Publications
- Metabolic pathway analysis using stable isotopes in patients with cancer. Bartman CR, Faubert B, Rabinowitz JD, DeBerardinis RJ. Nat Rev Cancer. 2023 Dec;23(12):863-878. doi: 10.1038/s41568-023-00632-z. Epub 2023 Oct 31. PMID: 37907620
- Regulatory T cells control Staphylococcus aureus and disease severity of cutaneous leishmaniasis. Singh TP, Farias Amorim C, Lovins VM, Bradley CW, Carvalho LP, Carvalho EM, Grice EA, Scott P. J Exp Med. 2023 Dec 4;220(12):e20230558. doi: 10.1084/jem.20230558. Epub 2023 Oct 9. PMID: 37812390
- Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion. Sun Y, Florio TJ, Gupta S, Young MC, Marshall QF, Garfinkle SE, Papadaki GF, Truong HV, Mycek E, Li P, Farrel A, Church NL, Jabar S, Beasley MD, Kiefel BR, Yarmarkovich M, Mallik L, Maris JM, Sgourakis NG .Sci Immunol. 2023 Dec;8(90):eadj5792. doi: 10.1126/sciimmunol.adj5792. Epub 2023 Dec 1. PMID: 38039376
- Forks in the road for CAR T and CAR NK cell cancer therapies. Dagher OK, Posey AD Jr. Nat Immunol. 2023 Dec;24(12):1994-2007. doi: 10.1038/s41590-023-01659-y. Epub 2023 Nov 27. PMID: 38012406
- Cold-blooded vertebrates evolved organized germinal center-like structures. Shibasaki Y, Afanasyev S, Fernández-Montero A, Ding Y, Watanabe S, Takizawa F, Lamas J, Fontenla-Iglesias F, Leiro JM, Krasnov A, Boudinot P, Sunyer JO. Sci Immunol. 2023 Dec;8(90):eadf1627. doi: 10.1126/sciimmunol.adf1627. Epub 2023 Dec 1. PMID: 37910630
- The Regulation of Nucleic Acid Vaccine Responses by the Microbiome. Johnson AMF, Hager K, Alameh MG, Van P, Potchen N, Mayer-Blackwell K, Fiore-Gartland A, Minot S, Lin PJC, Tam YK, Weissman D, Kublin JG. J Immunol. 2023 Dec 1;211(11):1680-1692. doi: 10.4049/jimmunol.2300196. PMID: 37850965
- Siglec-7 glyco-immune binding mAbs or NK cell engager biologics induce potent antitumor immunity against ovarian cancers. Bordoloi D, Kulkarni AJ, Adeniji OS, Pampena MB, Bhojnagarwala PS, Zhao S, Ionescu C, Perales-Puchalt A, Parzych EM, Zhu X, Ali AR, Cassel J, Zhang R, Betts MR, Abdel-Mohsen M, Weiner DB. Sci Adv. 2023 Nov 3;9(44):eadh4379. doi: 10.1126/sciadv.adh4379. Epub 2023 Nov 1. PMID: 37910620
- Expression of the transcription factor Klf6 by thymic epithelial cells is required for thymus development. Malin J, Martinez-Ruiz GU, Zhao Y, Shissler SC, Cowan JE, Ding Y, Morales-Sanchez A, Ishikawa M, Lavaert M, Das A, Butcher D, Warner AC, Kallarakal M, Chen J, Kedei N, Kelly M, Brinster LR, Allman D, Bhandoola A. Sci Adv. 2023 Nov 17;9(46):eadg8126. doi: 10.1126/sciadv.adg8126. Epub 2023 Nov 15. PMID: 37967174
- The Proteasome Inhibitor Bortezomib Induces p53-Dependent Apoptosis in Activated B Cells. Ochoa TA, Rossi A, Woodle ES, Hildeman D, Allman D. J Immunol. 2023 Nov 15:ji2300212. doi: 10.4049/jimmunol.2300212. Online ahead of print. PMID: 37966267
- A century of the Warburg effect. Thompson CB, Vousden KH, Johnson RS, Koppenol WH, Sies H, Lu Z, Finley LWS, Frezza C, Kim J, Hu Z, Bartman CR. Nat Metab. 2023 Nov;5(11):1840-1843. doi: 10.1038/s42255-023-00927-3. PMID: 37990075
- Cancer immunotherapy via synergistic coactivation of myeloid receptors CD40 and Dectin-1. Wattenberg MM, Coho H, Herrera VM, Graham K, Stone ML, Xue Y, Chang RB, Cassella C, Liu M, Choi-Bose S, Thomas SK, Choi H, Li Y, Markowitz K, Melendez L, Gianonne M, Bose N, Beatty GL. Sci Immunol. 2023 Nov 17;8(89):eadj5097. doi: 10.1126/sciimmunol.adj5097. Epub 2023 Nov 17. PMID: 37976347
- Proviral location affects cognate peptide-induced virus production and immune recognition of HIV-1-infected T cell clones. Dragoni F, Kwaa AK, Traut CC, Veenhuis RT, Woldemeskel BA, Camilo-Contreras A, Raymond HE, Dykema AG, Scully EP, Rosecrans AM, Smith KN, Bushman FD, Simonetti FR, Blankson JN. J Clin Invest. 2023 Nov 1;133(21):e171097. doi: 10.1172/JCI171097. PMID: 37698927
- Type I interferon signature and cycling lymphocytes in macrophage activation syndrome. Huang Z, Brodeur KE, Chen L, Du Y, Wobma H, Hsu EE, Liu M, Chang JC, Chang MH, Chou J, Day-Lewis M, Dedeoglu F, Halyabar O, Lederer JA, Li T, Lo MS, Lu M, Meidan E, Newburger JW, Randolph AG, Son MB, Sundel RP, Taylor ML, Wu H, Zhou Q, Canna SW, Wei K, Henderson LA, Nigrovic PA, Lee PY. J Clin Invest. 2023 Nov 15;133(22):e165616. doi: 10.1172/JCI165616. PMID: 37751296
- Population-level single-cell genomics reveals conserved gene programs in systemic juvenile idiopathic arthritis. Verweyen EL, Thakkar K, Dhakal S, Baker E, Chetal K, Schnell D, Canna S, Grom AA, Salomonis N, Schulert GS .J Clin Invest. 2023 Nov 15;133(22):e166741. doi: 10.1172/JCI166741. PMID: 37733441
- Checkpoint kinase 2 controls insulin secretion and glucose homeostasis. Chong ACN, Vandana JJ, Jeng G, Li G, Meng Z, Duan X, Zhang T, Qiu Y, Duran-Struuck R, Coker K, Wang W, Li Y, Min Z, Zuo X, de Silva N, Chen Z, Naji A, Hao M, Liu C, Chen S. Nat Chem Biol. 2023 Nov 9. doi: 10.1038/s41589-023-01466-4. Online ahead of print. PMID: 37945898
- c-Myc uses Cul4b to preserve genome integrity and promote antiviral CD8+ T cell immunity. Dar AA, Kim DD, Gordon SM, Klinzing K, Rosen S, Guha I, Porter N, Ortega Y, Forsyth KS, Roof J, Fazelinia H, Spruce LA, Eisenlohr LC, Behrens EM, Oliver PM. Nat Commun. 2023 Nov 4;14(1):7098. doi: 10.1038/s41467-023-42765-7. PMID: 37925424
- Targeting of intracellular oncoproteins with peptide-centric CARs. Yarmarkovich M, Marshall QF, Warrington JM, Premaratne R, Farrel A, Groff D, Li W, di Marco M, Runbeck E, Truong H, Toor JS, Tripathi S, Nguyen S, Shen H, Noel T, Church NL, Weiner A, Kendsersky N, Martinez D, Weisberg R, Christie M, Eisenlohr L, Bosse KR, Dimitrov DS, Stevanovic S, Sgourakis NG, Kiefel BR, Maris JM. Nature. 2023 Nov;623(7988):820-827. doi: 10.1038/s41586-023-06706-0. Epub 2023 Nov 8. PMID: 37938771
- Mapping and modeling human colorectal carcinoma interactions with the tumor microenvironment. Li N, Zhu Q, Tian Y, Ahn KJ, Wang X, Cramer Z, Jou J, Folkert IW, Yu P, Adams-Tzivelekidis S, Sehgal P, Mahmoud NN, Aarons CB, Roses RE, Thomas-Tikhonenko A, Furth EE, Stanger BZ, Rustgi A, Haldar M, Katona BW, Tan K, Lengner CJ. Nat Commun. 2023 Nov 30;14(1):7915. doi: 10.1038/s41467-023-43746-6. PMID: 38036590
- Platelet factor 4 limits neutrophil extracellular trap- and cell-free DNA-induced thrombogenicity and endothelial injury. Ngo AT, Skidmore A, Oberg J, Yarovoi I, Sarkar A, Levine N, Bochenek V, Zhao G, Rauova L, Kowalska MA, Eckart K, Mangalmurti NS, Rux A, Cines DB, Poncz M, Gollomp K. JCI Insight. 2023 Nov 22;8(22):e171054. doi: 10.1172/jci.insight.171054. PMID: 37991024
- Common variable immunodeficiency, cross currents, and prevailing winds. Romberg N, Le Coz C. Immunol Rev. 2023 Nov 28. doi: 10.1111/imr.13291. Online ahead of print. PMID: 38014621
- CAR+ and CAR- T cells share a differentiation trajectory into an NK-like subset after CD19 CAR T cell infusion in patients with B cell malignancies. Louie RHY, Cai C, Samir J, Singh M, Deveson IW, Ferguson JM, Amos TG, McGuire HM, Gowrishankar K, Adikari T, Balderas R, Bonomi M, Ruella M, Bishop D, Gottlieb D, Blyth E, Micklethwaite K, Luciani F. Nat Commun. 2023 Nov 27;14(1):7767. doi: 10.1038/s41467-023-43656-7. PMID: 38012187
- Lineage Plasticity: the New Cancer Hallmark on the Block. Mehta A, Stanger BZ. Cancer Res. 2023 Nov 14. doi: 10.1158/0008-5472.CAN-23-1067. Online ahead of print. PMID: 37963209
- Conditional NKT Cell Depletion in Mice Reveals a Negative Feedback Loop That Regulates CTL Cross-Priming. Heuser-Loy C, Baumgart AK, Hackstein CP, Courrèges CJF, Philipp MS, Thaiss CA, Holland T, Evaristo C, Garbi N, Kurts C. J Immunol. 2023 Nov 29:ji2300662. doi: 10.4049/jimmunol.2300662. Online ahead of print. PMID: 38019126
- A T cell receptor β chain-directed antibody fusion molecule activates and expands subsets of T cells to promote antitumor activity. Hsu J, Donahue RN, Katragadda M, Lowry J, Huang W, Srinivasan K, Guntas G, Tang J, Servattalab R, Moisan J, Tsai YT, Stoop A, Palakurthi S, Chopra R, Liu K, Wherry EJ, Su Z, Gulley JL, Bayliffe A, Schlom J. Sci Transl Med. 2023 Nov 29;15(724):eadi0258. doi: 10.1126/scitranslmed.adi0258. Epub 2023 Nov 29. PMID: 38019931
- A statistical framework for differential pseudotime analysis with multiple single-cell RNA-seq samples. Hou W, Ji Z, Chen Z, Wherry EJ, Hicks SC, Ji H. Nat Commun. 2023 Nov 10;14(1):7286. doi: 10.1038/s41467-023-42841-y. PMID: 37949861
- Estimating the contribution of CD4 T cell subset proliferation and differentiation to HIV persistence. Reeves DB, Bacchus-Souffan C, Fitch M, Abdel-Mohsen M, Hoh R, Ahn H, Stone M, Hecht F, Martin J, Deeks SG, Hellerstein MK, McCune JM, Schiffer JT, Hunt PW. Nat Commun. 2023 Oct 2;14(1):6145. doi: 10.1038/s41467-023-41521-1. PMID: 37783718
- Kupffer cells prevent pancreatic ductal adenocarcinoma metastasis to the liver in mice. Thomas SK, Wattenberg MM, Choi-Bose S, Uhlik M, Harrison B, Coho H, Cassella CR, Stone ML, Patel D, Markowitz K, Delman D, Chisamore M, Drees J, Bose N, Beatty GL. Nat Commun. 2023 Oct 10;14(1):6330. doi: 10.1038/s41467-023-41771-z. PMID: 37816712
- Tracking gut microbiome and bloodstream infection in critically ill adults. Gu CH, Khatib LA, Fitzgerald AS, Graham-Wooten J, Ittner CA, Sherrill-Mix S, Chuang Y, Glaser LJ, Meyer NJ, Bushman FD, Collman RG. PLoS One. 2023 Oct 10;18(10):e0289923. doi: 10.1371/journal.pone.0289923. eCollection 2023. PMID: 37816004
- Proteomics of CKD progression in the chronic renal insufficiency cohort. Dubin RF, Deo R, Ren Y, Wang J, Zheng Z, Shou H, Go AS, Parsa A, Lash JP, Rahman M, Hsu CY, Weir MR, Chen J, Anderson A, Grams ME, Surapaneni A, Coresh J, Li H, Kimmel PL, Vasan RS, Feldman H, Segal MR, Ganz P; CRIC Study Investigators; CKD Biomarkers Consortium. Nat Commun. 2023 Oct 10;14(1):6340. doi: 10.1038/s41467-023-41642-7. PMID: 37816758
- Serotonin reduction in post-acute sequelae of viral infection. Wong AC, Devason AS, Umana IC, Cox TO, Dohnalová L, Litichevskiy L, Perla J, Lundgren P, Etwebi Z, Izzo LT, Kim J, Tetlak M, Descamps HC, Park SL, Wisser S, McKnight AD, Pardy RD, Kim J, Blank N, Patel S, Thum K, Mason S, Beltra JC, Michieletto MF, Ngiow SF, Miller BM, Liou MJ, Madhu B, Dmitrieva-Posocco O, Huber AS, Hewins P, Petucci C, Chu CP, Baraniecki-Zwil G, Giron LB, Baxter AE, Greenplate AR, Kearns C, Montone K, Litzky LA, Feldman M, Henao-Mejia J, Striepen B, Ramage H, Jurado KA, Wellen KE, O'Doherty U, Abdel-Mohsen M, Landay AL, Keshavarzian A, Henrich TJ, Deeks SG, Peluso MJ, Meyer NJ, Wherry EJ, Abramoff BA, Cherry S, Thaiss CA, Levy M. Cell. 2023 Oct 9:S0092-8674(23)01034-6. doi: 10.1016/j.cell.2023.09.013. Online ahead of print. PMID: 37848036
- Trimodal single-cell profiling reveals a novel pediatric CD8αα+ T cell subset and broad age-related molecular reprogramming across the T cell compartment. Thomson Z, He Z, Swanson E, Henderson K, Phalen C, Zaim SR, Pebworth MP, Okada LY, Heubeck AT, Roll CR, Hernandez V, Weiss M, Genge PC, Reading J, Giles JR, Manne S, Dougherty J, Jasen CJ, Greenplate AR, Becker LA, Graybuck LT, Vasaikar SV, Szeto GL, Savage AK, Speake C, Buckner JH, Li XJ, Bumol TF, Wherry EJ, Torgerson TR, Vella LA, Henrickson SE, Skene PJ, Gustafson CE. Nat Immunol. 2023 Oct 16. doi: 10.1038/s41590-023-01641-8. Online ahead of print. PMID: 37845489
- Prior vaccination promotes early activation of memory T cells and enhances immune responses during SARS-CoV-2 breakthrough infection. Painter MM, Johnston TS, Lundgreen KA, Santos JJS, Qin JS, Goel RR, Apostolidis SA, Mathew D, Fulmer B, Williams JC, McKeague ML, Pattekar A, Goode A, Nasta S, Baxter AE, Giles JR, Skelly AN, Felley LE, McLaughlin M, Weaver J; Penn Medicine BioBank; Kuthuru O, Dougherty J, Adamski S, Long S, Kee M, Clendenin C, da Silva Antunes R, Grifoni A, Weiskopf D, Sette A, Huang AC, Rader DJ, Hensley SE, Bates P, Greenplate AR, Wherry EJ. Nat Immunol. 2023 Oct;24(10):1711-1724. doi: 10.1038/s41590-023-01613-y. Epub 2023 Sep 21. PMID: 37735592
- Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells. Tsuchida CA, Brandes N, Bueno R, Trinidad M, Mazumder T, Yu B, Hwang B, Chang C, Liu J, Sun Y, Hopkins CR, Parker KR, Qi Y, Hofman L, Satpathy AT, Stadtmauer EA, Cate JHD, Eyquem J, Fraietta JA, June CH, Chang HY, Ye CJ, Doudna JA. Cell. 2023 Oct 12;186(21):4567-4582.e20. doi: 10.1016/j.cell.2023.08.041. Epub 2023 Oct 3. PMID: 37794590
- Deletion of the inhibitory co-receptor CTLA-4 enhances and invigorates chimeric antigen receptor T cells. Agarwal S, Aznar MA, Rech AJ, Good CR, Kuramitsu S, Da T, Gohil M, Chen L, Hong SA, Ravikumar P, Rennels AK, Salas-Mckee J, Kong W, Ruella M, Davis MM, Plesa G, Fraietta JA, Porter DL, Young RM, June CH. Immunity. 2023 Oct 10;56(10):2388-2407.e9. doi: 10.1016/j.immuni.2023.09.001. Epub 2023 Sep 29. PMID: 37776850
- Garetosmab in fibrodysplasia ossificans progressiva: a randomized, double-blind, placebo-controlled phase 2 trial. Di Rocco M, Forleo-Neto E, Pignolo RJ, Keen R, Orcel P, Funck-Brentano T, Roux C, Kolta S, Madeo A, Bubbear JS, Tabarkiewicz J, Szczepanek M, Bachiller-Corral J, Cheung AM, Dahir KM, Botman E, Raijmakers PG, Mukaddam MA, Tile L, Portal-Celhay C, Sarkar N, Hou P, Musser BJ, Boyapati A, Mohammadi K, Mellis SJ, Rankin AJ, Economides AN, Trotter DG, Herman GA, O'Meara SJ, DelGizzi R, Weinreich DM, Yancopoulos GD, Eekhoff EMW, Kaplan FS. Nat Med. 2023 Oct;29(10):2615-2624. doi: 10.1038/s41591-023-02561-8. Epub 2023 Sep 28. PMID: 37770652
- SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC). Proal AD, VanElzakker MB, Aleman S, Bach K, Boribong BP, Buggert M, Cherry S, Chertow DS, Davies HE, Dupont CL, Deeks SG, Eimer W, Ely EW, Fasano A, Freire M, Geng LN, Griffin DE, Henrich TJ, Iwasaki A, Izquierdo-Garcia D, Locci M, Mehandru S, Painter MM, Peluso MJ, Pretorius E, Price DA, Putrino D, Scheuermann RH, Tan GS, Tanzi RE, VanBrocklin HF, Yonker LM, Wherry EJ. Nat Immunol. 2023 Oct;24(10):1616-1627. doi: 10.1038/s41590-023-01601-2. Epub 2023 Sep 4. PMID: 37667052
- Cryptic MHC-E epitope from influenza elicits a potent cytolytic T cell response. Hogan MJ, Maheshwari N, Begg BE, Nicastri A, Hedgepeth EJ, Muramatsu H, Pardi N, Miller MA, Reilly SP, Brossay L, Lynch KW, Ternette N, Eisenlohr LC. Nat Immunol. 2023 Oct 12. doi: 10.1038/s41590-023-01644-5. Online ahead of print. PMID: 37828378
- CD8+ T cells in the cancer-immunity cycle. Giles JR, Globig AM, Kaech SM, Wherry EJ. Immunity. 2023 Oct 10;56(10):2231-2253. doi: 10.1016/j.immuni.2023.09.005. PMID: 37820583
- NfL is ready for translation into paediatrics. Thebault S, Bar-Or A, Banwell B. Lancet Neurol. 2023 Sep;22(9):774-776. doi: 10.1016/S1474-4422(23)00284-3. Epub 2023 Jul 28. PMID: 37524099
- Multiomic profiling of cutaneous leishmaniasis infections reveals microbiota-driven mechanisms underlying disease severity. Farias Amorim C, Lovins VM, Singh TP, Novais FO, Harris JC, Lago AS, Carvalho LP, Carvalho EM, Beiting DP, Scott P, Grice EA. Sci Transl Med. 2023 Oct 18;15(718):eadh1469. doi: 10.1126/scitranslmed.adh1469. Epub 2023 Oct 18.PMID: 37851822
- Unedited allogeneic iNKT cells show extended persistence in MHC-mismatched canine recipients. Rotolo A, Whelan EC, Atherton MJ, Kulikovskaya I, Jarocha D, Fraietta JA, Kim MM, Diffenderfer ES, Cengel KA, Piviani M, Radaelli E, Duran-Struuck R, Mason NJ. Cell Rep Med. 2023 Oct 17;4(10):101241. doi: 10.1016/j.xcrm.2023.101241. PMID: 37852175
- Variable staphyloxanthin production by Staphylococcus aureus drives strain-dependent effects on diabetic wound-healing outcomes. Campbell AE, McCready-Vangi AR, Uberoi A, Murga-Garrido SM, Lovins VM, White EK, Pan JT, Knight SAB, Morgenstern AR, Bianco C, Planet PJ, Gardner SE, Grice EA. Cell Rep. 2023 Oct 31;42(10):113281. doi: 10.1016/j.celrep.2023.113281. Epub 2023 Oct 19. PMID: 37858460
- Short chain fatty acids facilitate protective immunity by macrophages and T cells during acute fowl adenovirus-4 infection. Lee R, Yoon BI, Hunter CA, Kwon HM, Sung HW, Park J. Sci Rep. 2023 Oct 21;13(1):17999. doi: 10.1038/s41598-023-45340-8. PMID: 37865711
- Diacylglycerol kinase zeta deficiency attenuates papain-induced type 2 airway inflammation. Singh BK, Yokoyama Y, Tanaka Y, Laczkó D, Deshpande DA, Kambayashi T. Cell Immunol. 2023 Oct 30;393-394:104780. doi: 10.1016/j.cellimm.2023.104780. Online ahead of print. PMID: 37918056
- Ventral striatal islands of Calleja neurons bidirectionally mediate depression-like behaviors in mice. Zhang YF, Wu J, Wang Y, Johnson NL, Bhattarai JP, Li G, Wang W, Guevara C, Shoenhard H, Fuccillo MV, Wesson DW, Ma M. Nat Commun. 2023 Oct 28;14(1):6887. doi: 10.1038/s41467-023-42662-z. PMID: 37898623
- Intestinal transit amplifying cells require METTL3 for growth factor signaling and cell survival. Danan CH, Naughton KE, Hayer KE, Vellappan S, McMillan EA, Zhou Y, Matsuda R, Nettleford SK, Katada K, Parham LR, Ma X, Chowdhury A, Wilkins BJ, Shah P, Weitzman MD, Hamilton KE. JCI Insight. 2023 Oct 26:e171657. doi: 10.1172/jci.insight.171657. Online ahead of print. PMID: 37883185
- Author Correction: Human circulating and tissue-resident memory CD8+ T cells. Buggert M, Price DA, Mackay LK, Betts MR. Nat Immunol. 2023 Sep;24(9):1591. doi: 10.1038/s41590-023-01586-y. PMID: 37460642
- Myo-differentiation reporter screen reveals NF-Y as an activator of PAX3-FOXO1 in rhabdomyosarcoma. Sroka MW, Skopelitis D, Vermunt MW, Preall JB, El Demerdash O, de Almeida LMN, Chang K, Utama R, Gryder B, Caligiuri G, Ren D, Nalbant B, Milazzo JP, Tuveson DA, Dobin A, Hiebert SW, Stengel KR, Mantovani R, Khan J, Kohli RM, Shi J, Blobel GA, Vakoc CR. Proc Natl Acad Sci U S A. 2023 Sep 5;120(36):e2303859120. doi: 10.1073/pnas.2303859120. Epub 2023 Aug 28.PMID: 37639593
- Innate immune memory, trained immunity and nomenclature clarification. Hajishengallis G, Netea MG, Chavakis T. Nat Immunol. 2023 Sep;24(9):1393-1394. doi: 10.1038/s41590-023-01595-x. PMID: 37620602
- PD-L1 positive astrocytes attenuate inflammatory functions of PD-1 positive microglia in models of autoimmune neuroinflammation. Linnerbauer M, Beyer T, Nirschl L, Farrenkopf D, Lößlein L, Vandrey O, Peter A, Tsaktanis T, Kebir H, Laplaud D, Oellinger R, Engleitner T, Alvarez JI, Rad R, Korn T, Hemmer B, Quintana FJ, Rothhammer V. Nat Commun. 2023 Sep 9;14(1):5555. doi: 10.1038/s41467-023-40982-8. PMID: 37689786
- Human OPRM1 and murine Oprm1 promoter driven viral constructs for genetic access to μ-opioidergic cell types. Salimando GJ, Tremblay S, Kimmey BA, Li J, Rogers SA, Wojick JA, McCall NM, Wooldridge LM, Rodrigues A, Borner T, Gardiner KL, Jayakar SS, Singeç I, Woolf CJ, Hayes MR, De Jonghe BC, Bennett FC, Bennett ML, Blendy JA, Platt ML, Creasy KT, Renthal WR, Ramakrishnan C, Deisseroth K, Corder G. Nat Commun. 2023 Sep 13;14(1):5632. doi: 10.1038/s41467-023-41407-2. PMID: 37704594
- Proviral location affects cognate peptide-induced virus production and immune recognition of HIV-1-infected T cell clones. Dragoni F, Kwaa A, Traut CC, Veenhuis RT, Woldemeskel BA, Camilo-Contreras A, Raymond HE, Dykema AG, Scully EP, Rosecrans AM, Smith KN, Bushman FD, Simonetti FR, Blankson JN. J Clin Invest. 2023 Sep 12:e171097. doi: 10.1172/JCI171097. Online ahead of print. PMID: 37698927
- Type I interferon signature and cycling lymphocytes in macrophage activation syndrome. Huang Z, Brodeur KE, Chen L, Du Y, Wobma H, Hsu EE, Liu M, Chang JC, Chang MH, Chou J, Day-Lewis M, Dedeoglu F, Halyabar O, Lederer JA, Li T, Lo MS, Lu M, Meidan E, Newburger JW, Randolph AG, Son MBF, Sundel RP, Taylor ML, Wu H, Zhou Q, Canna SW, Wei K, Henderson LA, Nigrovic PA, Lee PY. J Clin Invest. 2023 Sep 26:e165616. doi: 10.1172/JCI165616. Online ahead of print. PMID: 37751296
- Population-level single-cell genomics reveals conserved gene programs in systemic juvenile idiopathic arthritis. Verweyen EL, Thakkar K, Dhakal S, Baker EJ, Chetal K, Schnell D, Canna SW, Grom AA, Salomonis N, Schulert GS. J Clin Invest. 2023 Sep 21:e166741. doi: 10.1172/JCI166741. Online ahead of print. PMID: 37733441
- Iron oxide nanozymes stabilize stannous fluoride for targeted biofilm killing and synergistic oral disease prevention. Huang Y, Liu Y, Pandey NK, Shah S, Simon-Soro A, Hsu JC, Ren Z, Xiang Z, Kim D, Ito T, Oh MJ, Buckley C, Alawi F, Li Y, Smeets PJM, Boyer S, Zhao X, Joester D, Zero DT, Cormode DP, Koo H. Nat Commun. 2023 Sep 29;14(1):6087. doi: 10.1038/s41467-023-41687-8. PMID: 37773239
- Precision targeting of autoantigen-specific B cells in muscle-specific tyrosine kinase myasthenia gravis with chimeric autoantibody receptor T cells. Oh S, Mao X, Manfredo-Vieira S, Lee J, Patel D, Choi EJ, Alvarado A, Cottman-Thomas E, Maseda D, Tsao PY, Ellebrecht CT, Khella SL, Richman DP, O'Connor KC, Herzberg U, Binder GK, Milone MC, Basu S, Payne AS. Nat Biotechnol. 2023 Sep;41(9):1229-1238. doi: 10.1038/s41587-022-01637-z. Epub 2023 Jan 19 .PMID: 36658341
- Epitope base editing CD45 in hematopoietic cells enables universal blood cancer immune therapy. Wellhausen N, O'Connell RP, Lesch S, Engel NW, Rennels AK, Gonzales D, Herbst F, Young RM, Garcia KC, Weiner D, June CH, Gill SI. Sci Transl Med. 2023 Sep 20;15(714):eadi1145. doi: 10.1126/scitranslmed.adi1145. Epub 2023 Sep 20. PMID: 37651540
- A guide to complement biology, pathology and therapeutic opportunity. Mastellos DC, Hajishengallis G, Lambris JD. Nat Rev Immunol. 2023 Sep 5. doi: 10.1038/s41577-023-00926-1. Online ahead of print. PMID: 37670180
- Innate immune memory, trained immunity and nomenclature clarification. Hajishengallis G, Netea MG, Chavakis T. Nat Immunol. 2023 Sep;24(9):1393-1394. doi: 10.1038/s41590-023-01595-x. PMID: 37620602
- Breakthroughs in understanding and treating eosinophilic gastrointestinal diseases presented at the CEGIR/TIGERs Symposium at the 2022 American Academy of Allergy, Asthma & Immunology Meeting. Chehade M, Wright BL, Atkins D, Aceves SS, Ackerman SJ, Assa'ad AH, Bauer M, Collins MH, Commins SP, Davis CM, Dellon ES, Doerfler B, Gleich GJ, Gupta SK, Hill DA, Jensen ET, Katzka D, Kliewer K, Kodroff E, Kottyan LC, Kyle S, Muir AB, Pesek RD, Peterson K, Shreffler WG, Spergel JM, Strobel MJ, Wechsler J, Zimmermann N, Furuta GT, Rothenberg ME. J Allergy Clin Immunol. 2023 Sep 3:S0091-6749(23)01103-X. doi: 10.1016/j.jaci.2023.08.021. Online ahead of print. PMID: 37660987
- Immunity to Cryptosporidium: insights into principles of enteric responses to infection. Pardy RD, Wallbank BA, Striepen B, Hunter CA. Nat Rev Immunol. 2023 Sep 11. doi: 10.1038/s41577-023-00932-3. Online ahead of print. PMID: 37697084
- A phase 1 trial of adoptive transfer of vaccine-primed autologous circulating T cells in ovarian cancer. Bobisse S, Bianchi V, Tanyi JL, Sarivalasis A, Missiaglia E, Pétremand R, Benedetti F, Torigian DA, Genolet R, Barras D, Michel A, Mastroyannis SA, Zsiros E, Dangaj Laniti D, Tsourti Z, Stevenson BJ, Iseli C, Levine BL, Speiser DE, Gfeller D, Bassani-Sternberg M, Powell DJ Jr, June CH, Dafni U, Kandalaft LE, Harari A, Coukos G. Nat Cancer. 2023 Sep 21. doi: 10.1038/s43018-023-00623-x. Online ahead of print. PMID: 37735588
- Induced Abortion and the Risk of Rh Sensitization. Horvath S, Huang ZY, Koelper NC, Martinez C, Tsao PY, Zhao L, Goldberg AB, Hannum C, Putt ME, Luning Prak ET, Schreiber CA. JAMA. 2023 Sep 26;330(12):1167-1174. doi: 10.1001/jama.2023.16953. PMID: 37750879
- Preclinical development of a chimeric antigen receptor T cell therapy targeting FGFR4 in rhabdomyosarcoma. Tian M, Wei JS, Shivaprasad N, Highfill SL, Gryder BE, Milewski D, Brown GT, Moses L, Song H, Wu JT, Azorsa P, Kumar J, Schneider D, Chou HC, Song YK, Rahmy A, Masih KE, Kim YY, Belyea B, Linardic CM, Dropulic B, Sullivan PM, Sorensen PH, Dimitrov DS, Maris JM, Mackall CL, Orentas RJ, Cheuk AT, Khan J. Cell Rep Med. 2023 Sep 21:101212. doi: 10.1016/j.xcrm.2023.101212. Online ahead of print. PMID: 37774704
- Enterobacter cloacae, a Rare Cause of Cervical Lymphadenitis in X-Linked Chronic Granulomatous Disease. Penner C, Datta R, Ebube J, Romberg N. J Clin Immunol. 2023 Sep 28. doi: 10.1007/s10875-023-01586-5. Online ahead of print. PMID: 37768436
- Plant cell-based drug delivery enhances affordability of biologics. Daniell H, Kulchar RJ, Herzog RW, Kulis M, Leong KW. Nat Biotechnol. 2023 Sep;41(9):1186-1187. doi: 10.1038/s41587-023-01899-1. PMID: 37550435
- The Lancet Commission to reduce the global burden of sudden cardiac death: a call for multidisciplinary action. Marijon E, Narayanan K, Smith K, Barra S, Basso C, Blom MT, Crotti L, D'Avila A, Deo R, Dumas F, Dzudie A, Farrugia A, Greeley K, Hindricks G, Hua W, Ingles J, Iwami T, Junttila J, Koster RW, Le Polain De Waroux JB, Olasveengen TM, Ong MEH, Papadakis M, Sasson C, Shin SD, Tse HF, Tseng Z, Van Der Werf C, Folke F, Albert CM, Winkel BG. Lancet. 2023 Sep 9;402(10405):883-936. doi: 10.1016/S0140-6736(23)00875-9. Epub 2023 Aug 27. PMID: 37647926
- Cooperative phagocytosis of solid tumours by macrophages triggers durable anti-tumour responses. Dooling LJ, Andrechak JC, Hayes BH, Kadu S, Zhang W, Pan R, Vashisth M, Irianto J, Alvey CM, Ma L, Discher DE. Nat Biomed Eng. 2023 Sep;7(9):1081-1096. doi: 10.1038/s41551-023-01031-3. Epub 2023 Apr 24. PMID: 37095318
- Suppression of protein quality control system by TRIM30a sensitises tumour cells to NK cell-mediated immune surveillance. Afolabi LO, Bi J, Chen L, Yang X, Wan X. Immunology. 2023 Sep 27. doi: 10.1111/imm.13694. Online ahead of print. PMID: 37753964
- In vitro modeling of CD8+ T cell exhaustion enables CRISPR screening to reveal a role for BHLHE40. Wu JE, Manne S, Ngiow SF, Baxter AE, Huang H, Freilich E, Clark ML, Lee JH, Chen Z, Khan O, Staupe RP, Huang YJ, Shi J, Giles JR, Wherry EJ. Sci Immunol. 2023 Aug 25;8(86):eade3369. doi: 10.1126/sciimmunol.ade3369. Epub 2023 Aug 18. PMID: 37595022
- Throughput-scalable manufacturing of SARS-CoV-2 mRNA lipid nanoparticle vaccines. Shepherd SJ, Han X, Mukalel AJ, El-Mayta R, Thatte AS, Wu J, Padilla MS, Alameh MG, Srikumar N, Lee D, Weissman D, Issadore D, Mitchell MJ. Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e2303567120. doi: 10.1073/pnas.2303567120. Epub 2023 Aug 9. PMID: 37556502
- Intrinsically disordered domain of transcription factor TCF-1 is required for T cell developmental fidelity. Goldman N, Chandra A, Johnson I, Sullivan MA, Patil AR, Vanderbeck A, Jay A, Zhou Y, Ferrari EK, Mayne L, Aguilan J, Xue HH, Faryabi RB, John Wherry E, Sidoli S, Maillard I, Vahedi G. Nat Immunol. 2023 Aug 17. doi: 10.1038/s41590-023-01599-7. Online ahead of print. PMID: 37592014
- Modeling and optimization of parallelized immunomagnetic nanopore sorting for surface marker specific isolation of extracellular vesicles from complex media. Lin AA, Shen H, Spychalski G, Carpenter EL, Issadore D. Sci Rep. 2023 Aug 16;13(1):13292. doi: 10.1038/s41598-023-39746-7. PMID: 37587235
- Management of Primary Immune Thrombocytopenia in Pregnancy. Bussel JB, Hou M, Cines DB. N Engl J Med. 2023 Aug 10;389(6):540-548. doi: 10.1056/NEJMra2214617. PMID: 37590449
- Plant cell-based drug delivery enhances affordability of biologics. Daniell H, Kulchar RJ, Herzog RW, Kulis M, Leong KW. Nat Biotechnol. 2023 Aug 7. doi: 10.1038/s41587-023-01899-1. Online ahead of print. PMID: 37550435
- The Lancet Commission to reduce the global burden of sudden cardiac death: a call for multidisciplinary action. Marijon E, Narayanan K, Smith K, Barra S, Basso C, Blom MT, Crotti L, D'Avila A, Deo R, Dumas F, Dzudie A, Farrugia A, Greeley K, Hindricks G, Hua W, Ingles J, Iwami T, Junttila J, Koster RW, Le Polain De Waroux JB, Olasveengen TM, Ong MEH, Papadakis M, Sasson C, Shin SD, Tse HF, Tseng Z, Van Der Werf C, Folke F, Albert CM, Winkel BG. Lancet. 2023 Aug 24:S0140-6736(23)00875-9. doi: 10.1016/S0140-6736(23)00875-9. Online ahead of print. PMID: 37647926
- IgG3 subclass antibodies recognize antigenically drifted influenza viruses and SARS-CoV-2 variants through efficient bivalent binding. Bolton MJ, Santos JJS, Arevalo CP, Griesman T, Watson M, Li SH, Bates P, Ramage H, Wilson PC, Hensley SE. Proc Natl Acad Sci U S A. 2023 Aug 29;120(35):e2216521120. doi: 10.1073/pnas.2216521120. Epub 2023 Aug 21. PMID: 37603748
- Author Correction: A positive feedback loop controls Toxoplasma chronic differentiation. Licon MH, Giuliano CJ, Chan AW, Chakladar S, Eberhard JN, Shallberg LA, Chandrasekaran S, Waldman BS, Koshy AA, Hunter CA, Lourido S. Nat Microbiol. 2023 Aug 15. doi: 10.1038/s41564-023-01467-y. Online ahead of print. PMID: 37582867
- Desmoplastic stroma restricts T cell extravasation and mediates immune exclusion and immunosuppression in solid tumors. Xiao Z, Todd L, Huang L, Noguera-Ortega E, Lu Z, Huang L, Kopp M, Li Y, Pattada N, Zhong W, Guo W, Scholler J, Liousia M, Assenmacher CA, June CH, Albelda SM, Puré E. Nat Commun. 2023 Aug 22;14(1):5110. doi: 10.1038/s41467-023-40850-5. PMID: 37607999
- Structural basis for high-order complex of SARNP and DDX39B to facilitate mRNP assembly. Xie Y, Gao S, Zhang K, Bhat P, Clarke BP, Batten K, Mei M, Gazzara M, Shay JW, Lynch KW, Angelos AE, Hill PS, Ivey AL, Fontoura B, Ren Y. Cell Rep. 2023 Aug 12;42(8):112988. doi: 10.1016/j.celrep.2023.112988. Online ahead of print. PMID: 37578863
- Having it both ways: how STAT3 deficiency blocks graft-versus-host disease while preserving graft-versus-leukemia activity. Brandstadter JD, Outen R, Maillard I .J Clin Invest. 2023 Aug 1;133(15):e172251. doi: 10.1172/JCI172251. PMID: 37526083
- Polyclonal lymphoid expansion drives paraneoplastic autoimmunity in neuroblastoma. Rosenberg MI, Greenstein E, Buchkovich M, Peres A, Santoni-Rugiu E, Yang L, Mikl M, Vaksman Z, Gibbs DL, Reshef D, Salovin A, Irwin MS, Naranjo A, Ulitsky I, de Alarcon PA, Matthay KK, Weigman V, Yaari G, Panzer JA, Friedman N, Maris JM. Cell Rep. 2023 Aug 1;42(8):112879. doi: 10.1016/j.celrep.2023.112879. Online ahead of print. PMID: 37537844
- Uptake of Genetic Research Results and Patient-Reported Outcomes With Return of Results Incorporating Web-Based Predisclosure Education. Kilbride M, Egleston BL, Chung WK, Olopade O, Maxwell KN, Shah P, Churpek JE, Fleisher L, Terry MB, Fetzer D, Gaieski JB, Bulafka J, Espinal A, Karpink K, Walser S, Singleton D, Palese M, Siljander I, Brandt A, Clark D, Koval C, Wynn J, Long JM, McKenna D, Powers J, Nielsen S, Domchek SM, Nathanson KL, Bradbury AR. J Clin Oncol. 2023 Aug 23:JCO2200516. doi: 10.1200/JCO.22.00516. Online ahead of print. PMID: 37611220
- Intradermal but not intramuscular modified vaccinia Ankara immunizations protect against intravaginal tier2 simian-human immunodeficiency virus challenges in female macaques. Bollimpelli VS, Reddy PBJ, Gangadhara S, Charles TP, Burton SL, Tharp GK, Styles TM, Labranche CC, Smith JC, Upadhyay AA, Sahoo A, Legere T, Shiferaw A, Velu V, Yu T, Tomai M, Vasilakos J, Kasturi SP, Shaw GM, Montefiori D, Bosinger SE, Kozlowski PA, Pulendran B, Derdeyn CA, Hunter E, Amara RR. Nat Commun. 2023 Aug 8;14(1):4789. doi: 10.1038/s41467-023-40430-7. PMID: 37553348
- Origin and arrangement of actin filaments for gliding motility in apicomplexan parasites revealed by cryo-electron tomography. Martinez M, Mageswaran SK, Guérin A, Chen WD, Thompson CP, Chavin S, Soldati-Favre D, Striepen B, Chang YW. Nat Commun. 2023 Aug 9;14(1):4800. doi: 10.1038/s41467-023-40520-6. PMID: 37558667
- Swiss army knife T cell: one T cell many tumor targets. Berjis A, Muthumani D, Sheppard NC, June CH. Cell Res. 2023 Sep 4. doi: 10.1038/s41422-023-00871-7. Online ahead of print. PMID: 37666977
- Theranostic gold-in-gold cage nanoparticles enable photothermal ablation and photoacoustic imaging in biofilm-associated infection models. Hajfathalian M, de Vries CR, Hsu JC, Amirshaghaghi A, Dong YC, Ren Z, Liu Y, Huang Y, Li Y, Knight SA, Jonnalagadda P, Zlitni A, Grice EA, Bollyky PL, Koo H, Cormode DP. J Clin Invest. 2023 Aug 31:e168485. doi: 10.1172/JCI168485. Online ahead of print. PMID: 37651187
- Induction of bronchus-associated lymphoid tissue is an early life adaptation for promoting human B cell immunity. Matsumoto R, Gray J, Rybkina K, Oppenheimer H, Levy L, Friedman LM, Khamaisi M, Meng W, Rosenfeld AM, Guyer RS, Bradley MC, Chen D, Atkinson MA, Brusko TM, Brusko M, Connors TJ, Luning Prak ET, Hershberg U, Sims PA, Hertz T, Farber DL. Nat Immunol. 2023 Aug;24(8):1370-1381. doi: 10.1038/s41590-023-01557-3. Epub 2023 Jul 17. PMID: 37460638
- The pseudokinase Trib1 regulates the transition of exhausted T cells to a KLR+CD8+ effector state, and its deletion improves checkpoint blockade. McClory SE, Bardhan O, Rome KS, Giles JR, Baxter AE, Xu L, Gimotty PA, Faryabi RB, Wherry EJ, Pear WS, Jordan MS. Cell Rep. 2023 Aug 29;42(8):112905. doi: 10.1016/j.celrep.2023.112905. Epub 2023 Jul 31. PMID: 37527035
- Circadian regulation of lung repair and regeneration. Naik A, Forrest KM, Paul O, Issah Y, Valekunja UK, Tang SY, Reddy AB, Hennessy EJ, Brooks TG, Chaudhry F, Babu A, Morley M, Zepp JA, Grant GR, FitzGerald GA, Sehgal A, Worthen GS, Frank DB, Morrisey EE, Sengupta S. JCI Insight. 2023 Aug 22;8(16):e164720. doi: 10.1172/jci.insight.164720. PMID: 37463053
- Human circulating and tissue-resident memory CD8+ T cells. Buggert M, Price DA, Mackay LK, Betts MR. Nat Immunol. 2023 Jul;24(7):1076-1086. doi: 10.1038/s41590-023-01538-6. Epub 2023 Jun 22. PMID: 37349380 Review.
- The pseudokinase Trib1 regulates the transition of exhausted T cells to a KLR+CD8+ effector state, and its deletion improves checkpoint blockade. McClory SE, Bardhan O, Rome KS, Giles JR, Baxter AE, Xu L, Gimotty PA, Faryabi RB, Wherry EJ, Pear WS, Jordan MS. Cell Rep. 2023 Jul 31;42(8):112905. doi: 10.1016/j.celrep.2023.112905. Online ahead of print. PMID: 37527035
-
Author Correction: A viral biomolecular condensate coordinates assembly of progeny particles. Charman M, Grams N, Kumar N, Halko E, Dybas JM, Abbott A, Lum KK, Blumenthal D, Tsopurashvili E, Weitzman MD. Nature. 2023 Jul;619(7969):E38. doi: 10.1038/s41586-023-06343-7. PMID: 37353705
-
In vivo hematopoietic stem cell modification by mRNA delivery. Breda L, Papp TE, Triebwasser MP, Yadegari A, Fedorky MT, Tanaka N, Abdulmalik O, Pavani G, Wang Y, Grupp SA, Chou ST, Ni H, Mui BL, Tam YK, Weissman D, Rivella S, Parhiz H. Science. 2023 Jul 28;381(6656):436-443. doi: 10.1126/science.ade6967. Epub 2023 Jul 27. PMID: 37499029
-
The latent reservoir of inducible, infectious HIV-1 does not decrease despite decades of antiretroviral therapy. McMyn NF, Varriale J, Fray EJ, Zitzmann C, MacLeod HJ, Lai J, Singhal A, Moskovljevic M, Garcia MA, Lopez BM, Hariharan V, Rhodehouse K, Lynn K, Tebas P, Mounzer K, Montaner LJ, Benko E, Kovacs C, Hoh R, Simonetti FR, Laird GM, Deeks SG, Ribeiro RM, Perelson AS, Siliciano R, Siliciano JM. J Clin Invest. 2023 Jul 18:e171554. doi: 10.1172/JCI171554. Online ahead of print. PMID: 37463049
-
