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Publications

Below find a sampling of Penn CVI Member publications.
Each links to an abstract in PubMed, the U.S. National Library of Medicine.

Archives: 2007 / 2006 / 2005

NIH Policy on Public Access / Important Dates / Links

2008

August
Ventricular arrhythmias in normal hearts
July
CD44 expressed on both bone marrow-derived and non-bone marrow-derived cells promotes atherogenesis in ApoE-deficient mice
Claudin-5 levels are reduced in human end-stage cardiomyopathy
Antiplatelet Therapy in Acute Coronary Syndromes: The Emergency Physician's Perspective
June
Preferences for cardiac tests and procedures may partially explain sex but not race disparities
Essentials of restenosis for the interventional cardiologist
Comparison of matrix metalloproteinase 9 and brain natriuretic peptide as clinical biomarkers in chronic heart failure
Can we improve upon human performance in the electrophysiology laboratory?
Ablation of Atrial Fibrillation in the Setting of Hypertrophic Cardiomyopathy
Ultrasound Detection of Increased Carotid Intima-Media Thickness and Carotid Plaque in an Office Practice Setting: Does It Affect Physician Behavior or Patient Motivation?
A small molecule for a large disease (Marfan Syndrome)
Adults with genetic syndromes and cardiovascular abnormalities: clinical history and management
Hyponatremia predicts right heart failure and poor survival in pulmonary arterial hypertension
A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration
Beyond high-density lipoprotein cholesterol levels evaluating high-density lipoprotein function as influenced by novel therapeutic approaches
Acute myocardial infarction requiring mechanical bridge to transplantation in a patient with undiagnosed anti-phospholipid antibody syndrome
Persistent expression of Pax3 in the neural crest causes cleft palate and defective osteogenesis in mice
Safety, pharmacokinetics, and pharmacodynamics of oral apoA-I mimetic peptide D-4F in high-risk cardiovascular patients
Differences in the patterns of health care system distrust between blacks and whites
Foxp2 inhibits Nkx2.1-mediated transcription of SP-C via interactions with the Nkx2.1 homeodomain
Caveat emptor: the need for evidence, regulation, and certification of home telehealth systems for the management of chronic conditions
Heart Rhythm Society/Pediatric and Congenital Electrophysiology Society Clinical Competency Statement: training pathways for implantation of cardioverter-defibrillators and cardiac resynchronization therapy devices in pediatric and congenital heart patients
Novel exon 12 mutations in the HIF2A gene associated with erythrocytosis
Control of Endothelial Targeting and Intracellular Delivery of Therapeutic Enzymes by Modulating the Size and Shape of ICAM-1-targeted Carriers
Analysis of the spatial and temporal characteristics of platelet-delivered factor VIII-based clots
Diagnostic E-codes for commonly used, narrow therapeutic index medications poorly predict adverse drug events
May
Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia
Microsomal prostaglandin E synthase-1 inhibition in cardiovascular inflammatory disease
EBV PCR in the diagnosis and monitoring of posttransplant lymphoproliferative disorder: results of a two-arm prospective trial
Improving in-hospital cardiac arrest process and outcomes with performance debriefing
Facilitated PCI in patients with ST-elevation myocardial infarction
Medical management of Marfan syndrome
Cardiovascular risk in long-term survivors of testicular cancer
Long-term outcomes after Fontan surgery
Long-Term Clinical Efficacy and Risk of Catheter Ablation for Atrial Fibrillation in the Elderly
Cardiac retransplantation is an efficacious therapy for primary cardiac allograft failure
Cardiovascular monitoring of children and adolescents with heart disease receiving stimulant drugs:
A scientific statement from the American Heart Association Council on Cardiovascular Disease in the Young Congenital Cardiac Defects Committee and the Council on Cardiovascular Nursing
Reduced effects of BAY K 8644 on L-type Ca2+ current in failing human cardiac myocytes are related to abnormal adrenergic regulation
Exogenous cytochrome C restores myocardial cytochrome oxidase activity into the late phase of sepsis
A membrane-based microfluidic device for controlling the flux of platelet agonists into flowing blood
Blacks and whites have a similar prevalence of reduced left ventricular ejection fraction in the general population: the Dallas Heart Study (DHS)
Intra-arrest cooling with delayed reperfusion yields higher survival than earlier normothermic resuscitation in a mouse model of cardiac arrest
EBV PCR in the diagnosis and monitoring of posttransplant lymphoproliferative disorder: results of a two-arm prospective trial
Microsomal prostaglandin E synthase-1 inhibition in cardiovascular inflammatory disease
The Impact of Concordant and Discordant Conditions on the Quality of Care for Hyperlipidemia
Characterization and properties of pre beta-HDL particles formed by ABCA1-mediated cellular lipid efflux to apoA-I
Cytometric fingerprinting: quantitative characterization of multivariate distributions
Characterization and properties of pre beta-HDL particles formed by ABCA1-mediated cellular lipid efflux to apoA-I
Development of a vessel-simulating flow-through cell method for the in vitro evaluation of release and distribution from drug-eluting stents
Caveolae are an essential component of the pathway for endothelial cell signaling associated with abrupt reduction of shear stress
Neurologic Outcomes from High Risk Descending Thoracic and Thoracoabdominal Aortic Operations in the Era of Endovascular Repair
Heart failure: hemodynamic assessment using echocardiography
Factor VIII accelerates proteolytic cleavage of von Willebrand factor by ADAMTS13

April

Canonical notch signaling is dispensable for the maintenance of adult hematopoietic stem cells

Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy

Cre reporter mouse expressing a nuclear localized fusion of GFP and beta-galactosidase reveals new derivatives of Pax3-expressing precursor

Myocardial perfusion defect caused by intramyocardial lipoma

Reciprocal regulation of the Ca2+ and H+ sensitivity in the SLO1 BK channel conferred by the RCK1 domain

The effect of darapladib on plasma lipoprotein-associated phospholipase A2 activity and cardiovascular biomarkers in patients with stable coronary heart disease or coronary heart disease risk equivalent: the results of a multicenter, randomized, double-blind, placebo-controlled study

The influence of pravastatin and atorvastatin on markers of oxidative stress in hypercholesterolemic humans

Epidemiologic features of the presentation of critical congenital heart disease: implications for screening

Implications of preoperative heart failure: the next frontier in perioperative medicine?

A novel locus for dilated cardiomyopathy maps to canine chromosome 8

Effect of unrelated comorbid conditions on hypertension management

Sexual behavior and reproductive concerns among adolescents and young adults with congenital heart disease

Deep sedation for cardiac magnetic resonance imaging: a comparison with cardiac anesthesia

Preliminary experience with the smooth muscle troponin-like protein, calponin, as a novel biomarker for diagnosing acute aortic dissection

Can Home AEDs Improve Survival?

Bifunctional role of Rev-erbalpha in adipocyte differentiation

Warfarin therapy: in need of improvement after all these years

Deep sedation for cardiac magnetic resonance imaging: a comparison with cardiac anesthesia

Tumoricidal activity of high-dose tumor necrosis factor-alpha is mediated by macrophage-derived nitric oxide burst and permanent blood flow shutdown

Platelet-delivered factor VIII provides limited resistance to anti-factor VIII inhibitors

March

Oxidation of multiple methionine residues impairs rapid sodium channel inactivation

The RCK1 high-affinity Ca2+ sensor confers carbon monoxide sensitivity to Slo1 BK channels

Effects of cardiac resynchronization therapy on ventricular remodeling

Complex Fractionated Electrogram Distribution and Temporal Stability in Patients Undergoing Atrial Fibrillation Ablation

Ventricular Tachycardia Storm After Initiation of Biventricular Pacing: Incidence, Clinical Characteristics, Management, and Outcome

ACCF/ASE/ACEP/AHA/ASNC/SCAI/SCCT/SCMR 2008 appropriateness criteria for stress echocardiography: a report of the American College of Cardiology Foundation Appropriateness Criteria Task Force

