Addiction Treatment and Medication Development Division
Clinical Trials
The Addiction Treatment and Medication Development Division is conducting a number of clinical trials that are on-going or soon to begin.
If you are interested in getting more information about any of these studies, please call 215-243-9959.
- Alcohol Treatment Studies
- Alcohol/Cocaine Treatment Studies
- Cocaine Treatment Studies
- Non-Treatment Studies
Study Name: Pharmacogenetic Response to Naltrexone for Alcohol Dependence
Diagnosis or Problem: Alcohol Dependence
Age: 18+ years
Study Involves: Naltrexone or placebo (double-blind) and medical management (MM) outpatient sessions for 12 weeks.
Duration: 12 weeks
Study Status: Active- Recruiting participants
For additional information or to set up a confidential screening, call
215-222-3200 ext 195 or
215-222-3200
ext 156
Study Name: Seroquel for Heavy Drinkers
Diagnosis: Alcohol Dependence
Age: 18-70
Study Involves: Seroquel or placebo (double-blind) for a period of 12 weeks plus weekly outpatient visits with a healthcare provider.
Duration: 12 weeks plus one follow-up at three months from end of treatment.
Study Status: Active- No longer recruiting participants
ALCOHOL/COCAINE TREATMENT STUDIES
Study Name: Modafinil and Naltrexone
Diagnosis or Problem: Alcohol Dependence with Cocaine Dependence
Age: 18+ years
Study Involves: Combination of two medications: Modafinil (double-blind) and Naltrexone (double-blind) or placebo(s), plus weekly cognitive behavioral therapy (CBT) and medical management (MM) outpatient visits.
Duration: 13 weeks plus follow-up visit
Study Status: Active - recruiting participants
Study Name: Vigabatrin
Diagnosis or Problem: Alcohol Dependence and Cocaine Dependence
Age: 18+
Study involves: Vigabatrin or placebo (double-blind), plus weekly cognitive behavioral therapy (CBT) and medical management (MM) outpatient visits
Duration: 8 weeks plus follow-up visit (1 month)
Study Status: Actice - recruiting participants
Study Name: Modafinil Treatment for Cocaine Dependence and HIV High-Risk Behavior (MOD 6)
Diagnosis or Problem: Cocaine Dependence
Age: 18-60 years
Study Involves: Modafinil or placebo (double-blind), plus weekly Cognitive Based Therapy and medication checks
Duration:8 weeks plus 2 follow-up visits (3 months and 6 months)
Study Status: Active - No longer recruiting participants
Study Name: Genetics of Cocaine Dependence
Diagnosis or Problem: Cocaine Dependence or Control Participants (persons with no history of substance abuse or psychiatric problems)
Age: 18 years and up
Study Involves: Subjects' participation in the study will consist of one visit during which informed consent will be obtained, research assessments will be collected, and a blood sample will be drawn. This study does not provide treatment directly.
Duration: 1 visit
Study Status: Active - recruiting participants
Study Name: Chantix Cocaine
Diagnosis or Problem: Cocaine Dependence
Age: 18-65 years
Study Involves: Varenicline (Chantix™), or placebo (double-blind), plus weekly cognitive behavioral therapy (CBT) and medical management (MM) outpatient visits.
Duration: 12 weeks plus follow-up visit (1 week later)
Study Status: Active - recruiting participants
NON-TREATMENT STUDIES
Study Name: Varenicline Cue
Diagnosis or Problem: Cocaine and Alcohol Dependence
Age: 21-65 years
Study Involves: Varenicline and placebo (double-blind), two session human laboratory study of craving in response to alcohol and cocaine cues
Duration: 6 weeks
Study Status: Active - recruiting patients
Study Name: NK1 Stress
Diagnosis or Problem: Cocaine and Alcohol Dependence
Age: 21-65 years
Study Involves: NK1 and placebo (double-blind), four session human laboratory study of craving and stress
Duration: 6 weeks
Study Status: Active - recruiting patients
Study Name: Varenicline Cocaine Reinforcement
Diagnosis or Problem: Cocaine Use
Age: 21-65 years
Study Involves: Varenicline and placebo (double-blind), two session human laboratory study of cocaine reinforcement
Duration: 6 weeks
Study Status: Active - recruiting patients
< back to Addiction Treatment main page
