Today is


8:00 AM Registration and Breakfast (TRC Lobby)
8:30 AM


Welcome and Introduction

J. Larry Jameson, MD, PhD

J. Larry Jameson, MD, PhD
Executive Vice President, University of Pennsylvania for the Health System
Dean, Perelman School of Medicine, University of Pennsylvania

8:40 AM Research at the Intersection of Metabolic and Cardiovascular Disease at Penn

Daniel Rader, MD

Daniel J. Rader, MD
Edward S. Cooper, MD/Norman Roosevelt and Elizabeth Meriwether McLure Professor
Chief, Division of Translational Medicine and Human Genetics

9:00 AM "Epigenomic Modulation of Diabetes and Exercise Tolerance"

Mitch Lazar, MD, PhD

Mitchell A. Lazar, MD, PhD
Sylvan H. Eisman Professor of Medicine
Chief, Division of Endocrinology, Diabetes and Metabolism
Director, Institute for Diabetes, Obesity and Metabolism

9:25 AM “Control of Hepatic Triglyceride Synthesis and Secretion” 

Morrie Birnbaum, MD, PhD

Morris J. Birnbaum, MD, PhD
Willard and Rhoda Ware Professor of Diabetes and Metabolic Diseases

9:50 AM “Mechanisms of the Cardio-Protective Effects of GLP-1”

Richard Shannon, MD

Richard P. Shannon, MD
Frank Wister Thomas Professor of Medicine
Chairman, Department of Medicine

10:15 AM Coffee Break
10:30 AM "Penn CVI and IDOM: Targeting Cardiovascular-Metabolic Diseases"

Michael Parmacek, MD

Michael S. Parmacek, MD
Herbert C. Rorer Professor of Medical Sciences
Chief, Division of Cardiovascular Medicine
Director, Cardiovascular Institute

10:55 AM "Human Genetics of Heart Disease in the context of Diabetes: questions, approaches, and data"

Ben Voight, MD, PhD

Benjamin F. Voight, MD, PhD
Assistant Professor of Pharmacology and Genetics

11:15 AM “Translational models in cardiometabolic disease”

Muredach Reilly, MD

Muredach P. Reilly, MBBCh, MSCE

Associate Professor of Medicine, Cardiovascular Division
Associate Director, Clinical and Translational Research Center (CTRC)

11:40 AM “Regulation of mtDNA abundance and packaging as a determinant for cardiovascular” outcomes

Brett Kaufman, PhD

Brett A. Kaufman, PhD
Assistant Professor of Biochemistry
School of Veterinary Medicine

12:00 Noon “Deciphering the Metabolic Origins of Heart Failure:  A Systems Approach”

Daniel Kelly, MD, PhD

Daniel P. Kelly, MD

Scientific Director, Sanford-Burnham Medical Research Institute-Lake Nona
Professor, Diabetes and Obesity Research Center, Cardiovascular Pathobiology Program

12:55 PM Concluding Remarks - Daniel J. Rader, MD
1:00 PM Lunch