People

Dr Cullen

Principal Investigator

D. Kacy Cullen, Ph.D.

dkacy@mail.med.upenn.edu

Ph.D., Biomedical Engineering, Georgia Institute of Technology (2005)

M.S., Mechanical Engineering, Georgia Institute of Technology (2002)

B.S., Mechanical Engineering, Georgia Institute of Technology (2000)

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Jimmy Harris

Postdoctoral Fellow

James P. Harris, Ph.D.

jamhar@mail.med.upenn.edu

Ph.D., Biomedical Engineering, Case Western Reserve University (2012)

Sc.M., Electrical Engineering, Brown University (2001)

Sc.B., Electrical Engineering, Brown University (2000)

Project: Chronic Neurodegenerative and Neurophysiological Sequela in TBI & Micro-Tissue Engineered Neural Networks to Restore Brain Circuitry

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Doctoral Candidate, Bioengineering

Laura Struzyna, B.S.E.

Predoctoral Fellowship, National Science Foundation

lstruz@mail.med.upenn.edu

B.S.E., Biomedical Engineering, Duke University (2011)

Project: Tissue Engineered Biohybrid Neuroprosthetic Interfaces, Micro-Tissue Engineered Neural Networks to Restore Brain Circuitry, Neurophysiological Assessment of Nervous System Repair

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Doctoral Candidate, Bioengineering

Kritika Katiyar, B.S.

KK343@drexel.edu

B.S., Biomedical Engineering, Drexel University (2012)

Project: Tissue Engineered Living Scaffolds for Neuroregeneration, Molecular Mechanisms of Axon-Mediated Axon Regeneration, 3-D Neural Cell Culture Techniques

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Master's Candidate, Robotics

Dayo Adewole, B.S.E.

Undergraduate Fellowship, National Science Foundation Louis-Stokes Alliance for Minority Participation (NSF/LSAMP)

oadewole@seas.upenn.edu

B.S.E., Bioengineering, University of Pennsylvania (2015)

Project: The Application of Micro-Tissue Engineered Neural Networks as Living Electrodes for Sensorimotor Information

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Research Specialist

Justin Burrell, M.S.

burrellj@mail.med.upenn.edu

M.S., Neuroscience, Tulane University (2013)

B.S., Psychology, Tulane University (2012)

Project: In Vivo Efficacy Testing of Tissue Engineered Nerve Grafts for Peripheral Nerve Injury

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Research Specialist

Dan Brown, B.S.

dbrow@mail.med.upenn.edu

B.S. Cellular and Molecular Biology, University of Michigan (2014)

Project: In Vivo Efficacy Testing of Tissue Engineered Nerve Grafts for Peripheral Nerve Injury

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Neurosurgical Resident

Dmitriy Petrov, M.D.

dmitriy.petrov@uphs.upenn.edu

M.D., Robert Wood Johnson Medical School

B.A., Biological Sciences, Rutgers University

Project: Micro-Tissue Engineered Neural Networks to Restore Brain Circuitry

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Undergraduate Students

   
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Carla Hernandez

Major: Cognitive Neuroscience and Romance Languages- Spanish and Italian (2015)

Project: Histological Techniques to Assess Neurotrauma Pathology and Repair Strategies

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Ryan Zahalka

Major: Molecular Biology (2015)

Project: Molecular Mechanisms of Axon-Mediated Axon Regeneration, Environmental Control for Bench-Top Mechano-Bioreactor

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Carla Winter

Major: Bioengineering (2016)

Project: Tissue Engineered Living Scaffolds for Neuroregeneration

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Alumni

Ellie Boyle, Undergraduate Student
Project: Tissue Engineering Strategies for Nerve Regeneration

Anthony Parisi, Undergraduate Student
Project: Quantitative Neuropathological Analyses of Rodent and Porcine Tissue Following Traumatic Brain Injury

Joseph Morand, B.S., Research Specialist
Project: In Vivo Efficacy Testing of Tissue Engineered Nerve Grafts for Peripheral Nerve Injury

Emory Kuo, M.S., Predoctoral Fellow
Project: Tissue Engineering for Neuroregeneration, Chronic Neurodegenerative and Neurophysiological Sequela in TBI

