Penn Institute for Immunology

Perelman School of Medicine at the University of Pennsylvania
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Andras Schaffer

Research Interests: Infectious Diseases, Inflammation

 

Research Description: My main research interest is to better understand the molecular mechanisms underlying myeloid cell-cell fusion and the role of multinucleated syncytia in the pathogenesis of granulomatous inflammation and HIV infection. Specifically, I am exploring how macrophages and dendritic cells achieve fusion competency by identifiyng novel fusion associated molecules that control motility, cell-cell recognition, and membrane fusion.