Mouse Phenotyping, Physiology and Metabolism Core
Translational Research Center
12-213 TRC
Rexford S. Ahima, MD, PhD - Director
To offer expertise and services for determining the metabolic and endocrine phenotpyes of mice with diabetes, obesity and related disorders.
To create a database of physiologic, endocrine and metabolic measurements in mice.
Core Services: SOP Instructions (pdf) | Service request form | New account form | Glucose Clamp form
- Intraperitoneal glucose, insulin and pyuvate tolerance tests
- Insulin clamp and tracer studies
- Comprehensive Laboratory Animal Monitoring System (CLAMS)
- Energy expenditure (Oxymax indirect calorimetry)
- Treadmill exercise and energy expenditure
- Infrared locomotor activity monitoring
- Body composition analysis (DEXA, MRI, and Grip Strength)
- In vivo insulin signaling
- Hyperglycemic clamp
- Cold Tolerance test
- Blood Pressure and Heart Rate
Location:
Diagnostic tests are performed at the Diabetes Research Center (TRC-12-2132, 12-192A, 12-252).
Contact staff at:
Ravindra Dhir, PhD.Technical Director (MPPM Core)
Sr. Research Laboratory Manager
Institute for Diabetes, Obesity, & Metabolism
12-213 TRC
3400 Civic Center Blvd, Building 421
Philadelphia, PA 19104-5160
Email: dhir2@mail.med.upenn.edu
(P) 856-562-9202
(P) 215-573-1873
(F) 215-746-8931
