Electron Microscopy Resource Laboratory
Core Description: The Electron Microscopy Resource Laboratory (EMRL ) at Penn is a research facility dedicated to ultrastructure analysis of biological samples by electron microscopy (EM). We offer high quality EM imaging services at low cost. With a team of experienced professional staff and state-of-the-art sample preparation and imaging equipment, the EMRL offers users a full spectrum of both transmission EM and scanning EM services. These services include: specimen preparation (including high pressure freezing, chemical fixation, microwave tissue processing, and sectioning of cells and tissues or preparation of non-cellular materials), operation of equipment, data acquisition, data interpretation, and training on all aspects of EM analysis. EMRL also offers assistance in tomographic and single particle image reconstruction techniques. We also offer assistance on the preparation of manuscript and grant applications that incorporate various forms of EM analysis.