Dr. Andrea Facciabene’s laboratory is focussed on immunotherapy and investigation of the network of immune responses to tumors, combining basic research and clinical investigation. Our goals are to advance understanding of tumor immunology and to use new findings to develop efficacious new therapies. Our basic research includes the development of two new vaccination strategies: one uses mitochondria isolated from tumors, the other utilizes new tumor vasculature antigen. We also study regulation of immune surveillance and the tumor microenvironment by the gut microbiome. Our clinic research includes the development of new preclinical immunotherapies.