Inclusion / Exclusion Criteria

Inclusion Criteria:

• History of histologically confirmed BE, defined as endoscopically-suspected BE with intestinal metaplasia with globlet cells on esophageal biopsies
• BE length C1M1 of C0M2
• Age 18 years

Exclusion Criteria:

• History of gastric or esophageal surgery
• Inability to give informed consent
• Erosive esophagitis seen on upper endoscopy
• History of prior endoscopic therapy for BE 5 (for controls)
• History of intestinal metaplasia on previous esophageal, GE junction or cardia biopsies