Cardiovascular Research at Penn… Building Bridges, Accelerating Discovery, Advancing Care
The Penn Cardiovascular Institute (Penn CVI) leverages the expertise and resources of scientists and clinicians across the
Penn Campus and Health System to generate research targeted to treat and cure heart and vascular disease.
The Penn CVI is organized into seven research programs bridging basic science and clinical investigation to better promote interdisciplinary research.
Research Pipeline… Genetics and Personalized Medicine
Penn Complex Genetics Initiative / Cardiovascular DNA Bank »
Some rare diseases are caused by a single change in one gene while other common diseases like obesity, coronary artery disease, and diabetes may be caused by several genes working together. The Complex Genetics Initiative hopes to learn about the genetic causes of these diseases and how different people respond to medications and treatments.
The Genetics of Cardiovascular and Metabolic Phenotypes Study
seeks to identify genes involved in complex cardiovascular disorders by developing a DNA bank. Over the next five years 100,000 adult volunteers seeking clinical care at the
University of Pennsylvania Health System (UPHS) will be invited to join the study.
Two Penn researchers, along with scientists from the Fred Hutchinson Cancer Research Center,
have been awarded $16.7 million from the National Heart Lung Blood Institute (NHLBI) for collaborative stem cell research projects.
This funding represents part of a larger $170 million effort to create the NHLBI Progenitor Cell Biology Consortium
which will bring together researchers from the heart, lung, blood, and technology research fields. The consortium assembles nine research hubs with multidisciplinary teams of
principal investigators to focus on progenitor cell biology.
NIH Projects »
Clinical Trials »
Publications »
