Grzegorz Rebowski, Ph.D.

Research Specialist
Ph.D (2002) Polish Academy of Sciences. Organic Chemistry.

Email: rebowski at mail . med . upenn . edu
Phone: (215) 573-0983

Publications

Namgoong S, Boczkowska M, Glista MJ, Winkelman JD, Rebowski G, Kovar DR, Dominguez R (2011) Mechanism of actin filament nucleation by Vibrio VopL and implications for tandem-W domain nucleation. Nature Struct Mol Biol 18: 1060-1067

Jansen S, Collins A, Yang C, Rebowski G, Svitkina T*, Dominguez R* (2011) Mechanism of Actin Filament Bundling by Fascin. J Biol Chem 268: 30087-30096

Pykalainen A, Boczkowska M, Zhao H, Saarikangas J, Rebowski G, Jansen M, Hakanen J, Koskela E, Peranen J, Vihinen H, Jokitalo E, Salminen M, Ikonen E, Dominguez R*, Lappalainen P* (2011) Pinkbar is an epithelial-specific BAR domain protein that generates planar membrane structures. Nature Struct Mol Biol 18: 902-907

Rebowski G, Namgoong S, Boczkowska M, Leavis P, Navaza J, Dominguez R (2010) Structure of a Longitudinal Actin Dimer Assembled by Tandem W Domains - Implications for Actin Filament Nucleation. J Mol Biol 403:11-23

Rebowski G.,* Boczkowska M.,* Hayes D.B., Guo L., Irving T.C. & Dominguez R. (2008). X-ray scattering study of actin polymerization nuclei assembled by tandem Wdomains. PNAS 105:10785-10790.

Boczkowska M*, Rebowski G*, Petoukhov MV, Hayes DB, Svergun DI, Dominguez R. X-ray scattering study of activated Arp2/3 complex with bound actin-WCA. Structure. 2008 16:695-704.

Chereau D, Boczkowska M, Skwarek-Maruszewska A, Fujiwara I, Hayes DB, Rebowski G, Lappalainen P, Pollard TD, Dominguez R. (2008). Leiomodin is an actin filament nucleator in muscle cells. Science., 320:239-243.

Ferron F, Rebowski G, Lee SH, Dominguez R. Structural basis for the recruitment of profilin-actin complexes during filament elongation by Ena/VASP. EMBO J. 2007 26:4597-4606.

Lee SH, Hayes DB, Rebowski G, Tardieux I, Dominguez R. Toxofilin from Toxoplasma gondii forms a ternary complex with an antiparallel actin dimer. PNAS 2007 104:16122-16127.

Terrak M*, Rebowski G*, Lu RC, Grabarek Z, Dominguez R. Structure of the light chain-binding domain of myosin V. PNAS, 102:12718-12723.

Nawrot B, Antoszczyk S, Maszewska M, Rebowski G, Kuwabara T, Warashina M, Taira K, Stec WJ, (2002). Modulation of beta-secretase gene expression by action of catalytic nucleic acids. Nucleic Acids Res Suppl., (2):105-6.

Niewiarowski W, Gendaszewska E, Rebowski G, Wójcik M, Mikołajczyk B, Goss W, Soszyński M, Bartosz G. (2000). Multidrug resistance-associated protein--reduction of expression in human leukaemia cells by antisense phosphorothioate olignucleotides. Acta Biochim Pol, 47(4):1183-8.

Rebowski G, Wójcik M, Boczkowska M, Gendaszewska E, Soszyński M, Bartosz G, Niewiarowski W, (2001). Antisense hairpin loop oligonucleotides as inhibitors of expression of multidrug resistance-associated protein 1: their stability in fetal calf serum and human plasma. Acta Biochim Pol, 48(4):1061-76.

Kanagaratnam R, Misiura K, Rebowski G, Ramasamy R, (1998). Malaria merozoite surface protein antisense oligodeoxynucleotides lack antisense activity but function as polyanions to inhibit red cell invasion. Int J Biochem Cell Biol, 30(9):979-85.

Zielińska E, Niewiarowski W, Bodalski J, Rebowski G, Skretkowicz J, Mianowska K, Sekulska M, (1998). Genotyping of the arylamine N-acetyltransferase polymorphism in the prediction of idiosyncratic reactions to trimethoprim-sulfamethoxazole in infants. Pharm World Sci, 20(3):123-30.

Zielińska E, Niewiarowski W, Bodalski J, Stańczyk A, Bolanowski W, Rebowski G, (1997). Arylamine N-acetyltransferase (NAT2) gene mutations in children with allergic diseases. Clin Pharmacol Ther, Dec;62(6):635-42.

Ramasamy R, Kanagaratnam R, Misiura K, Rebowski G, Amerakoon R, Stec WJ, (1996) Anti-sense oligodeoxynucleoside phosphorothioates nonspecifically inhibit invasion of red blood cells by malaria parasites. Biochem. Biophys. Res. Commun, 218:930-933.