The CPOB is home to several multi-center clinical trials, serving in the capacities of the Coordinating Center or Fundus Photograph Reading Center.  For each trial, a multi-disciplinary team of professionals is assembled to provide the required expertise.

Click on the links below to learn more about CPOB Studies:

Ongoing Studies in the CPOB include:

• DREAM
• FLAME
• G-ROP

Completed multi-center studies led by CPOB:

• (CATT) The Comparison of Age-related Macular Degeneration Treatments Trials
• (e-ROP) Telemedicine Approaches to Evaluating Acute-phase Retinopathy of Prematurity Study
• (GALA) Evaluation of Alpha Lipoic Acid as a Potential Treatment for Geographic Atrophy in subjects with Age-related Macular Degeneration (GALA Study
• (MUST) The Multicenter Uveitis Steroid Treatment Trial
• (RCRIC) Retinopathy in Chronic Renal Insufficiency
• (Scleritis) Iontophoresis Delivery of Dexamethasone Phosphate for Non-infectious, Non-necrotizing Anterior Scleritis, Phase 1 Dose-varying Study
• (SITE) The Complications of Immunosuppressive Therapy for Eye Diseases Cohort Study
• (VIP-HIP)
• (CAPT) The Complications of Age-related Macular Degeneration Prevention Trial
• (VIP) Vision in Preschoolers Study
• The Choroidal Neovascularization Prevention Trial (CNVPT; 1994-2000), sponsored in part by the National Eye Institute (NEI) was a pilot randomized trial of laser photocoagulation in eyes at high risk of choroidal neovascularization secondary to age-related macular degeneration.  The CNVPT included 276 patients, 15 clinical centers, and resulted in 6 peer-reviewed publications.  THE CNVPT was the pilot study for the CAPT Study.

• Age-Related Macular Degeneration Radiotherapy Trial (AMDRT;2000-2003): CPOB staff served as the Coordinating Center for the AMDRT, an NEI sponsored pilot study to evaluate the safety and feasibility of conducting a large-scale trial of radiotherapy for eyes with neovascular AMD.  The AMDRT included 88 patients, 10 clinical centers and resulted in 3 publications.