Penn CVI Faculty Members
The Penn CVI has over 180 faculty members based in 17 different departments within the Perelman School of Medicine
and other schools at Penn such as Engineering
and Veterinary Medicine.
The CVI is made up of seven interdisciplinary research programs
designed to promote collaboration between basic, translational, and clinical investigators.
Research Programs
The Congenital Heart Disease / Development research program unit focuses on genetic, molecular and translational research and teaching relevant to
our further understanding of the etiology of developmental cardiovascular malformations. Activities in this arena will contribute directly to the
understanding and treatment of congenital heart disease in both pediatric and adult populations and to the elucidation of basic mechanisms of cardiac,
endothelial and vascular smooth muscle development and function.
The Prevention, Atherosclerosis, Lipids research program unit in the CVI is focused on the pathogenesis of atherosclerosis and acute coronary syndromes and the risk factors
involved in their development. Its major focus is to bring together investigators and clinicians within CVI who are interested in this area in order to facilitate basic, translational, and clinical research.
The myocyte biology and heart failure research program unit is focused on elucidating the pathophysiology of myocardial remodeling and the syndrome of congestive heart failure.
This program unit encompasses basic, translational and clinical research activities performed by individuals and teams from a variety of disciplines.
Together these components are designed to encourage and facilitate inquiries elucidating the genetic and environmental mechanisms contributing to variations in disease progression,
clinical manifestations and therapeutic responses observed in patients with heart failure.
The Penn EP faculty at HUP have been internationally recognized for their
pioneering efforts in electrophysiology. More than a dozen major advances in the diagnosis and treatment of arrhythmias developed at Penn have been adapted by the EP community worldwide.
To ensure the highest standards of care for patients with heart rhythm disorders, Penn has embarked on a
dramatic expansion of its EP treatment facilities and equipment. The EP program now has five EP procedure rooms
equipped with intracardiac echo imaging, computerized mapping systems and rotational angiography technology.
The Pulmonary Vascular Disease Program is focused on understanding the mechanisms of a variety of diseases characterized by
pulmonary vascular dysfunction and the subsequent effects on the right side of the heart.
This program includes researchers and clinicians from various disciplines, including pulmonary, cardiology, pathology, developmental and cell biology, radiology, surgery, biostatistics, and genetics.
Extensive experience in cellular physiology, cardiovascular function, electrophysiology, high-throughput genetics, epidemiology, biostatistics, clinical trials, and
clinical care of patients with a variety of pulmonary vascular diseases and/or right heart failure enables the translation of research questions concerning health and disease into feasible studies.
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