Inclusion / Exclusion Criteria
Eligible cases will be defined as those patients and their family members who meet the following criteria:
Barrett's esophagus confirmed by review of pathology and endoscopy report or adenocarcinoma of the esophagus or family members of person with Barrett's esophagus or adenocarcinoma of the esophagus.
Male or female age 18 or older at time of enrollment or male or female less than 18 years of age at time of enrollment with parental consent. Ability to give informed consent, if patient is age 18 or older.