Constance Mietus, B.A., Research Specialist
Project: Neural Cell Biophysical Responses in Blast-Induced Traumatic Brain Injury

Joe Frasca, Ph.D., Post-Doctoral Fellow
Project: Chronic neurodegenerative and neurophysiological sequela of closed-head TBI

John A. Wolf, Ph.D., Post-Doctoral Fellow, University of Pennsylvania
Project: Functional Reorganization of Limbic Circuitry After TBI in Swine, Biohybridized Neural Tissue                                                                                         Engineered Constructs for Electrical Interface with Peripheral Nerve

Matthew Weingard, Medical Student, Tulane
Project: Tissue Engineering with Primary Cortical Neurons

Scott Yerganian, Bioengineering, University of Pennsylvania
Project: Mechanisms of Axon-Mediated Axon Regeneration

Janid Kiely, Biophysics, University of Pennsylvania
Project: Biomechanics of Concussion: Pathobiological Implications of Acute Cellular Damage

Arshneel Kochar, Medical Student, CWRU  
Project: Tissue Engineering Micro-Conduits for Targeted Axonal Tract Reconstruction 

Billy Lane, Pre-Med, Notre Dame
Project: Mechanisms of Axonal Degeneration in a Swine Model of Closed-Head TBI

Jonathan Yu, Biology, Haverford College
Project: Tissue Engineering Micro-Conduits for Targeted Axonal Tract Reconstruction

Contact Information

D. Kacy Cullen, Ph.D
105E Hayden Hall, 3320 Smith Walk
Philadelphia, PA 19104
dkacy@mail.med.upenn.edu

Apply to join the Cullen Lab

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News and Events

  • Dr. Cullen and colleague Dr. Douglas Smith were awarded a 3-year grant from the Department of Defense Joint Warfighter Medical Research Program to advance their work for "Repair of Segmental Nerve Defects Using Tissue-Engineered Nerve Grafts."
  • Dr. Cullen was invited to give a research talk at the Center for Translational Injury Research at the University of Texas Health Science Center in Houston, TX. He presented “Tissue Engineered Nerve Grafts for Peripheral and Central Nervous System Repair”.
  • The Cullen Lab was awarded a one-year pilot grant through the Penn Medicine Neuroscience Center to explore "Neuromodulation of Brain Circuits Using Transplantable Micro-Tissue Engineered Neural Networks."
  • James Harris, Ph.D., was awarded an NIH NRSA Postdoctoral Fellowship on the "Brain Injury Training Grant" through Penn's Center for Brain Injury & Repair. Dr. Harris' project is on "Mechanisms of Biophysical Responses and Neurodegeneration following Concomitant Blast and Inertial Traumatic Brain Injury."
  • Dr. Cullen gave a lecture at the American Society for Peripheral Nerve Annual Meeting in Kauai, Hawaii in January. The talk was titled "Tissue Engineered Grafts Accelerate Peripheral Nerve Repair By Direct Axon-Induced Axon Regeneration."
  • Laura Struzyna was a Poster Award Finalist at the Tissue Engineering and Regenerative Medicine International Society Annual Meeting in Atlanta, Georgia in November. Her poster was titled "Tissue Engineered Grafts Accelerate Peripheral Nerve Repair By Direct Axon-Induced Axon Regeneration."
  • Dr. Cullen gave an Invited Lecture at the Department of Biomedical Engineering at the Georgia Institute of Technology in May. He presented "Tissue Engineering Strategies to Restore Neural Circuitry and Create Living Scaffolds for Targeted Axonal Regeneration."
  • Dr. Cullen and collaborator Dr. Douglas Smith were awarded funding from the Department of Defense through the Rutgers - Cleveland Clinic Consortium of the Armed Forces Inst. of Regenerative Medicine. This project will investigate the efficacy of novel tissue engineered constructs encased in custom-built nerve guidance tubes to promote nerve regeneration following major peripheral nerve injury.
  • Bioengineering Ph.D. Candidate, Laura Struzyna, was selected for a prestigious 3-year Graduate Research Fellowship through the National Science Foundation based on her proposal for "Tissue Engineered Constructs for Neural Regeneration."

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