Maureen Maguire

Maureen G. Maguire, PhD received her doctoral degree in 1983 from the Department of Biostatistics, Johns Hopkins School of Hygiene and Public Health and joined the faculty of the Department of Ophthalmology, School of Medicine, Johns Hopkins University.   She became thoroughly versed in the responsibilities and procedures of coordinating centers through her work with two established clinical trial groups.  The Macular Photocoagulation Study (MPS), a series of 8 NEI-supported randomized clinical trials, was conducted 1979-1992.  The Coordinating Center was housed in the Wilmer Clinical Trials and Biometry Unit, School of Medicine.  Dr. Maguire served in increasingly more responsible positions (protocol monitor, biostatistician, senior biostatistician, deputy director) within the Coordinating Center.  Between 1983 and 1989, Dr. Maguire was Biostatistician and Deputy Director for the Glaucoma Laser Trial, housed in the Center for Clinical Trials, School of Public Health.  Experience with two different approaches to data management and study administration provided a strong basis for future work.  In 1985 she became Principal Investigator and Director of the Coordinating Center for the Collaborative Corneal Transplantation Trials.   During this period, she also collaborated on multiple clinical research projects with colleagues in the Department of Ophthalmology and in teaching research methods with colleagues in the Welch Center for Prevention, a joint venture of the Schools of Medicine and Public Health.

In July 1994, Dr. Maguire joined the faculty of the University of Pennsylvania to establish the Center for Preventive Ophthalmology and Biostatistics (CPOB).  Since then, she has held leadership positions in several multicenter clinical trials for the prevention and treatment of age-related macular degeneration sponsored by industry and the NIH.  In addition, she was actively involved in the development of the Vision In Preschoolers Study, an NEI-sponsored, multicenter, clinical investigation of methods for screening young children for vision problems. 

Dr. Maguire is now the Carolyn F. Jones Professor of Ophthalmology and Vice Chair for Clinical Research in the Department of Ophthalmology.   She has served on and chaired several data and safety monitoring committees and is on the editorial board of the journal Ophthalmology and Cornea. She has more than 125 publications in the areas of ophthalmology and clinical research.

Director, CPOB Coordinating Center
Phone: 215-615-1501
Fax: 215-615-1531
E-mail: maguirem@mail.med.upenn.edu