Penn Study Finds Novel Approach May Protect Against Heart Attack Injury: Drugs target gene pathways to preserve heart, possibly other organs

Weighing the Costs of a CT Scan’s Look Inside the Heart:
NY Times Article Cites Penn's Dr. Howard Herrmann

Blood-pressure Drug Shows Promise for Marfan Patients:
Penn's chief of molecular genetics contributes to Baltimore Sun article

Lottery for Warfarin Pill Takers Could Be a Healthy Bet:
New Penn Study Examines Patient Habits Using High-Tech Pillbox

ABC World News Special Report Features Penn's Dr. Daniel Rader:
Four Steps to Lowering Your Risk for a Heart Attack

CBS 3 Health Alert on Sudden Heart Attacks:
Penn's Dr. Herrmann Comments on Effectiveness of Stress Tests

Low Blood Sodium Predicts Mortality in PAH Patients:
U.S. News and World Report Spotlights New Penn Study

Stem Cells for Heart Disease:
June 10 Public Workshop features Penn CVI Scientific Director

Drug-Eluting Stents:
Two New Penn Studies Show Drug-Eluting Stents Outperform Bare Metal Stents

Advances in Heart Valve Surgery:
Penn is Early Implant Site for New Medtronic Mitral Valve Device

Treating Coronary Heart Disease:
Adding Darapladib to statins may help prevent heart attack and stroke

Testicular Cancer and Cardiovascular Risk:
Survivors who received chemotherapy may develop endothelial injury

Reducing Racial and Ethnic Health Disparities:
Penn Receives National Grant Award for Demonstrated Interventions

A Chilling Tool Fights Cardiac Arrest:
Phila. Inquirer cites Penn's Dr. Benjamin Abella and Dr. Lance Becker

Children with ADHD should get heart tests before drug treatment:
Penn's Dr. Victoria Vetter leads AHA statement committee

Data Mining Prescribed to Ensure Drug Safety:
Penn Teams with Health Insurer on New Drug-Safety Monitoring System

Advances in Gene Therapy:
Innovative Materials Allow Better Control and Delivery via Stents

Penn Researchers Discover 'Modus Operandi' of Heart Muscle Protein:
Implications for cardiac development and health

Can Home AEDs Improve Survival?
Penn's Dr. Callans writes New England Journal of Medicine editorial on results of the Home Automated External Defibrillator (HAT) trial

Penn Experts Present Findings in New Drug Therapy and Gender Disparities at ACC Scientific Sessions

Early Warning System for Drugs: Firms Aim to Detect Heart Risks – SF Chronicle cites Penn's Dr. Garrett FitzGerald

Penn CVI Member Dr. Judd Hollander Contributes to AHA Statement: Doctors should check for cocaine use in younger patients with chest pain

Translating Molecular Discoveries into New Therapies for Atherosclerosis: Nature features article co-authored by Dr. Daniel Rader

Can You Diagnose and Treat Early Heart Failure?
ReachMD Satellite Radio Features Dr. Mariell Jessup

New Mitral Valve Repair Clinical Trial:
Penn's Dr. W. Clark Hargrove III is Lead Primary Investigator

What That Cholesterol Trial Showed, and What It Didn't – NY Times cites Penn's Dr. Daniel Rader

Common Congenital Heart Defect PDA:
Penn Researchers Identify Gene that Offers New Insights

Update: Researchers Use Magnetism to Target Cells to Animal Arteries

New Genetic Cause of Heart Attack and Vascular Disease:
Penn CVI Members Collaborate with deCode Genetics

Mapping Stem Cell Research:
WHYY Panel features Penn CVI Scientific Director

Penn Researcher Receives $3 Million to Study Molecular Cardiac Surgery

CT Scans in the Emergency Room May Save Time, Money

Penn Researcher Suggests Women Fare Worse with Some Heart Devices

PBS series "The Mysterious Human Heart" features Penn's Dr. Jessup and Dr. Rader

CVI Members Speak at Inaugural Clinical Cardiovascular Genomics Meeting

Penn Researchers Discover Novel Pathway for Increasing Good Cholesterol

Cardiac Stem Cells:
Key Pathway Linked to Heart Development and Regeneration of Damaged Heart Tissue

ICD Devices Offer Heart Patients Excellent Quality of Life > Podcast

Penn Cardiac Surgeons Implant First Temporary Total Artificial Heart in the Northeast U.S.

