying the the talent of taking “what you find that is curious” and translating it into something that more than certainly “may be useful.” Read more about it.
News in Neurodegenerative Disease Research and Advocacy:
- Penn Researchers Find Brain Insulin Resistance Contributes to Cognitive Decline in Alzheimer's Disease. More information...
- Penn Biologist Nancy Bonini and Colleagues Identify a Key Enzyme Involved in Protecting Nerves from Degeneration, with Implications for Neurodegenerative Diseases. More information...
- Penn Receives $16 Million Gift to Launch New Initiative Focusing on the Neuroscience of Behavior. More information...
- Penn Researchers and Colleagues Find That Size Matters: Measuring Brain Thickness Identifies Those at High Risk for Cognitive Decline, Penn Study Shows. More information...
- Penn Alzheimer's Disease Center receives renewed funding for five years. More information...
- Dr. Gerard Schellenberg Leads Penn Portion of First International Collaboration on the Genetics of Alzheimer's Disease. More information...
- A Single, Traumatic Brain Injury May Prompt Long-Term Neurodegeneration. More information...
- Penn-Led Alzheimer's Disease Consortium Identifies New Genes for Alzheimer's Risk. More information...
- Proposed guidelines for diagnosing Alzheimer's updated. PDF of Criteria for AD Dementia.
- Midlife Heart Risk Factors Linked to Later Dementia
- Discovery Sheds Light on Huntington's Disease
- 2010 update on the Alzheimer's disease epidemic is out from the Alzheimer’s Association
- 2010 world report on Alzheimer's disease from the Alzheimer's Association. Report
- Alzheimer's Study Group: A Source Document on Thinking About Alzheimer's Disease.
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"Can Alzheimer's Disease Be Prevented?," a newly updated booklet from the National Institute on Aging (NIA), answers questions about brain health and summarizes the latest research about AD prevention. More information... - Click here for more on The Alzheimer's Project, a multi-platform public health series that seeks to bring a wider public understanding of Alzheimer's disease research and care. Co-presented by HBO and NIA.
- Alzheimer's Association released its 2009 Alzheimer's Facts and Figures Report and the Alzheimer's Study Group has released its National Alzheimer's Strategic Plan today as part of a hearing on the group’s work before the Senate Special Committee on Aging.