Mouse Phenotyping, Physiology and Metabolism Core

Translational Research Center
12-213 TRC
Rexford S. Ahima, MD, PhD - Director

Core Aims:

To offer expertise and services for determining the metabolic and endocrine phenotpyes of mice with diabetes, obesity and related disorders.

To create a database of physiologic, endocrine and metabolic measurements in mice.

Core Services: SOP Instructions (pdf) | Service request form | New account form | Glucose Clamp form

  1. Intraperitoneal glucose, insulin and pyuvate tolerance tests
  2. Insulin clamp and tracer studies
  3. Comprehensive Laboratory Animal Monitoring System (CLAMS)
  4. Energy expenditure (Oxymax indirect calorimetry)
  5. Treadmill exercise and energy expenditure
  6. Infrared locomotor activity monitoring
  7. Body composition analysis (DEXA, MRI, and Grip Strength)
  8. In vivo insulin signaling
  9. Hyperglycemic clamp
  10. Cold Tolerance test
  11. Blood Pressure and Heart Rate

Location:

Diagnostic tests are performed at the Diabetes Research Center (TRC-12-2132, 12-192A, 12-252).

Contact staff at:

Ravindra Dhir, PhD.Technical Director (MPPM Core)
Sr. Research Laboratory Manager
Institute for Diabetes, Obesity, & Metabolism
12-213 TRC
3400 Civic Center Blvd, Building 421
Philadelphia, PA 19104-5160

Email: dhir2@mail.med.upenn.edu
(P) 856-562-9202
(P) 215-573-1873
(F) 215-746-8931

Visit the Ahima Lab

© Trustees of the University of Pennsylvania

 

Mouse Phenotyping Core

 

mice

 

Staff

The Ahima Lab

Core Images