Mouse Phenotyping, Physiology and Metabolism Core

Translational Research Center
1-154 SCTR (Smilow Center for Translational Research)
Rexford S. Ahima, MD, PhD - Director

Core Aims:

To offer expertise and services for determining the metabolic and endocrine phenotpyes of mice with diabetes, obesity and related disorders.

To create a database of physiologic, endocrine and metabolic measurements in mice.

Core Services: SOP Instructions (pdf) | Service request form | Chemistry Service Request Form | New account form | Glucose Clamp form | Location of Procedures

  1. Intraperitoneal glucose, insulin and pyuvate tolerance tests
  2. Insulin clamp and tracer studies
  3. Comprehensive Laboratory Animal Monitoring System (CLAMS)
  4. Energy expenditure (Oxymax indirect calorimetry)
  5. Treadmill exercise and energy expenditure
  6. Infrared locomotor activity monitoring
  7. Body composition analysis (DEXA, MRI, and Grip Strength)
  8. In vivo insulin signaling
  9. Hyperglycemic clamp
  10. Cold Tolerance test
  11. Blood Pressure and Heart Rate

Location:

Diagnostic tests are performed at the Diabetes Research Center SCTR: Smilow Center for Translational Research
Rooms:1-151, 1-152, 1-153, 1-154, 1-154A).

Contact staff at:

Frederick Anokye-Danso
Technical Director

Institute for Diabetes, Obesity, & Metabolism SCTR 1-154
3400 Civic Center Blvd, Building 421
Philadelphia, PA 19104-5160

Email: afred@mail.med.upenn.edu
(Core) 215-573-6331
(P): 215-573-1873
(Cell phone): 856-562-9202
(F): 215-746-8931

Dr. Xiao Y. Yin
Research Specialist C
Institute for Diabetes, Obesity, & Metabolism
1-154 SCTR
3400 Civic Center Blvd, Building 421
Philadelphia, PA 19104-5160

Email: xiaoyy@mail.med.upenn.edu
(Core) 215-573-6331
(P) 856-562-9202
(P) 215-573-1873
(F) 215-746-8931

Visit the Ahima Lab

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Mouse Phenotyping Core

 

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Staff

The Ahima Lab

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