Mouse Phenotyping, Physiology and Metabolism Core
Translational Research Center
1-154 SCTR (Smilow Center for Translational Research)
Rexford S. Ahima, MD, PhD - Director
To offer expertise and services for determining the metabolic and endocrine phenotpyes of mice with diabetes, obesity and related disorders.
To create a database of physiologic, endocrine and metabolic measurements in mice.
Core Services: SOP Instructions (pdf) | Service request form | New account form | Glucose Clamp form | Location of Procedures
- Intraperitoneal glucose, insulin and pyuvate tolerance tests
- Insulin clamp and tracer studies
- Comprehensive Laboratory Animal Monitoring System (CLAMS)
- Energy expenditure (Oxymax indirect calorimetry)
- Treadmill exercise and energy expenditure
- Infrared locomotor activity monitoring
- Body composition analysis (DEXA, MRI, and Grip Strength)
- In vivo insulin signaling
- Hyperglycemic clamp
- Cold Tolerance test
- Blood Pressure and Heart Rate
Location:
Diagnostic tests are performed at the Diabetes Research Center SCTR: Smilow Center for Translational Research
Rooms:1-151, 1-152, 1-153, 1-154, 1-154A).
Contact staff at:
Dr. Xiao Y. Yin
Research Specialist C
Institute for Diabetes, Obesity, & Metabolism
1-154 SCTR
3400 Civic Center Blvd, Building 421
Philadelphia, PA 19104-5160
Email: xiaoyy@mail.med.upenn.edu
(Core) 215-573-6331
(P) 856-562-9202
(P) 215-573-1873
(F) 215-746-8931