Claudin-5 levels are reduced in human end-stage cardiomyopathy

Antiplatelet Therapy in Acute Coronary Syndromes: The Emergency Physician's Perspective

CD44 expressed on both bone marrow-derived and non-bone marrow-derived cells promotes atherogenesis in ApoE-deficient mice

Adults with genetic syndromes and cardiovascular abnormalities: clinical history and management

Comparison of matrix metalloproteinase 9 and brain natriuretic peptide as clinical biomarkers in chronic heart failure

Hyponatremia predicts right heart failure and poor survival in pulmonary arterial hypertension

Ultrasound Detection of Increased Carotid Intima-Media Thickness and Carotid Plaque in an Office Practice Setting: Does It Affect Physician Behavior or Patient Motivation?

Ablation of Atrial Fibrillation in the Setting of Hypertrophic Cardiomyopathy

Beyond high-density lipoprotein cholesterol levels evaluating high-density lipoprotein function as influenced by novel therapeutic approaches

Acute myocardial infarction requiring mechanical bridge to transplantation in a patient with undiagnosed anti-phospholipid antibody syndrome

Neurologic Outcomes from High Risk Descending Thoracic and Thoracoabdominal Aortic Operations in the Era of Endovascular Repair

A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration

Safety, pharmacokinetics, and pharmacodynamics of oral apoA-I mimetic peptide D-4F in high-risk cardiovascular patients

Cardiovascular risk in long-term survivors of testicular cancer

Site-Specific Atherogenic Gene Expression Correlates With Subsequent Variable Lesion Development in Coronary and Peripheral Vasculature

A comparison of bare-metal and drug-eluting stents for off-label indications

The effect of darapladib on plasma lipoprotein-associated phospholipase A2 activity and cardiovascular biomarkers in patients with stable coronary heart disease or coronary heart disease risk equivalent: the results of a multicenter, randomized, double-blind, placebo-controlled study

Caveat emptor: the need for evidence, regulation, and certification of home telehealth systems for the management of chronic conditions

Long-Term Clinical Efficacy and Risk of Catheter Ablation for Atrial Fibrillation in the Elderly

Cardiac retransplantation is an efficacious therapy for primary cardiac allograft failure

Reduced effects of BAY K 8644 on L-type Ca2+ current in failing human cardiac myocytes are related to abnormal adrenergic regulation

A House with Many Rooms: How the Heart Got its Chambers with Foxn4

Antigenic stimulation in the simian model of HIV infection yields dilated cardiomyopathy through effects of TNFalpha

Wnt signaling: an essential regulator of cardiovascular differentiation, morphogenesis and progenitor self-renewal

Atrial Fibrillation Catheter Ablation: Learning by Burning Continues

Clinical utility of automated assessment of left ventricular ejection fraction using artificial intelligence-assisted border detection

Trends in the use of percutaneous closure of patent foramen ovale and atrial septal defect in adults, 1998-2004

Translating Molecular Discoveries into New Therapies for Atherosclerosis

Myocardin regulates expression of contractile genes in smooth muscle cells and is required for closure of the ductus arteriosus in mice

The multifaceted role of Notch in cardiac development and disease

A common variant on chromosome 9p21 affects the risk of myocardial infarction

Penn Heart Failure Study»
Certain genes may make some patients more likely to develop heart failure. This trial searches for genes that may contribute to heart failure.

CURE–AF »
This study evaluates the safety and effectiveness of the Medtronic Cardioblate© Surgical Ablation System at reestablishing the normal heart rhythm in patients with permanent Atrial Fibrillation (AF) or persistent AF who require open heart surgery using the modified Cox Maze III procedure for an existing heart condition.

Atherosclerosis in Chronic Kidney Disease »
Gen-CRIC (Chronic Renal Insufficiency Cohort) is a genetic study of inflammatory, metabolic, and cardiovascular (CVD) outcomes in patients with mild-moderate chronic kidney disease (CKD).

Penn Diabetes Heart Study »
This study evaluates new risk factors related to heart disease in persons and families with type II diabetes.

Heart Failure Exercise Training »
Certain patients with heart disorders may benefit from exercise in terms of physical fitness, sense of well being and better qualtity of life.

Human Heart Tissue Protocol »
Studies done under this protocol are designed to help us understand the causes and manifestations of human heart failure. Participants will include people receiving a heart transplant or a left ventricular mechanical cardiac assist device (LVAD).

Outpatient Coronary Stent Study »
The study will compare standard observation in the hospital after angioplasty and stenting with early discharge 2 to 4 hours after the procedure, in terms of patient satisfaction and preference, and safety.

View All Trials »