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Agenda

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8:00-8:30 AM  Registration and breakfast
8:30-9:00 AM Opening Remarks by Glen Gaulton, Ph.D.
Executive Vice Dean and Chief Scientific Officer

Remarks by

  • John D. Gearhart, Ph.D
    Director, Institute for Regenerative Medicine
  • Mitchell A. Lazar, M.D., Ph.D.
    Director, Institute for Diabetes, Obesity and Metabolism

Stem Cells and Development.
Moderator: Doris A. Stoffers, M.D., Ph.D.
9:00-9:30 AM Lessons from Development for Beta Cell Programming
Kenneth S. Zaret, Ph.D. (Keynote Lecture)
Professor of Cell and Developmental Biology
Associate Director, Institute for Regenerative Medicine
9:30-10:00 AM The determinants of pancreatic growth
Ben Stanger, M.D., Ph.D.
Assistant Professor of Medicine
10:00-10:15 AM DNase-Chip to Identify Inductive Pathways from Endothelial Cells to Pancreas Progenitors
Deborah Freedman-Cass, Ph.D. *
Sr. Research Investigator, Zaret Lab
10:15-10:45 AM Coffee Break

Postnatal Beta Cell Growth and Function.
Moderator: Klaus Kaestner, Ph.D.
10:45-11:15 AM Proliferation of beta-cells in response to metabolic demand
Klaus Kaestner, Ph.D.
Professor of Genetics
11:15-11:45 AM Cell cycle regulation of islet growth
Jake Kushner, M.D.
Assistant Professor of Pediatrics
11:45-12:15 PM The Role of Islet-1 in the Endocrine Pancreas
Catherine Lee May, Ph.D.
Assistant Professor of Pathology and Laboratory Medicine
12:15-1:45 PM Lunch and Posters

Transition to Translation.
Moderator: Ali Naji, M.D., Ph.D.
1:45-2:00 PM Pcif1 regulates Pdx1 protein stability, glucose homeostasis, and the maintenance of beta cell mass
Kathryn Claiborn *
Graduate Student, Stoffers Lab
2:00-2:15 PM Genetic Analysis of CREB Function in the Pancreas
John Le Lay, Ph.D. *
Postdoctoral Researcher, Kaestner Lab
2:15-2:30 PM The JDRF priorities in Regenerating, Reprogramming and Replacing Beta cell function to treat Type 1 Diabetes
Judy M. Hunt
Chair, Lay Committee, Juvenile Diabetes Research Foundation
2:30 - 3:00 PM Prospects for Beta Cell Preservation in Type 1 Diabetes
Ali Naji, M.D., Ph.D.
Professor of Surgery
3:00-3:30 PM Functional Beta-Cell Mass in Transplantation and Type 2 Diabetes
Michael Rickels, M.D., M.S.
Assistant Professor of Medicine
3:30-4:00 PM  GLP-1 receptor antagonism in congenital hyperinsulinism, pathogenetic
insights and therapeutic potential
Diva D. De León, M.D.
Assistant Professor of Pediatrics
4:00-5:00 PM Reception and Posters
*Chosen among abstract submissions