National Institute on Drug Abuse Cocaine Collaborative Treatment Study

The National Institute on Drug Abuse (NIDA) Collaborative Cocaine Treatment Study was designed to examine the efficacy of four psychosocial treatments for cocaine dependence. This study, done between 1991 and 1997, was the largest study ever done on the treatment of cocaine dependence. To date, 41 publications have resulted from the study, which detail the study findings and conclusions. Please click here for a list of publications from the study.

The project was funded as a Cooperative Agreement involving four clinical sites, a Coordinating Center, and NIDA staff. Paul Crits-Christoph, PhD was the Principal Investigator of the Coordinating Center. The collaborating scientists at the Treatment Research Branch, Division of Clinical and Research Services at NIDA, included Jack Blaine, MD and Lisa Simon Onken, PhD. The four participating clinical sites were: University of Pennsylvania - Lester Luborsky, PhD (PI), Jacques P. Barber, PhD (CO-PI); Brookside Hospital/Harvard Medical School - Arlene Frank, PhD (PI), Stephen F. Butler, PhD (CO-PI/Innovative Training Systems); McLean/ Mass General Hospital-Harvard University Medical School- Roger D. Weiss, MD (PI), David R. Gastfriend, MD (CO-PI); University of Pittsburgh/Western Psychiatric Institute and Clinic - Michael E. Thase, MD (PI), Dennis Daley, MSW (CO-PI), Ishan M. Salloum, MD (CO-PI).

 

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