Recovery Act Awards / FY2009 Fiscal year 2009 provided an important opportunity to build translational and clinical programs through the American Recovery and Reinvestment Act of 2009 (ARRA) Stimulus program. In response to this initiative, CVI faculty members submitted 31 ARRA proposals totaling $42,563,739. To date, awards totaling $17,576,353 have been received. Remarkably, investigators participating in the CVI Complex Genetics of Cardiovascular and Metabolic Disease Initiative garnered $15,559,799 in ARRA funding. Most notable among them were RC1 awards totaling $1,999,986 and RC2 awards totaling $12,646,564 to Daniel J. Rader, MD. CVI Faculty / Cardiology Awards » CVI Faculty / Other Awards»

CVI Faculty / Cardiology Awards:

Genomics of Myocardial Transcription Factors in Cardiac Remodeling
Supplement 3-R01-HL-088577-02S1 (project period begin date: 7/1/09)
PI: Thomas Cappola
Total Awarded: $214,295

CTRIP: Genetic Testing to Individualize Management of Common Heart Diseases
RC1 – Prime: Washington University in St. Louis (project period begin date: 9/30/09)
PI: Thomas Cappola
Total Awarded: $399,886

Inflammatory Response to sleep apnea in obese subjects
Supplement 3-R01-HL-080076-04S1 (project period begin date: 7/1/09)
PI: Julio Chirinos
Total Awarded: $182,814

Genetic determinents of hypertensive heart disease in CRI
Supplement 3-R01-HL-091663-02S1 (project period begin date: 7/1/09)
PI: Daniel Dries
Total Awarded: $257,336

Validation of Microparticle Assay for Cardiovascular Disease
1-RC1-HL-099528-01 (project period begin date: 9/30/09)
PI: Emile Mohler
Total Awarded: $932,526

Molecular Basis of Myocardin Function in the Heart
1-R01-HL094520-01 (project period begin date: 7/1/09)
PI: Michael Parmacek
Total Awarded: $901,214

HDL metabolism: Influence of extracellular lipases
Supplement 3-R01-HL-055323-13S1 (project period begin date: 6/1/09)
PI: Daniel Rader
Total Awarded: $41,732

Identification of Causal Variants at Novel GWAS Loci Associated with Lipid Traits
1-RC1-HL-099793-01 (project period begin date: 9/30/09)
PI: Daniel Rader
Total Awarded: $1,000,000

Markers of the metabolic syndrome linking type 2 diabetes and MI in South Asia
1-RC1-TW-008485-01 (project period begin date: 9/30/09)
PI: Daniel Rader
Total Awarded: $999,986

Molecular mechanisms and pathways of novel genomic loci regulating plasma lipids
1-RC2-HL-101864-01 (project period begin date: 9/30/09)
PI: Daniel Rader
Total Awarded: $4,700,000

Comprehensive biomarker study to capitalize on existing GWAS in 10K South Asians
1-RC2-HL-101834-01 (project period begin date: 9/30/09)
PI: Daniel Rader
Total Awarded: $7,946,564

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CVI Faculty / Other Awards:

MR monitoring of PTC124 treatment in DMD
ARRA funding from National Institute of Arthritis and Musculoskeletal and Skin Diseases/NIH
Prime: University of Florida (project period begin date: 9/30/09)
PI: Hugh L. Sweeney
Total Awarded: $81,062

Regulated transgene expression in the retina
ARRA funding from National Eye Institute/NIH 1-RC1-EY-020274-01 (project period begin date: 9/30/09)
PI: James M. Wilson
Total Awarded: $991,039

Molecular therapy for CF and genetic diseases
Supplement 3-P30-DK-047757-16 (project period begin date: 9/02/09)
PI: James M. Wilson
Total Awarded: $159,584

DNA virus as vectors for cardiovascular diseases
Supplement 3-P01-HL-059407-10 (project period begin date: 6/01/09)
PI: James M. Wilson
Total Awarded: $28,350

A clinical trial of Aspirin and Simvastatin in pulmonary arterial hypertension
Supplement 3-R01-HL-082895-04 (project period begin date: 7/01/09)
PI: Steven Kawut
Total Awarded: $243,169

Annular and sub-valvular repair techniques for ischemic mitral regurgitation
A7023-G1 - Prime: Georgia Institute of Technology (project period begin date: 9/01/09)
PI: Joseph Gorman
Total Awarded: $120,840

Institutional clinical and translational science award
Supplement 3-UL1-RR-024134-04S2 (project period begin date: 9/17/09)
PI: Garrett Fitzgerald
Total Awarded: $607,827

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