Department of Psychiatry
Penn Behavioral Health

Center for Studies of Addiction

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Addiction Genetics and Pharmacogenetics Division


The Division of Addiction Genetics and Pharmacogenetics focuses on the role of genetic variation and epigenetics as factors both in the risk of addiction and as moderators of response to both psychosocial and pharmacological interventions. The Division supports research on subgroups of addicted individuals that are genetically homogeneous with respect either to the development of an addictive disorder or its response to treatment. Treatment trials supported by the Division employ state-of-the art clinical trial designs (e.g., adaptive trial designs) and genetic and epigenetic methods (including candidate gene and genomewide approaches).