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Cardiovascular Clinical Trials at Penn

The Penn CVI coordinates clinical research trials as part of its mission to advance health and accelerate the pace at which life-saving procedures, devices, and medications reach the public.

Clinical Trials Contact:
Ms. Brenda Rynn
Associate Director for Clinical Research
University of Pennsylvania Cardiovascular Division
(215) 349-8903 / cvistudy@mail.med.upenn.edu


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» Trials Administration - Restricted

The PARTNER Trial:
Placement of Aortic Transcatheter Valve

Edwards SAPIEN Transcatheter Heart Valve The purpose of this research study is to determine the safety and effectiveness of the Edwards SAPIEN Transcatheter Heart Valve device and delivery systems (transfemoral and transapical) in high risk, symptomatic patients with severe aortic stenosis. This dramatic new procedure makes no cuts in the chest at all. A catheter carrying a tissue valve as wide as a pencil is threaded up the artery from the leg to the aortic valve, where it positions the new valve over the damaged one.

This interdisciplinary study includes primary investigators from both the Cardiovascular Medicine and Cardiothoracic Surgery Divisions at Penn.

Penn’s PARTNER Contact:
Lisa Walsh, Research Nurse Coordinator
215-662-4289

PARTNER Trial - Details »
PARTNER Trial - Phila. Inquirer »
PARTNER Trial - ABC 6 News »
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