Research Interests:
My current research focuses on the microheterogeneity of human pituitary glycoprotein hormones. Synthesized and secreted human follicle stimulating hormone (FSH) and luteinizing hormone (LH) subunits and isohormones are being characterized by isoelectric point (chromatofocusing) in order to determine how physiologic changes (eg changes in hormonal status) and disease (gonadotroph cell pituitary adenomas) influence the FSH and LH secretion.

Recent Representative Publications

Benito M, Asa SL, Livolsi VA, West VA, Snyder PJ. Gonadotroph tumor associated with multiple endocrine neoplasia type 1. J Clin Endocrinol Metab. 2005 Jan;90(1):570-4.

Soares HD, Williams SA, Snyder PJ, Gao F, Stiger T, Rohlff C, Herath A, Sunderland T, Putnam K, White WF. Proteomic approaches in drug discovery and development. Int Rev Neurobiol. 2004;61:97-126. Review.

Cannizzaro M, Harel B, Reilly N, Chappell P, Snyder PJ. Voice acoustical measurement of the severity of major depression. Brain Cogn. 2004 Oct;56(1):30-5.

Harel B, Cannizzaro M, Snyder PJ. Variability in fundamental frequency during speech in prodromal and incipient Parkinson's disease: a longitudinal case study. Brain Cogn. 2004 Oct;56(1):24-9.

Kindt E, Shum Y, Badura L, Snyder PJ, Brant A, Fountain S, Szekely-Klepser G. Development and validation of an LC/MS/MS procedure for the quantification of endogenous myo-inositol concentrations in rat brain tissue homogenates. Anal Chem. 2004 Aug 15;76(16):4901-8.