The Cullen Laboratory applies Neural Engineering principles and technologies to the area of Neurotrauma.  A biomedical engineering approach is used to better understand the causative mechanisms of neural injury as well as to develop cutting-edge neural tissue engineering-based treatments to promote regeneration and restore function.



The Cullen Laboratory was founded in 2009 with significant support from the Department of Neurosurgery at the University of Pennsylvania. Our research has received additional funding from the Department of Veterans Affairs, the National Institutes of Health, the Department of Defense, the University Research Foundation at the University of Pennsylvania, and Axonia Medical, Inc.

Contact Information

D. Kacy Cullen, Ph.D
105E Hayden Hall, 3320 Smith Walk
Philadelphia, PA 19104

Apply to join the Cullen Lab



News and Events

  • The Cullen Lab and collaborators Dr. John Wolf, Dr. Misha Serruya, Dr. Brain Litt, Dr. Reuben Kraft and Dr. Isaac Chen were awarded a 3-year, $2 million dollar cooperative agreement (U01) from the NIH to further pioneer "Biological 'Living Electrodes' Using Tissue Engineered Axonal Tracts to Probe and Modulate the CNS".
  • The Cullen Lab received a 2-year grant from the U.S. Dept. of Defense to advance "Novel Tissue-Engineered Nerve Grafts for Repair of Currently Untreatable Peripheral Nerve Injury".
  • Bioengineering Ph.D. Candidate, Kritika Katiyar, was selected for a prestigious NRSA F31 Graduate Research Fellowship through the National Institutes of Health based on her proposal for "Molecular Mediators of Axon-Facilitated Axon Regeneration."
  • Dayo Adewole, a Bioengineering Ph.D. student in the Cullen Lab, was awarded a 3-year Graduate Research Fellowship through the National Science Foundation to develop next-generation neuroprosthetic interfaces. Way to go Dayo!
  • The Cullen Lab and collaborators Dr. John Duda, Dr. Isaac Chen, and Dr. John Wolf were awarded a 2-year grant from the Michael J. Fox Foundation for the project "Restoring the Nigrostriatal Pathway with Living Micro-Tissue Engineered Axonal Tracts".

View more news. →