Human Metabolism Resource

The Human Metabolism Core aims to assist investigators in the conduct of patient-oriented research specifically relevant to diabetes, obesity and related metabolic disorders. Presently, the core provides support and assistance in the preparation and submission of clinical protocols to the various regulatory bodies.

In addition, the clinical expertise of a diabetes research nurse practitioner is available for assessing insulin sensitivity and secretion by numerous methodologies: including the frequently-sampled intravenous glucose tolerance (FSIGT) test and the hyperinsulinemic euglycemic clamp.  These tests can either be conducted in the Clinical & Translational Research Center or in the Rodebaugh Diabetes Center.

The Human Metabolism Core is under the direction of Drs. Michael Rickels and Karen Teff.

Director:
Michael Rickels, MD, MSc
Phone: 215-746-0025
Email: rickels@mail.med.upenn.edu

Lab Contact:
Cornelia V. Bakes (Ginger)
Phone: 215-746-2085
Email: cornelia.dalton-bakes@uphs.upenn.edu

Investigators should contact Dr. Rickels or Dr. Teff early in the development of their research proposal to aid in study design and ensure selection of the proper methodologies to address metabolic questions in human research.  To utilize the Human Metabolism Core, investigators must be members of IDOM.

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