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    Erin Zwak/Brodsky Lab & Penn Vet Imaging Core - Murine macrophages infected with Yersinia pseudo tuberculosis. Blue indicates the cell, red is a mitochondrial stain, green is a stain for Yersinia secreted effector proteins.

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    Claudio Giraudo - Polarization of lytic granules to the immunological synapse during the cytolytic process of human CD8 lymphocytes against cancer cells.

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    Gretchen Harms, Hunter lab - Stylized images of CD8+ T cells looking at differential localization of the transcription factor T-bet in mouse cells after infection with the parasite Toxoplasma gondii, using the Amnis ImageStream. In the cell in the first and third box, T-bet (red) does not co-localize with DAPI (blue), indicating that it is cytoplasmic, whereas in the cell in the second and fourth box, T-bet does co-localize with DAPI, indicating that it is nuclear. David Christian assisted in obtaining these images.

Resources

Mouse Strain Collection DataClick here for a list of current mouse strains available on campus

Immunotherapy in the Department of Pathology and Laboratory Medicine

http://pathology.med.upenn.edu/topic/immunotherapy
http://pathology.med.upenn.edu/research

I3-IBD Immunology Initiative

I3 is a translational clinical and tissue database study that is actively enrolling all Crohn’s disease and Ulcerative Colitis patients seen within the University of Pennsylvania Health System. The aim is to understand abnormalities in the immune system and other factors that impact IBD.
Investigators: Meenakshi Bewtra, M.D.
Coordinator Contact: Tram Hoang <Tram.Hoang@uphs.upenn.edu>

School of Medicine

Laboratory/Molecular Cores:

Other Laboratory/Molecular Services:

Clinical Health Service Research Core:

Center for Molecular Studies in Digestive and Liver Diseases:

SOM Screening Core

School of Arts and Sciences

School of Dental Medicine

School of Veterinary Medicine:

Other

Journal Publications:

Professional Organizations:

Other: