• Purified human CD8 T-cells

    Erin Zwack/Brodsky Lab & Penn Vet Imaging Core - Murine macrophages infected with Yersinia pseudo tuberculosis. Blue indicates the cell, red is a mitochondrial stain, green is a stain for Yersinia secreted effector proteins.

  • 3D image of the inflamed meningeal membrane of a CX3CR1-GFP reporter mouse

    Claudio Giraudo - Polarization of lytic granules to the immunological synapse during the cytolytic process of human CD8 lymphocytes against cancer cells.

  • Time series of cells expressing GFP-tagged ebola viral protein VP40

    Gretchen Harms, Hunter lab - Stylized images of CD8+ T cells looking at differential localization of the transcription factor T-bet in mouse cells after infection with the parasite Toxoplasma gondii, using the Amnis ImageStream. In the cell in the first and third box, T-bet (red) does not co-localize with DAPI (blue), indicating that it is cytoplas


The IFI Cancer Immunology research program aims to advance the understanding of the immune system's role in neoplastic pathophysiology. Our work spans basic science discoveries, to translational medicine, to clinical care and epidemiology. A major goal is to utilize new insights of immune mechanisms to target malignant cells in relevant in vitro and animal model systems and in human clinical trials.


Cancer Program Highlights

The 3rd Annual Abramson Cancer Center and Institute For Immunlogy Cancer Immunobiology Retreat took place on Thursday, December 21st from 9am-1:15pm in Smilow Rm 10-146 A/B.  The retreat was a resounding success with 19 PI's participating. The purpose of the retreat was to foster greater collaboration and interaction within the cancer immunology community at Penn.


Cancer Retreat 2016