Randomized controlled trial of an implantable continuous hemodynamic monitor in patients with advanced heart failure: the COMPASS-HF study

Management of Cocaine-Associated Chest Pain and Myocardial Infarction. A Scientific Statement From the American Heart Association Acute Cardiac Care Committee of the Council on Clinical Cardiology

Computer-Assisted Segmentation of White Matter Lesions in 3D MR Images Using Support Vector Machine

A house with many rooms: how the heart got its chambers with foxn4

Cardiovascular risk in long-term survivors of testicular cancer

Wnt signaling: an essential regulator of cardiovascular differentiation, morphogenesis and progenitor self-renewal

Transcription factor KLF2 regulates the migration of naive T cells by restricting chemokine receptor expression patterns

Antigenic stimulation in the simian model of HIV infection yields dilated cardiomyopathy through effects of TNFalpha

Clinical utility of automated assessment of left ventricular ejection fraction using artificial intelligence-assisted border detection

Atrial Fibrillation Catheter Ablation: Learning by Burning Continues

Safety, pharmacokinetics and pharmacodynamics of a single dose of oral apolipoprotein A-I mimetic peptide D-4F in high-risk cardiovascular patients

Predictors of atrial arrhythmias after device closure of secundum type atrial septal defects in adults

The safety and efficacy of thrombolysis for strokes after cardiac catheterization.

Contributions of the Carboxyl-Terminal Helical Segment to the Self-Association and Lipoprotein Preferences of Human Apolipoprotein E3 and E4 Isoforms.

Novel therapeutic targets at the platelet vascular interface

Transcatheter treatment for systemic-to-pulmonary artery shunt obstruction in infants and children

February

Management of lipids in the prevention of cardiovascular events

New Strategies for Cardiopulmonary Resuscitation

Trends in the use of percutaneous closure of patent foramen ovale and atrial septal defect in adults, 1998-2004

Functional block in the posterior left atrium another piece in the puzzle of atrial fibrillation initiation

Translating Molecular Discoveries into New Therapies for Atherosclerosis

Currying Favor for the Heart

Diagnosing subtle forms of potentially life-threatening diseases

Percutaneous transcatheter closure of patent foramen ovale with the Amplatzer Cribriform septal occluder

Site-Specific Atherogenic Gene Expression Correlates With Subsequent Variable Lesion Development in Coronary and Peripheral Vasculature

Myocardin regulates expression of contractile genes in smooth muscle cells and is required for closure of the ductus arteriosus in mice

Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development

Transmyocardial revascularization to enhance myocardial vasculogenesis and hemodynamic function

ECG clues for diagnosing ventricular tachycardia mechanism

Cardiovascular late effects and the ongoing care of adult cancer survivors

Noninvasive assessment of myocardial viability in a small animal model:
Comparison of MRI, SPECT, and PET

Single procedure efficacy of isolating all versus arrhythmogenic pulmonary veins on long-term control of atrial fibrillation: A prospective randomized study

Management of Lipids in the Prevention of Cardiovascular Events

EBV PCR in the Diagnosis and Monitoring of Posttransplant Lymphoproliferative Disorder: Results of a Two-Arm Prospective Trial

Hyperemic Flow Heterogeneity within the Calf, Foot, and Forearm Measured with Continuous Arterial Spin Labeling MRI

Prophylactic thrombolysis by thrombin-activated latent prourokinase targeted to PECAM-1 in the pulmonary vasculature

Evaluation of coverage variation of SNP chips for genome-wide association studies

Characterization and properties of prebeta-HDL particles formed by ABCA1-mediated cellular lipid efflux to ApoA-I

Social support and self-care of patients with heart failure

January

A comparison of bare-metal and drug-eluting stents for off-label indications

Clinical Exacerbations as a Surrogate End Point in Heart Failure Research

Molecular Remodeling in Human Heart Failure

A Comparison of Bare-metal and Drug-eluting Stents for Off-label Indications

Immobilization of plasmid DNA on an anti-DNA antibody modified coronary stent for intravascular site-specific gene therapy

Reduced Nitric Oxide Causes Age-Associated Impairment of Circadian Rhythmicity

Endothelial Lipase Is Increased In Vivo by Inflammation in Humans

Improving Medication Compliance in Patients with Heart Failure

Failure of digital echocardiography to accurately diagnose intracardiac shunts

The Multifaceted Role of Notch in Cardiac Development and Disease

Blood is Thicker than Lymph

Endothelial targeting of semi-permeable polymer nanocarriers for enzyme therapies

Peripheral circadian clock rhythmicity is retained in the absence of adrenergic signaling

Incidence and prevalence of abnormal liver associated enzymes in patients with atrial fibrillation in a routine clinical care population

Extracardiac features predicting 22q11.2 Deletion Syndrome in adult congenital heart disease

Arterial tortuosity syndrome: clinical and molecular findings in 12 newly identified families

A placebo controlled, dose-ranging, safety study of allogenic mesenchymal stem cells injected by endomyocardial delivery after an acute myocardial infarction

2007

A Rewarming Maneuver Demonstrates the Contribution of Blood Flow to Electrode Cooling During Internally Irrigated RF Ablation

Time and Temperature Profile of Catheter Cryoablation of Right Septal and Free Wall Accessory Pathways in Children

Rev-erbalpha, a heme sensor that coordinates metabolic and circadian pathways

N-cadherin haploinsufficiency affects cardiac gap junctions and arrhythmic susceptibility

Ablation of ventricular tachycardia

Should my outpatient center have a beta-blocker protocol?

GATA4 sequence variants in patients with congenital heart disease

Ventricular restraint prevents infarct expansion and improves borderzone function after myocardial infarction: a study using magnetic resonance imaging, three-dimensional surface modeling, and myocardial tagging

Liver x receptor and farnesoid x receptor as therapeutic targets.

Fate of the residual distal and proximal aorta after acute type a dissection repair using a contemporary surgical reconstruction algorithm

Obesity is a common comorbidity in children with congenital and acquired heart disease

Aging is associated with myocardial insulin resistance and mitochondrial dysfunction

Creation of a coronary sinus to atrial communication in coronary sinus ostial atresia improves cardiac function after Fontan

Emergency extracorporeal life support for asphyxic status asthmaticus

NF1 Regulates a Ras-Dependent Vascular Smooth Muscle Proliferative Injury Response

Menin is required in cranial neural crest for palatogenesis and perinatal viability

The pro-angiogenic cytokine pleiotrophin potentiates cardiomyocyte apoptosis through inhibition of endogenous AKT/PKB activity

Guidelines for the management of heart failure: differences in guideline perspectives

Endothelial Transcriptome Profiles In Vivo in Complex Arterial Flow Fields

COX-2 Inhibitors and Cardiovascular Risk

Noncontact frequency mapping of atrial fibrillation: are we ready to accept "virtual" mapping?

Site-specific twelve-lead ECG features to identify an epicardial origin for left ventricular tachycardia in the absence of myocardial infarction

Tetranor PGDM: An abundant urinary metabolite reflects biosynthesis of PGD2 in mice and humans

Management of Lipids in the Prevention of Cardiovascular Events

Notch signaling in vascular smooth muscle cells is required to pattern the cerebral vasculature

The Surgical Treatment of End-stage Heart Failure

Echocardiographic guidance and assessment of percutaneous repair for mitral regurgitation with the Evalve MitraClip: lessons learned from EVEREST I

Mitral valve tenting index for assessment of subvalvular remodeling

Incidence and prevalence of abnormal liver associated enzymes in patients with atrial fibrillation in a routine clinical care population

Identification of a new functional splice variant of the enzyme methionine sulphoxide reductase A (MSRA) expressed in rat vascular smooth muscle cells

Gaps in public knowledge of peripheral arterial disease: the first national PAD public awareness survey

Mitochondrial Resuscitation with Exogenous Cytochrome C in the Septic Heart

Determinants of coronary artery calcification progression in renal transplant recipients

