Geriatric Sleep Research Program

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Title

Role of Melatonin in Secondary Insomnia in the Elderly

Abstract

This study explores the relationship between melatonin abnormalities and insomnia in older adults with co-morbid medical conditions. Melatonin has been linked to the sleep-wake cycle, and plays a role in the circadian regulation of sleep. Older adults have been found, in some studies, to have lower melatonin levels than younger subjects. The presence of co-morbid medical conditions or the use of multiple medications has also been associated with low overall melatonin levels. Our study tests the hypothesize that treatment with melatonin may help improve the sleep quality of older adults with insomnia and co-morbid medical conditions. This study is funded by the National Institute on Aging/National Institutes of Health.

Participating Staff

Nalaka Gooneratne, Principal Investigator
Allan Pack, co-Principal Investigator
Elizabeth Roben, research coordinator
Sumedha Chhatre, biostatistician
Greg Maislin, biostatistician