Measuring the effect of newborn screening on survival after haematopoietic cell transplantation for severe combined immunodeficiency: a 36-year longitudinal study from the Primary Immune Deficiency Treatment Consortium. Thakar MS, Logan BR, Puck JM, Dunn EA, Buckley RH, Cowan MJ, O'Reilly RJ, Kapoor N, Satter LF, Pai SY, Heimall J, Chandra S, Ebens CL, Chellapandian D, Williams O, Burroughs LM, Saldana BD, Rayes A, Madden LM, Chandrakasan S, Bednarski JJ 2nd, DeSantes KB, Cuvelier GDE, Teira P, Gillio AP, Eissa H, Knutsen AP, Goldman FD, Aquino VM, Shereck EB, Moore TB, Caywood EH, Lugt MTV, Rozmus J, Broglie L, Yu LC, Shah AJ, Andolina JR, Liu X, Parrott RE, Dara J, Prockop S, Martinez CA, Kapadia M, Jyonouchi SC, Sullivan KE, Bleesing JJ, Chaudhury S, Petrovic A, Keller MD, Quigg TC, Parikh S, Shenoy S, Seroogy C, Rubin T, Decaluwe H, Routes JM, Torgerson TR, Leiding JW, Pulsipher MA, Kohn DB, Griffith LM, Haddad E, Dvorak CC, Notarangelo LD. Lancet. 2023 Jul 8;402(10396):129-140. doi: 10.1016/S0140-6736(23)00731-6. Epub 2023 Jun 20. PMID: 37352885
-
p53 restoration in small cell lung cancer identifies a latent cyclophilin-dependent necrosis mechanism. Acosta J, Li Q, Freeburg NF, Murali N, Indeglia A, Grothusen GP, Cicchini M, Mai H, Gladstein AC, Adler KM, Doerig KR, Li J, Ruiz-Torres M, Manning KL, Stanger BZ, Busino L, Murphy M, Wan L, Feldser DM. Nat Commun. 2023 Jul 21;14(1):4403. doi: 10.1038/s41467-023-40161-9. PMID: 37479684 PMCID: PMC10362054
-
Genome-wide association study of thoracic aortic aneurysm and dissection in the Million Veteran Program. Klarin D, Devineni P, Sendamarai AK, Angueira AR, Graham SE, Shen YH, Levin MG, Pirruccello JP, Surakka I, Karnam PR, Roychowdhury T, Li Y, Wang M, Aragam KG, Paruchuri K, Zuber V, Shakt GE, Tsao NL, Judy RL, Vy HMT, Verma SS, Rader DJ, Do R, Bavaria JE, Nadkarni GN, Ritchie MD; VA Million Veteran Program; Burgess S, Guo DC, Ellinor PT, LeMaire SA, Milewicz DM, Willer CJ, Natarajan P, Tsao PS, Pyarajan S, Damrauer SM. Nat Genet. 2023 Jul;55(7):1106-1115. doi: 10.1038/s41588-023-01420-z. Epub 2023 Jun 12. PMID: 37308786
-
The latent reservoir of inducible, infectious HIV-1 does not decrease despite decades of antiretroviral therapy. McMyn NF, Varriale J, Fray EJ, Zitzmann C, MacLeod HJ, Lai J, Singhal A, Moskovljevic M, Garcia MA, Lopez BM, Hariharan V, Rhodehouse K, Lynn K, Tebas P, Mounzer K, Montaner LJ, Benko E, Kovacs C, Hoh R, Simonetti FR, Laird GM, Deeks SG, Ribeiro RM, Perelson AS, Siliciano R, Siliciano JM .J Clin Invest. 2023 Jul 18:e171554. doi: 10.1172/JCI171554. Online ahead of print. PMID: 37463049
-
Pediatric phase 2 trial of a WEE1 inhibitor, adavosertib (AZD1775), and irinotecan for relapsed neuroblastoma, medulloblastoma, and rhabdomyosarcoma. Cole KA, Ijaz H, Surrey LF, Santi M, Liu X, Minard CG, Maris JM, Voss S, Reid JM, Fox E, Weigel BJ. Cancer. 2023 Jul 15;129(14):2245-2255. doi: 10.1002/cncr.34786. Epub 2023 Apr 20. PMID: 37081608
-
PI16+ reticular cells in human palatine tonsils govern T cell activity in distinct subepithelial niches. De Martin A, Stanossek Y, Lütge M, Cadosch N, Onder L, Cheng HW, Brandstadter JD, Maillard I, Stoeckli SJ, Pikor NB, Ludewig B. Nat Immunol. 2023 Jul;24(7):1138-1148. doi: 10.1038/s41590-023-01502-4. Epub 2023 May 18. PMID: 37202490 PMCID: PMC10307632
-
VEGFR3 is required for button junction formation in lymphatic vessels. Jannaway M, Iyer D, Mastrogiacomo DM, Li K, Sung DC, Yang Y, Kahn ML, Scallan JP. Cell Rep. 2023 Jul 25;42(7):112777. doi: 10.1016/j.celrep.2023.112777. Epub 2023 Jul 16. PMID: 37454290
-
CAR T therapy beyond cancer: the evolution of a living drug. Baker DJ, Arany Z, Baur JA, Epstein JA, June CH. Nature. 2023 Jul;619(7971):707-715. doi: 10.1038/s41586-023-06243-w. Epub 2023 Jul 26. PMID: 37495877
-
CXCL9 inhibition does not ameliorate disease in murine models of both primary and secondary hemophagocytic lymphohistiocytosis. Diamond T, Lau M, Morrissette J, Chu N, Behrens EM. Sci Rep. 2023 Jul 29;13(1):12298. doi: 10.1038/s41598-023-39601-9. PMID: 37516815
-
Leveraging artificial intelligence in the fight against infectious diseases. Wong F, de la Fuente-Nunez C, Collins JJ. Science. 2023 Jul 14;381(6654):164-170. doi: 10.1126/science.adh1114. Epub 2023 Jul 13. PMID: 37440620
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A Registry Study of 240 Patients with X-Linked Agammaglobulinemia Living in the USA. Hernandez-Trujillo V, Zhou C, Scalchunes C, Ochs HD, Sullivan KE, Cunningham-Rundles C, Fuleihan RL, Bonilla FA, Petrovic A, Rawlings DJ, de la Morena MT. J Clin Immunol. 2023 Aug;43(6):1468-1477. doi: 10.1007/s10875-023-01502-x. Epub 2023 May 23. PMID: 37219739
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Prediction of lymphoma response to CAR T cells by deep learning-based image analysis. Tong Y, Udupa JK, Chong E, Winchell N, Sun C, Zou Y, Schuster SJ, Torigian DA. PLoS One. 2023 Jul 21;18(7):e0282573. doi: 10.1371/journal.pone.0282573. eCollection 2023. PMID: 37478073
-
TRIM11 protects against tauopathies and is down-regulated in Alzheimer's disease. Zhang ZY, Harischandra DS, Wang R, Ghaisas S, Zhao JY, McMonagle TP, Zhu G, Lacuarta KD, Song J, Trojanowski JQ, Xu H, Lee VM, Yang X. Science. 2023 Jul 28;381(6656):eadd6696. doi: 10.1126/science.add6696. Epub 2023 Jul 28. PMID: 37499037