PennOmics is Penn’s new translational research data warehouse, integrating research and clinical data from Penn Data Store (PDS), the Cancer Center tumor registry, the Velos CTMS and genomics data from contributing clinical and research labs throughout UPHS and the school of medicine. The user interface, cohort explorer, allows researchers and clinicians to access clinical and contributed research data on 3.6 million patients via a web browser. They are able to ask questions of the data and formulate hypotheses. The data in PennOmics has been de-identified meaning all direct patient identifiers have been removed. Users may gain access to the data by signing a data use agreement. Data can be exported from PennOmics for further analysis directly by researchers/clinicians or a request can be made for additional data available in PDS.