David J.E. Kast, Ph.D.

PostDoctoral Fellow
Ph.D. 2010 - University of Minnesota, Biophysics

E-mail: kast at mail . med . upenn . edu

Phone: (215) 573-0983

Selected Publications

Thomas DD, Muretta JM, Colson BA, Mello R, Kast DJ. (2011) Spectroscopic probes of muscle proteins. Comprehensive Biophysics, chapter 4.15. Elsevier, in press.

Kast DJ & Dominguez R. (2011) Arp you ready for actin in the nucleus? EMBO J. 30:2097-2098

Muretta JM, Kyrychenko A, Ladokhin AS, Kast DJ, Gillispie GD, Thomas DD. (2010) High-performance time-resolved fluorescence by direct waveform recording. Rev Sci Instrum. 81:103101

Kast D, Espinoza-Fonseca LM, Yi C, Thomas DD. (2010) Phosphorylation-induced structural changes in smooth muscle myosin regulatory light chain. PNAS 107:8207-8212

Thomas DD, Kast D, Korman VL. (2009) Site-directed spectroscopic probes of actomyosin structural dynamics. Annu Rev Biophys. 38:347-369

Espinoza-Fonseca LM, Kast D, Thomas DD. (2008) Thermodynamic and structural basis of phosphorylation-induced disorder-to-order transition in the regulatory light chain of smooth muscle myosin. J Am Chem Soc. 130:12208-12209

Espinoza-Fonseca LM, Kast D, Thomas DD. (2007) Molecular dynamics simulations reveal a disorder-to-order transition on phosphorylation of smooth muscle myosin. Biophys J. 93:2083-2090