Alzheimer's Disease Prevention
Principal Investigator: Yvette Sheline, M.D (NIH funded)
Alzheimer’s disease is a devastating illness with no currently proven effective preventive therapies. This two-year, federally funded study seeks to investigate the effect of taking a certain types of antidepressant medication, Selective Serotonin Reuptake Inhibitors (SSRIs), on the production of a certain type of protein in the brain that is associated with Alzheimer’s disease, known as an Amyloid Beta protein (Aβ).
Who we are looking for:
- English speaking, right-handed adults, ages 60-85 with no history of neurological injury or disease
- People with no history of neurological injury or disease
- People with no current or recent past history of antidepressant use
What you will do:
- Office visits over 3 months, including cognitive testing, 2 spinal taps, 1 blood draw
- Take an antidepressant or placebo for 2-8 weeks and be assessed for biological changes
- Receive compensation!
If you are interested in participating or would like more information, you can take this brief survey or contact the CNDS: