Publications
35. Meng X, Cullen DK, Tofighi MR, Rosen A. Telemetry-Based Neuromonitoring System Measuring Dynamic Intracranial Pressure Following Closed-Head Rotational Injury in Swine, IEEE Life Sciences Newsletter February (2013). LINK
34. Cullen DK and Smith DH. Bionic Connections: Living Bridges to Connect Bionic Limbs to the Nervous System. Scientific American 308(1): 52-57 (2013).
33. Ross JD, Cullen DK, LaPlaca MC, DeWeerth SP. 3-D Image Processing Techniques for Rapid Automated Segmentation of Neuronal Somata with Dense Neurite Outgrowth (in review).
32. Meng X, Bronw KD, Huang SM, Mietus CJ, Cullen DK, Tofighi MR Rosen A. Dynamic Evaluation of a Digital Wireless Intracranial Pressure Sensor for the Assessment of Traumatic Brain Injury in a Swine Model, Trans on Microwave Theory and Technology (2012). PDF
31. Cullen DK, Tang-Schomer MD, Struzyna LA, Patel AR, Johnson VE, Wolf JA, Smith DH. Micro-Tissue Engineered Constructs with Living Axons for Targeted Tract Reconstruction, Tissue Engineering Part A 18(21-22)(2012). PMID: 22702955. PDF
30. Meng X, Brown KB, Huang SM, Cullen DK, Tofighi MR, Rosen A. Dynamic Study of Wireless Intracranial Pressure Monitoring of Rotational Head Injury in Swine Model, Electronics Letters 48(7):363-364 (2012). PDF
29. Cullen DK, Browne KD, Xu Y, Adeeb S, Wolf JA, McCarron RM, Yang S, Chavko M, Smith DH. Blast-Induced Color Change in Photonic Crystals Corresponds with Brain Pathology, J Neurotrauma 28:2307-2318 (2011). PMID: 22023510. PDF
28. Cullen DK, Vernekar VN, LaPlaca MC. Trauma-Induced Plasmalemma Disruptions in 3-D Neural Cultures are Dependent on Strain Modality and Rate, J Neurotrauma 28:2219-2233 (2011). PMID: 22023556. PDF
27. Higgins AZ, Cullen DK, LaPlaca MC, Karlsson JOM. Effects of Freezing Profile Parameters on the Survival of Cryopreserved Rat Embryonic Neural Cells, J Neuroscience Methods 201(1):9-16 (2011). PMID: 21816171. PDF
26. Cullen DK and Pfister BJ. Transformative Research in Neural Engineering, Critical Reviews in Biomedical Engineering 39(3):181-183 (2011). PMID: 21967301. PDF
25. Cullen DK, Wolf JA, Smith DH, Pfister BJ. Neural Tissue Engineering for Neuroregeneration and Biohybridized Interface Microsystems In Vivo (Part 2), Critical Reviews in Biomedical Engineering 39(3):241-259 (2011). PMID: 21967304. PDF
24. Cullen DK, Wolf JA, Vernekar VN, Vukasinovic J, LaPlaca MC. Neural Tissue Engineering and Biohybridized Microsystems for Neurobiological Investigation In Vitro (Part 1), Critical Reviews in Biomedical Engineering 39(3):201-240 (2011). PMID: 21967303. PDF
23. Morrison B III, Cullen DK, LaPlaca MC. In Vitro Models for Biomechanical Studies of Neural Tissues. Neural Tissue Mechanics, L. Bilston, ed. (2011). PDF
22. Cullen DK and Pfister BJ. State of the Art and Future Challenges in Neural Engineering: Strategies for Nervous System Repair, Critical Reviews in Biomedical Engineering 39(2):79-80 (2011). PMID: 21488816. PDF
21. Pfister BJ, Gordon T, Loverde JR, Kochar AS, Mackinnon SE, Cullen DK. Biomedical Engineering Strategies for Peripheral Nerve Repair: Surgical Applications, State of the Art, and Future Challenges, Critical Reviews in Biomedical Engineering 39(2):81-124 (2011). PMID: 21488817. PDF
20. Cullen DK and Pfister BJ. State of the Art and Future Challenges in Neural Engineering: Neural Interfaces, Critical Reviews in Biomedical Engineering 39(1):1-3 (2011). PMID 21488811. PDF
19. Cullen DK, Xu Y, Reneer DV, Browne KD, Geddes JW, Yang S, Smith DH. Color Changing Photonic Crystals Detect Blast Exposure, NeuroImage 54S1:S37-S44 (2011). PMID: 21040795. Featured in Science (Editor’s Choice), Technology Review, UPI, Newsworks, Wired, The Engineer. PDF
18. Cullen DK, Gilroy ME, Irons HR, LaPlaca MC. Synapse-to-Neuron Ratio is Inversely Related to Neuronal Density in Mature Neuronal Cultures, Brain Research 1359:44-55 (2010) (cover article). PMID 20800585. PDF
17. LaPlaca MC, Vernekar VN, Shoemaker JT, Cullen DK. Three-Dimensional Neuronal Cultures. Methods in Bioengineering: 3D Tissue Engineering, Berthiaume F and Morgan J, eds. (2010). PDF
16. LaPlaca MC, Prado GR, Cullen DK, Simon CM. Plasma Membrane Damage as a Marker of Neuronal Injury, Conf Proc IEEE Eng Med Biol Soc 2009:1113-6 (2009). PMID: 19964751. PDF
15. Vukasinovic J, Cullen DK, LaPlaca MC, Glezer A. A Microperfused Incubator for Tissue Mimetic 3-D Cultures, Biomedical Microdevices 11(6):1155 (2009). PMID 19562488. PDF
14. Huang JH, Cullen DK (co-first author), Browne KD, Groff R, Zhang J, Pfister BJ, Zager EL, Smith DH. Long-Term Survival and Integration of Transplanted Engineered Nervous Tissue Constructs Promotes Peripheral Nerve Regeneration, Tissue Engineering Part A 15(7):1677-85 (2009). PMID: 19231968. PDF
13. Vernekar VN, Cullen DK, Fogleman N, Choi Y, Garcia AJ, Allen MG, Brewer GJ, LaPlaca MC. SU-8 2000 Rendered Cytocompatible for Neuronal BioMEMS Applications, J Biomed Mater Res A 89(1):138-151 (2009). PMID: 18431778. PDF
12. Cullen DK, Patel AR, Doorish JF, Smith DH, Pfister BJ. Developing a Tissue Engineered Neural-Electrical Relay Using Encapsulated Neuronal Constructs on Conducting Polymer Fibers, J Neural Engineering 5(4):374-384 (2008) (cover article). PMID: 18827311. PDF
11. Kameswaran N, Cullen DK, Pfister BJ, Ranalli NJ, Huang JH, Zager EL, Smith DH. A Novel Neuro-Prosthetic Interface with the Peripheral Nervous System Using Artificially Engineered Axonal Tracts, Neurological Res 30(10):1063-7 (2008). PMID: 19079981. PDF
10. Irons HR, Cullen DK, Shapiro NP, Lambert NA, Lee RH, LaPlaca MC. 3-D Neural Constructs: A Novel Platform for Neurophysiological Investigation, J Neural Engineering 5(3):333-341 (2008). PMID: 18756031. PDF
9. Cullen DK, Stabenfeldt SE, Simon CM, Tate CC, LaPlaca MC. In Vitro Neural Injury Model for Optimization of Tissue Engineered Constructs, J Neurosci Res 85(16):3642-51 (2007). PMID: 17671988. PDF
8. Cullen DK, Simon CM, LaPlaca MC. Strain Rate-Dependent Induction of Reactive Astrogliosis and Cell Death in 3-D Neuronal-Astrocytic Co-Cultures, Brain Res 1158:103-115 (2007) (cover article). PMID: 17555726. PDF
7. LaPlaca MC, Simon CM, Prado GR, Cullen DK. CNS Injury Biomechanics and Experimental Models, Prog Brain Res 161:13-26 (2007). PMID: 17618967. PDF
6. Cullen DK, Vukasinovic J, Glezer A, LaPlaca MC. Microfluidic Engineered High Cell Density 3-D Neural Cultures, J Neural Engineering 4(2):159-172 (2007). PMID: 17409489. Selected as “Highlights of 2007”. PDF
5. Cullen DK, Lessing MC, LaPlaca MC. Collagen-Dependent Neurite Outgrowth and Response to Dynamic Deformation in 3-D Neuronal Cultures, Ann Biomed Engineering 35(5):835-846 (2007). PMID: 17385044. PDF
4. LaPlaca MC, Prado GR, Cullen DK, Irons HR. High Rate Shear Insult Delivered to Cortical Neurons Produces Heterogeneous Membrane Permeability Alterations, Conf Proc IEEE Eng Med Biol Soc 1:2384-7 (2006). PMID: 17946956. PDF
3. Cullen DK and LaPlaca MC. Neuronal Response to High Rate Shear Deformation Depends on Heterogeneity of the Local Strain Field, J Neurotrauma 23(9):1304-1319 (2006). PMID: 16958583. PDF
2. Cullen DK, Vukasinovic J, Glezer A, LaPlaca MC. High Cell Density 3-D Neural Co-Cultures Require Continuous Medium Perfusion for Survival, Conf Proc IEEE Eng Med Biol Soc 1:636-9 (2006). PMID 17946846. PDF
1. LaPlaca MC, Cullen DK, McLoughlin JJ, Cargill RS. High Rate Shear Strain of 3-D Neural Cell Cultures: A New In Vitro Traumatic Brain Injury Model, J Biomech 38(5):1093-1105 (2005). PMID: 15797591. PDF