Adherence to warfarin assessed by electronic pill caps, clinician assessment, and patient reports: results from the IN-RANGE study

Antifibrinolytic use in adult cardiac surgery

American Society of Clinical Oncology clinical evidence review on the ongoing care of adult cancer survivors: cardiac and pulmonary late effects

Surface electrocardiogram characteristics of atrial tachycardias occurring after pulmonary vein isolation

Hepatic Proprotein Convertases Modulate HDL Metabolism

Atrial fibrillation is common after ablation of isolated atrial flutter during long-term follow-up

Factors Associated with the Development of Expertise in Heart Failure Self-Care

Wnt/ß-catenin signaling promotes expansion of Isl-1–positive cardiac progenitor cells through regulation of FGF signaling

Rapid Cooling for Saving Lives: A Bioengineering Opportunity

Peripheral Circadian Clocks in the Vasculature

Magnetically Driven Plasmid DNA Delivery with Biodegradable Polymeric Nanoparticles

Cardiovascular function in normotensive offspring of persons with essential hypertension and black race

Hypercholesterolemia suppresses Kir channels in porcine bone marrow progenitor cells in vivo

Gene transfer of wild-type apoA-I and apoA-I Milano reduce atherosclerosis to a similar extent

Obesity and Atherogenic Dyslipidemia

Quality of Life Among Implantable Cardioverter-defibrillator (ICD) Recipients

Corin I555(P568) allele is associated with enhanced cardiac hypertrophic response to increased systemic afterload

Electron-beam Computerized Tomography Correlates with Coronary Angiogram in Chronic Kidney Disease Patients

Myocardin-Related Transcription Factors: Critical Coactivators Regulating Cardiovascular Development and Adaptation

Hdac2 Regulates the Cardiac Hypertrophic Response by Modulating Gsk3 Beta Activity

Prognosis following Acute Myocardial Infarction: insights from cardiovascular magnetic resonance

An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation

Characteristics of patients undergoing atrial fibrillation ablation: trends over a seven-year period 1999-2005

CXCL16 is a Marker of Inflammation, Atherosclerosis, and Acute Coronary Syndromes in Humans

Inhibition of Microsomal Triglyceride Transfer Protein in Familial Hypercholesterolemia

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2006

Klf2 Is an Essential Regulator of Vascular Hemodynamic Forces In Vivo

Fluorescence Spectroscopy and Imaging of Myocardial Apoptosis

Imaging Stem Cells Implanted in Infarcted Myocardium

Bedside Tool for Predicting Risk of Postoperative Dialysis in Patients Undergoing Cardiac Surgery

Transcriptional genomics associates FOX transcription factors with human heart failure

Robotic Cardiac Surgery

Mitral Valve Surgery in Heart Failure: Insights from the Acorn Clinical Trial

Role of Homeodomain-only Protein in the Cardiac Conduction System

Mesenchymal Stem Cell Injection After Myocardial Infarction

» Top

2005

Resynchronization Therapy in Pediatric and Congenital Heart Disease Patients: an international multicenter study

Cardiac Neural Crest

Efficient myocyte gene delivery with complete cardiac surgical isolation in situ

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NIH Policy on Public Access and Research Publications
NIH Public Access Policy Goes Into Effect April 7, 2008:
On January 11, 2008, the National Institutes of Health (NIH) announced a revision to its Public Access Policy. The policy now *requires* eligible researchers to deposit copies of final manuscripts upon acceptance into a peer-reviewed journal so that they may be made publicly available within 12 months of publication. This policy applies to any journal articles resulting from research supported in whole or in part by direct funds from NIH.

Important Dates
April 7, 2008
All articles arising from NIH funds must be submitted to PubMed Central upon acceptance for publication.
May 25, 2008
NIH applications, proposals, and progress reports must include the PubMed Central reference number when citing an article that falls under the policy and is authored or co-authored by the investigator, or arose from the investigator’s NIH award. This policy includes applications submitted to the NIH for the May 25, 2008 due date and subsequent due dates.

Helpful Links:
NIH Public Access Home Page »
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